New Study Suggests Pathway. The gut microbiome – millions of bacteria and other microbes that live in the intestines – is known to be altered in people with MS. A team from Rutgers University may have found how damaging immune activity in MS triggers these changes in gut bacteria.
Multiple sclerosis is a chronic immune-mediated disease of the brain and spinal cord resulting in physical and cognitive impairment in young adults. It is hypothesized that a disrupted bacterial and viral gut microbiota is a part of the pathogenesis mediating disease impact through an altered gut microbiota-brain axis.
The gut microbiome altered in MS. Probiotics can naturally provoke the anti-inflammatory peripheral immune response in MS patients. Modulating the gut microbiome using probiotics is beneficial to MStreatment.
High doses of other vitamins can antagonize your immune-modulating, immunosuppressive therapies used to manage MS. Supplements that stimulate the immune system should be avoided in high doses. Those include selenium, zinc, B1, B2, folic acid, B6, vitamin A, biotin, magnesium, copper, and manganese.
While constipation is the most common pattern of bowel dysfunction in people with MS, the opposite can also be true and bowel function can actually “speed up”, causing loose stools, diarrhea, and incontinence. Sometimes, loose stools are caused by foods in your diet.
The 'MS hug' is symptom of MS that feels like an uncomfortable, sometimes painful feeling of tightness or pressure, usually around your stomach or chest. The pain or tightness can stretch all around the chest or stomach, or it can be just on one side.
Multiple sclerosis (MS) is an autoimmune disease of the central nervous system that can affect the brain, spinal cord and optic nerves.
The case for Epstein-Barr virus (EBV)
The studies found that: Antibodies (immune proteins that indicate a person has been exposed) to EBV were significantly higher in people who eventually developed MS than in control samples of people who did not get the disease.
EBV. Among gammaherpesviruses, EBV has been the most extensively studied as a potential agent in the pathogenesis of MS. EBV is ubiquitous, with seropositivity rates ranging from 85 to 95%.
Surveys for patient pain indicate that the most common pain syndromes experienced in MS are: continuous burning in extremities; headache; back pain; and painful tonic spasms.
The human gastrointestinal tract is home to a diverse community of microbes known as the gut microbiome. “Recent research has suggested that the gut microbiota may be involved in the development of neurological diseases, including MS,” Dr.
MS can damage the nerves that affect your muscles. This can cause acute or paroxysmal pain in the form of spasms. Your arms and legs might shoot out uncontrollably and might have pain like cramping or pulling. Nerve pain can also be chronic in the form of painful or unusual sensations on your skin.
His team found that about two-thirds of MS patients experience at least one chronic gastrointestinal symptom, and that 20% of MS patients experience symptoms compatible with irritable bowel syndrome (IBS). This rate of IBS symptoms is a little more than twice the rate seen in the general population.
The most common comorbidities that occur alongside MS include depression, anxiety disorders, high blood pressure, high cholesterol, and lung disease — however, some people living with MS may also experience inflammatory bowel disease (IBD).
MS may affect swallowing in a number of ways by causing difficulty managing solids or liquids, frequent throat clearing during eating or drinking, a feeling that food is stuck in the throat, or coughing or a choking sensation when eating or drinking.
Magnesium is often prescribed for nocturnal leg cramps or general muscle cramps, and some healthcare providers suggest it can be used to ease the muscle spasms of MS.
One study noted young people with MS who took a calcium, vitamin D, and magnesium supplement had a reduced number of relapses. The study authors theorized that magnesium could play a role in the growth and stability of myelin.
It isn't completely clear how supplements may affect MS, but they are thought to have an anti-inflammatory effect, a restorative effect on myelin, or both. The three with the most scientific support for this use are biotin, vitamin D, and omega-3 fatty acids.
Lesions in the brain may affect cognitive abilities. Some people with MS have trouble with memory, attention and concentration, multitasking and decision-making, says Dr. Scherz. The changes are usually mild at the beginning, but can be frustrating as time goes by.