While he lives in the Upside Down, Vecna can psychically reach into the human world, kind of like the Mind Flayer's connection with Will. He makes his presence known in Hawkins by murdering the town's teenagers in a truly gruesome fashion, all through mental connections (which is especially terrifying).
While intending to get his revenge on Eleven and Brenner, Vecna also goes after victims who have dealt with traumatizing experiences in the past (reminiscent of his childhood and his time at the Hawkins lab).
According to Henry Creel, he was brought to Dr. Brenner when his mother caught on to his mysterious psychic powers.
Essentially, Vecna hates humanity, and wants to take over their world. He had hoped that Eleven would help him achieve this goal. But when he realised she wouldn't, Vecna instead used her.
So the connection between Will and Vec — Can I call Vecna/Henry/One just “Vec”? — is one of sheer chance. They are connected because Will was the first victim. That's it.
Then Eleven—who in this future moment discovers that she in fact does not have the blood of her siblings on her hands—defeats Henry Creel, sending him to the Upside Down where he gets blasted by lightening and burnt to a crisp and, thus, becomes Vecna.
His method of killing is ritualized. Vecna started twisting bodies and removing eyes before imprisonment in the UD to fuel its own individual power. It takes the eyes to help hold the souls in darkness and because it did not wish to be observed.
In 4th edition, the Open Grave book shows the leader of the cult of Vecna is a lich named Mauthereign.
Realizing he had tremendous psychic power, he haunted his family with visions before ultimately killing most of them. His father was framed for the murders and locked away in a mental hospital as a disturbed serial killer. Henry then found himself in the care of Brenner, who decided he wanted more kids like the boy.
As Vecna, he uses these mental abilities as a way to psychologically weaken and lure in his victims – much in a way that Pennywise, Freddie Kruger, and Pinhead do. (All of which have been cited by show creators the Duffer brothers as inspirations for the villain.) But he does have a surprising weakness: music.
When One massacres the rest of the children in Hawkins Lab, Eleven banishes him to the Upside Down in the same way she banishes the Demogorgon from season one. One is sent hurtling through the Mind Flayer's lightning and is horribly disfigured, transforming into Vecna.
In simple words, Vecna needs a total of four gates to take over Hawkins and rule it. Now, you must be thinking, why is Vecna killing people if he can take over the complete Hawkins? Well, in one of the previous episodes, it was revealed that with each person Vecna kills, he creates an opening to the real world.
He believed that the construct of time and monotony needed to be destroyed. So, in his mind, by destroying humanity, he was doing it favor. That's what makes him so evil.
She breaks free, momentarily incapacitates Vecna, and runs with the determination to live toward her friends, dodging debris that Vecna throws in her path. Max hurls herself through the portal, awakes from the trance, and is held by Lucas (Caleb McLaughlin). "I thought we lost you," he cries. "I'm still here.
This is a reference to the D&D character Vecna, for whom this Vecna is named; the D&D Vecna has a monstrous hand infused with dark magic. The design of Vecna's hand is also a nod to Freddy Krueger, the Nightmare on Elm Street villain who had a huge influence on this season in general.
Based on the flashback in “The Hellfire Club”, he killed an estimated 21 people: 13 lab subjects, two orderlies, two guards, Ten, Alec, Dr. Ellis, and Six. A flashback during “The Massacre at Hawkins Lab” later reveals that Vecna killed even more people in Hawkins Lab than we thought.
Mike, on the other side tries to give strength to Eleven, who is at risk as she is captured by Vecna. Eleven gathers her strength and overpowers Vecna, who's just about to kill Max.
Eleven has a memory during this episode and realizes that 001/Henry Creel (Jamie Campbell Bower) wants her to join him on his evil journey, and she banished him to the Upside Down. 001 then transformed into Vecna, the horrifying Stranger Things villain.
Vecna isn't as terrifying in the bathroom. Actor Jamie Campbell Bower, who played the complicated villain in “Stranger Things 4,” revealed that his terrifying Freddy Krueger-esque full-body prosthetics included a “flap” for him to use the restroom without getting out of costume.
Vecna feeds off his victims' trauma and haunts them with their own darkest thoughts.
Though they're clouded with cataracts, Vecna in Stranger Things has both of his eyes.
"Vecna seems to be actually intrigued by Nancy being able to figure him out, to be able to get this close to the truth... I think this is more Vecna's narcissistic traits that pull him to Nancy, why he wants to give her this information."
Following Eleven's resistance, Vecna sought after Eleven's 'power', which he identified as "a means to open [his] own doors" (gates).
More like this. After previously having tricked Eleven into destroying the chip, Peter goes on a killing spree in the lab until a confrontation with Eleven ended in her casting him into the Upside Down - where after falling through various dimensions and sustaining various injuries, Peter was transformed into Vecna.