The usual dose is 40mg – two 20mg tablets, taken once a day. If you have kidney or liver problems your doctor might decrease the starting dose to 10mg or 20mg.
by Drugs.com
The maximum recommended dose of Cialis is 20mg daily. Increasing the dose to 40mg might just increase the intensity of side effects and may not actually deal with the erectile dysfunction problem.
Never take 2 doses at the same time. Never take an extra dose to make up for a forgotten one.
Tadalafil 20 mg how long does it last? While other PDE5 inhibitors usually need to be taken within a specific window prior to anticipated sexual activity, Tadalafil is effective for a longer period of time. The effects of Tadalafil can be seen for 24 to 36 hours. In some cases, Tadalafil can last up to 72 hours.
Do not take more than 1 tablet a day. Your doctor may increase or decrease your dose, depending on how well it works and how often you take it. The effects may last longer than 24 hours, so you're not recommended to take the 10mg or 20mg tablets every day.
Tadalafil, the active ingredient in the medication Cialis®, is one of the most effective and widely used options on the market for treating erectile dysfunction, or ED.
Maximum effect: 2 hours
After 2 hours, the maximum concentration of the drug is in the bloodstream.
The 'as required' Tadalafil (generic Cialis) has an advantage over Sildenafil in that it lasts a lot longer – up to 36 hours (compared with 4-5 hours for Sildenafil).
CrCl 30 to 50 mL/min: 5 mg orally once a day. The maximum dose is 10 mg not more than once in every 48 hours. CrCl less than 30 mL/min or on hemodialysis: The maximum dose is 5 mg orally once every 72 hours.
Using them incorrectly — having the wrong dosage or not following instructions — can cause Cialis not to work. Cialis might also fail if your ED is related to psychological issues — performance anxiety, intimacy issues, low self-confidence and depression can all affect your erections.
The approved dosages of Cialis for ED, BPH symptoms, or both, are between 2.5 mg and 20 mg a day or as needed. Dosages higher than 20 mg a day haven't been studied, and it's not known what side effects may occur with them. For example, if you take your “as-needed” dose of 20 mg twice a day, you'll end up taking 40 mg.
Unlike Viagra, for instance, which can work for a few hours after the medication is taken, Tadalafil can be effective for up to 36 hours from just a single dose, according to the National Library of Medicine.
Fifty-two percent of men taking tadalafil 20 mg had at least one successful intercourse attempt within 30 minutes compared to 35.1% of men taking placebo (P = 0.038). Conclusions: This stopwatch-based study demonstrated a pharmacodynamic effect within 30 minutes after dosing for tadalafil 10 and 20 mg.
Response and effectiveness. Peak plasma concentrations of Cialis are reached within 30 minutes to six hours (average time two hours) of a dose. Effects of 'as needed' Cialis last for up to 36 hours.
You should avoid or limit the use of alcohol while being treated with tadalafil, and use caution when getting up from a sitting or lying position. You may also want to avoid drinking large amounts of grapefruit juice, since it may increase the blood levels and effects of tadalafil.
Researchers analyzed the health records of more than 70,000 men with erectile dysfunction and found that those who were prescribed Viagra (sildenafil), Cialis (tadalafil), Levitra (vardenafil), or similar drugs called phosphodiesterase type 5 (PDE-5) inhibitors also had: 39 percent lower death rate due to heart disease.
So to answer the above question, no, Viagra would not necessarily give a stronger erection than Cialis, and vice versa. However, Cialis will last longer and can help achieve one or more erections for up to 36 hours. This is considerably longer than Viagra, which is typically effective for 4-6 hours.
A daily dose of 5mg tadalafil can be safely used in the treatment of erectile dysfunction and LUTS, that prolongs the ejaculatory latency time.
By controlling the enzyme, tadalafil helps to maintain an erection after the penis is stroked by increasing blood flow to the penis. Without physical action to the penis, such as that occurring during sexual intercourse, tadalafil will not work to cause an erection.
Tadalafil shares a similar efficacy and safety with sildenafil and significantly improves patients' sexual confidence. Furthermore, patients and their partners prefer tadalafil to sildenafil. Hence, tadalafil may be a better choice for ED treatment.
Poor control of high blood pressure, high cholesterol, poor control of diabetes, and weight gain are some of the common causes of why tadalafil (Cialis) may stop working well. Addressing underlying problems is important not only for sexual health but also for heart health.
When taken on demand, tadalafil 20 mg versus placebo allows a range of 62%–74% (vs 0%–33%) of successful intercourse attempt rate up to 36 h (p<0.001 up to 24 h; p=0.017 up to 36 h) (Allen et al 2004; Seftel et al 2005).
Do not break or split a Cialis tablet. Swallow it whole. Take the medicine at the same time each day, with or without food.