Taking melatonin at a dose of 20 mg is not recommended. It can lead to a melatonin overdose. This can cause daytime sleepiness, headaches, and dizziness. To avoid an overdose on melatonin, you should not take more than 10 mg.
Too much melatonin can lead to unwanted side effects. But it's very rare that an overdose of the supplement could kill you. Each form of medication has a lethal dose, or LD 50.
Doses of 10 milligrams or higher can cause side effects like drowsiness and headache. Other symptoms of melatonin overdose. View Source include changes in blood pressure, dizziness, headaches, nausea, and vivid dreams or nightmares.
Melatonin is generally safe for most people, and many people won't experience major complications when taking too much. Even so, an overdose can cause unpleasant side effects. Keep your dose to no more than 1 to 3 mg per night.
According to the foundation, there is no official recommended melatonin dose for adults or children, but the “safe and effective” range is between 0.5 to 5 milligrams. To date, there is no definite amount that constitutes a melatonin overdose, according to Poison Control.
If you plan on using melatonin to help you sleep, it's best to take it two or three hours before your bedtime. On the flip side, if you find yourself unable to sleep in the middle of the night, keep in mind that popping a melatonin at midnight won't necessarily have immediate results.
Generally, an adult dose is thought to be between 1 and 10 mg. Doses near the 30 mg mark are usually considered to be harmful.
The usual starting dose is one 2mg slow release tablet taken 30 minutes to 1 hour before bedtime. Sometimes the dose may gradually be increased to 2 to 3 tablets before bedtime, depending on how well it works and whether you have any side effects. The maximum dose is 5 tablets (10mg) once daily.
Is it possible to overdose on melatonin? In short: no. There's no good evidence that taking too much melatonin can lead to a life-threatening overdose the way other sedating drugs can.
There has never been a case reported of anyone dying from too much melatonin, or even becoming seriously ill, so no, you cannot really overdose in the fatal sense. On the other hand, you can certainly take too much melatonin, which can produce adverse side-effects you likely want to avoid.
There is no official recommended maximum dose of melatonin for adults, but a range of 0.5 mg to 5 mg appears to be safe and effective. Generally speaking, most people produce enough melatonin to sleep well, but if you need a little extra to add to their sleep cycle, you probably don't need more than 3 mg.
Most people overdo it with melatonin by taking upward of 10 milligrams or more prior to bed and then claim it doesn't work. Taking too much melatonin can actually cause rebound insomnia —either rendering the supplement ineffective or worse, exacerbating your already sleepless nights further.
Melatonin lasts for about four hours before it's 95 percent absorbed by your body, meaning you'll want to take your melatonin supplement 30 minutes to two hours before you plan to sleep for the best results.
Regardless of whether it truly helps with sleep or not, Dr. Ramkissoon doesn't recommend taking melatonin long-term.
If someone takes too much melatonin, he or she might experience sleepiness, headache, nausea, and perhaps even agitation. There is no antidote for melatonin overdose, and significant toxicity is not expected to occur even after consumption of relatively large doses of it.
The range of the maximum prescribed melatonin dose per kg of body weight was 0.01–0.85 mg/kg for first prescriptions and 0.02–1.53 mg/kg for iterated prescriptions.
Melatonin can be used to treat delayed sleep phase and circadian rhythm sleep disorders in the blind and provide some insomnia relief. Treat melatonin as you would any sleeping pill and use it under your doctor's supervision.
Possible symptoms of too much melatonin include: Headache. Hypotension (low blood pressure) Hypertension (high blood pressure)
In addition to vivid dreams or nightmares, some adults and children report dizziness, headaches, and even agitation as the most common side effects of short-term melatonin use. Long-term side effects are not well documented.
OTC melatonin can stay in the body for 4–10 hours, depending on the dose and formulation. People should avoid taking melatonin at or after their intended bedtime. Doing so can shift their sleep-wake cycle and lead to daytime sleepiness.
The best time to take melatonin is when you can sleep for at least six hours. With less than six hours of sleep, the additional melatonin may leave you groggier than usual and tired the next day. Therefore, you do not want to take melatonin in the morning or when you won't be able to sleep long enough.
Sleep medications are considered a last resort for those with adult ADHD and generally aren't recommended. That's especially true if you're taking a stimulant ADHD medication. Adding a sleep-inducing drug at night sets up a “vicious cycle” of stimulation and sedation, Dr. Kushida says.