Is ankylosing spondylitis a form of MS?

While both multiple sclerosis and ankylosing spondylitis are autoimmune diseases, they are otherwise unrelated and rarely coexist. MS is a disease of the brain and spinal cord, whereas ankylosing spondylitis is a type of inflammatory arthritis that mainly affects the spinal and sacroiliac joints.

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Can ankylosing spondylitis turn into MS?

Background: Although ankylosing spondylitis (AS) is primarily a disease of the spine and the large joints, it may also have extra-articular involvement. There are limited cases of AS patients developing multiple sclerosis (MS).

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Can you have both MS and ankylosing spondylitis?

Background: Multiple sclerosis (MS) only rarely coexists with ankylosing spondylitis (AS). The optimal management of these patients represents a major challenge. Methods: In the present study, we report 2 cases of AS with definite MS comorbidity.

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What diseases are associated with ankylosing spondylitis?

Complications Ankylosing spondylitis
  • Reduced flexibility. ...
  • Joint damage. ...
  • Iritis. ...
  • Osteoporosis and spinal fractures. ...
  • Cardiovascular disease. ...
  • Cauda equina syndrome. ...
  • Psoriasis. ...
  • Inflammatory bowel disease (IBD)

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Can ankylosing spondylitis cause brain lesions?

Inflammatory diseases like ankylosing spondylitis can result in damage to brain tissue. When this occurs, brain lesions can form. These abnormalities can be diagnosed through medical imaging (such as an MRI or CT scan).

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Ankylosing Spondylitis | HLA-B27, Pathophysiology, Signs & Symptoms, Diagnosis, Treatment

31 related questions found

Is ankylosing spondylitis a neurological disorder?

Ankylosing spondylitis is a chronic inflammatory disease that often causes pain in your back, hips, and other joints. It can also affect your brain and your ability to perform normal functions. These changes can cause brain fog, memory loss, or brain lesions.

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What is the root cause of ankylosing spondylitis?

Ankylosing spondylitis has no known specific cause, though genetic factors seem to be involved. In particular, people who have a gene called HLA-B27 are at a greatly increased risk of developing ankylosing spondylitis. However, only some people with the gene develop the condition.

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What autoimmune disease goes with ankylosing spondylitis?

"B27 disease" is a new autoimmune disease that afflicts millions of people throughout the world. "B27 disease" occurs in individuals who have ankylosing spondylitis (AS) or preankylosing spondylitis and/or uveitis and are also positive for HLA-B27.

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Will I end up in a wheelchair with ankylosing spondylitis?

It is a rare disease, there is no cure, and you will end up in a wheelchair.

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Is spondylosis a symptom of MS?

Conclusions: Patients with MS present more frequently spondylosis which is associated with younger age, more severe disability and extensive lesions in the brain.

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What autoimmune diseases are related to MS?

You have a slightly higher risk of developing MS if you have other autoimmune disorders such as thyroid disease, pernicious anemia, psoriasis, type 1 diabetes or inflammatory bowel disease.

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What diseases mimic multiple sclerosis?

These include fibromyalgia and vitamin B12 deficiency, muscular dystrophy (MD), amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease), migraine, hypo-thyroidism, hypertension, Beçhets, Arnold-Chiari deformity, and mitochondrial disorders, although your neurologist can usually rule them out quite easily.

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Who is prone to ankylosing spondylitis?

Most people develop symptoms of ankylosing spondylitis before age 45. However, some people develop the disease when they are children or teens. Other conditions. People who have Crohn's disease, ulcerative colitis, or psoriasis may be more likely to develop the disease.

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How bad does ankylosing spondylitis get?

Some people with AS are able to remain fully independent or minimally disabled in the long term. However, some people eventually become severely disabled as a result of the bones in their spine fusing in a fixed position and damage to other joints, such as the hips or knees.

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What aggravates ankylosing spondylitis?

Some foods can trigger ankylosing spondylitis, so it's important to avoid certain foods to prevent inflammation. These include foods that are high in fat, salt, and sugar; processed foods, dairy products, alcohol, caffeine, artificial sweeteners, and others.

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Are you born with ankylosing spondylitis?

Can ankylosing spondylitis be inherited? AS can run in families, and the HLA-B27 gene variant can be inherited from another family member. If you have AS and tests show you carry the HLA-B27 gene variant then there is a 1 in 2 chance that you could pass on the gene variant to any children you have.

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What are the 4 body areas affected by ankylosing spondylitis?

Ankylosing spondylitis may affect more than the spine. The disease may inflame joints in the pelvis, shoulders, hips and knees, and between the spine and ribs.

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What is the life expectancy of someone with ankylosing spondylitis?

Life expectancy for people with ankylosing spondylitis is the same as that of the general population, except for patients with severe symptoms and complications. Ankylosing spondylitis is a chronic, inflammatory autoimmune disease.

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What is the hallmark of ankylosing spondylitis?

Purpose of review: The hallmark of ankylosing spondylitis is acute and chronic spinal inflammation initiating in the sacroiliac joints, often coupled with enthesitis, presenting as chronic inflammation at the sites of ligamentous and tendinous insertions into bone.

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What is the gold standard for ankylosing spondylitis?

Evaluation of SIJ on pelvic X-rays according to the modified New York (mNY) criteria served for decades as the gold standard to ascertain a diagnosis of ankylosing spondylitis (AS) at a given time point.

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What is the most important test for ankylosing spondylitis?

Magnetic resonance imaging (MRI) uses energy from a powerful magnet to produce signals that create a series of cross-sectional images. These images or “slices” are analyzed by a computer to produce an image of the joint. MRI can help diagnose ankylosing spondylitis in the early stages of the disease.

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Why does ankylosing spondylitis affect the eyes?

Ankylosing spondylitis can cause inflammation throughout the body, including the eyes. This can lead to a condition called uveitis, which often causes blurred vision. What are the early signs of ankylosing spondylitis?

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What is another name for ankylosing spondylitis?

What Is Ankylosing Spondylitis? Ankylosing spondylitis (AS) is a rare type of arthritis that causes pain and stiffness in your spine. This lifelong condition, also known as Bechterew disease, usually starts in your lower back.

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What is MS most commonly misdiagnosed as?

Some conditions that doctors may commonly misdiagnose as MS include migraine, RIS, spondylopathy, and neuropathy. To accurately diagnose MS, doctors must rule out conditions with similar symptoms and look for signs and symptoms specific to MS. As such, the process of diagnosing MS may be lengthy and complex.

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