Bipolar disorder is frequently inherited, with genetic factors accounting for approximately 80% of the cause of the condition. Bipolar disorder is the most likely psychiatric disorder to be passed down from family. If one parent has bipolar disorder, there's a 10% chance that their child will develop the illness.
Childhood traumatic events are risk factors for developing bipolar disorders, in addition to a more severe clinical presentation over time (primarily an earlier age at onset and an increased risk of suicide attempt and substance misuse).
The exact cause of bipolar disorder is unknown. Experts believe there are a number of factors that work together to make a person more likely to develop it. These are thought to be a complex mix of physical, environmental and social factors.
If you live with a mood disorder (depression or bipolar disorder), a traumatic event can disrupt your routine and impact your therapy. It may even trigger an episode of mania or a deepening of depression.
Cyclothymia symptoms alternate between emotional highs and lows. The highs of cyclothymia include symptoms of an elevated mood (hypomanic symptoms). The lows consist of mild or moderate depressive symptoms. Cyclothymia symptoms are similar to those of bipolar I or II disorder, but they're less severe.
Defects in mitochondrial DNA sequences may contribute to a predisposition to such complex diseases as diabetes and bipolar disorder. Therefore, if all bipolar disorder patients have mitochondrial predisposition genes, then the transition of bipolar disorder from the mother's side would be higher.
People with bipolar experience both episodes of severe depression and episodes of mania – overwhelming joy, excitement or happiness, huge energy, a reduced need for sleep, and reduced inhibitions. The experience of bipolar is uniquely personal. No two people have exactly the same experience.
Although bipolar disorder can occur at any age, typically it's diagnosed in the teenage years or early 20s.
Substance Abuse
People who abuse drugs or alcohol are also at risk for developing bipolar disorder. Substance use doesn't cause the disorder, but it can make mood episodes worse or hasten the onset of symptoms.
Persons with bipolar disorder are at significantly increased risk for violence, with some history of violent behavior ranging from 9.4% to just under 50%, often in the presence of comorbid diagnoses. Bipolar patients are prone to agitation that can result in impulsive aggression during manic and mixed episodes.
They found that 12 risk genes for bipolar disorder were also linked to intelligence. In 75 % of these genes, bipolar disorder risk was associated with higher intelligence. In schizophrenia, there was also a genetic overlap with intelligence, but a higher proportion of the genes was associated with cognitive impairment.
Mania in particular tends to trigger aggressive emotions and anger. The racing thoughts and high energy levels you experience can leave you feeling angry, irritable, and frustrated. Those angry emotions, in turn, can cause aggressive and inappropriate behaviors.
Without proper treatment, people with hypomania may develop severe mania or depression. "Bipolar disorder may also be present in a mixed state, in which you might experience both mania and depression at the same time.
Bipolar disorder can cause your mood to swing from an extreme high to an extreme low. Manic symptoms can include increased energy, excitement, impulsive behaviour, and agitation. Depressive symptoms can include lack of energy, feeling worthless, low self-esteem and suicidal thoughts.
Drugs with a definite propensity to cause manic symptoms include levodopa, corticosteroids and anabolic-androgenic steroids. Antidepressants of the tricyclic and monoamine oxidase inhibitor classes can induce mania in patients with pre-existing bipolar affective disorder.
The risk of developing dementia is much higher among people who've had bipolar disorder, according to several studies. A 2020 analysis determined that people with bipolar disorder are about three times more likely to develop dementia, while another expansive analysis also found a significantly increased risk.
The Genomind Pharmacogenetic (PGx) test looks at 24 genes related to mental health treatment and can be used to help determine medication options to manage bipolar disorder.
As mentioned previously, the most common misdiagnosis for bipolar patients is unipolar depression. An incorrect diagnosis of unipolar depression carries the risk of inappropriate treatment with antidepressants, which can result in manic episodes and trigger rapid cycling.
The main sign of bipolar disorder is extreme mood swings that go from emotional highs to emotional lows. Manic episodes cause people to seem very energetic, euphoric, or irritable. During depressive episodes, your loved one may seem sad, upset, or tired all the time.
MRIs and CT scans can provide detailed images of the brain and its structures. But currently, doctors don't use them to diagnose bipolar disorder. Detecting bipolar disorder is typically done through a diagnostic interview with a mental health professional.
Thousands of Americans who are diagnosed with this condition every year are unable to work and hold employment due to their symptoms. If an individual is unable to work because of bipolar disorder, he or she may qualify for either Supplement Security Income (SSI) or Social Security Disability Insurance (SSDI).