CoQ10 supplements aren't necessary for everyone. “If you have a balanced diet, and if you're young and healthy, you probably have enough CoQ10 in your body,” Peart says.
The Bottom Line
Typically, 90–200 mg of CoQ10 per day are recommended, though some conditions may require higher dosages of 300–600 mg. CoQ10 is a relatively well-tolerated and safe supplement that may benefit a wide variety of people looking for a natural way to boost health.
If left untreated, low blood pressure can become life-threatening. If you're taking a blood thinner, such as warfarin or aspirin, do not use CoQ10 without consulting your healthcare provider. “CoQ10 can reduce the efficacy of a blood thinner,” explains Splaver.
CoQ10 supplements may improve heart health and blood sugar and help manage high blood pressure in people with diabetes. Preliminary studies found that CoQ10 improves blood sugar control. But other studies show no effect. If you have diabetes, talk to your doctor or registered dietitian before taking CoQ10.
CoQ10 is safe for most people after the age of 18 and is encouraged for anyone with mitochondrial dysfunction, over the age of 35, or anyone trying or planning to conceive.
CoQ10 positively influences the age-affected cellular metabolism and enables to combat signs of aging starting at the cellular level. As a consequence topical application of CoQ10 is beneficial for human skin as it rapidly improves mitochondrial function in skin in vivo.
If you eat sources of saturated fat, like beef, switching to foods with omega-3 fatty acids, like fatty fish, can help lower your heart disease risk. CoQ10 may offer benefits if you already struggle with cardiovascular disease risk or you've had a heart attack.
In some cases, doses may be gradually increased to 3000 mg per day. For heart failure and fluid build up in the body (congestive heart failure or CHF): 30 mg once daily, or up to 300 mg per day divided into two or three doses for up to 2 years. Also, 2 mg/kg daily for up to one year has been used.
CoQ10 supplementation is associated with increased energy levels. As with other supplements that boost energy levels, CoQ10 users have reported side effects such as slight stomach upset, headaches, feeling jittery or “wired,” and experiencing mild insomnia.
If you have been taking CoQ10 supplements while trying to conceive or through fertility treatments, we recommend stopping as soon as you are pregnant UNTIL you discuss it with your doctor.
In addition to reducing the risk of cardiovascular problems in patients with liver disease, CoQ10 supplementation may also benefit the disease process within the liver by reducing inflammation and oxidative stress.
For our patients, daily supplementation of CoQ10 can lead to doubling their weight loss over several months with the same calorie intake. Also, CoQ10 improves stamina and motivation to exercise, which further helps to achieve an optimal weight.
Many cardiologists place their patients on CoQ10 to help cardiac function as well as to reduce the bad side effects of statin cholesterol drugs. The supplement also may help decrease the pain of rheumatoid arthritis by decreasing the bad inflammatory chemicals that lead to cartilage breakdown.
Answer: Yes, it is possible that CoQ10 is making it harder for you to fall asleep. Fortunately, there are ways to minimize this effect. Learn more in the Concerns and Cautions section of the CoQ10 and Ubiquinol Supplements Review.
As has already been mentioned, CoQ10 is sometimes associated with fatigue.
No interactions were found between CoQ10 and Vitamin D3.
The findings showed that taking CoQ10 by patients with CAD significantly decreased total-cholesterol (SMD -1.07; 95% CI, − 1.94, − 0.21, P = 0.01) and increased HDL-cholesterol levels (SMD 1.30; 95% CI, 0.20, 2.41, P = 0.02).
CoQ10 stimulates the cell's powerhouse, an organelle called the mitochondria, to produce more energy in the form of Adenosine Triphosphate (ATP). More specifically, it speeds up the process called the electron transport chain which produces 95% of the cell's ATP.
Recent research links low blood levels of CoQ10 with low levels of heart-protective “good” cholesterol which in turn may further increase risk for heart disease. Cholesterol-lowering statins may also reduce blood levels of CoQ10.
Ubiquinol has 2x greater bioavailability and increases levels about 4x, where CoQ10 only increases 2x. This means you can take ½ the dose when you use Ubiquinol. If we want 100mg of CoQ10, you can use 50mg of Ubiquinol.
No interactions were found between CoQ10 and Omega 3-6-9 Complex. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
A human study shows that CoQ10 reduces wrinkles by nearly 25% and promotes smoother skin by up to 82%. Laboratory analysis reveals how CoQ10 restores mitochondrial function in aged skin. Scientifically reviewed by: Dr. Vanessa Pavey, ND, in May 2022.
There are many benefits CoQ10 can potentially provide for younger looking skin. For example, replenishing skin cells, improving skin tone, reducing the appearance of fine lines and wrinkles and working as an antioxidant. CoQ10 can be found in various skincare products and is an ingredient that mixes well with others.
- Q10 helps to reduce the emergence of fine lines & wrinkles
With all the energy coenzyme Q10 provides the skin and with it helping to support the production of collagen, it is a highly effective ingredient in creams that help to fight the signs of ageing skin - such as fine lines and wrinkles.