There is nothing in canon that signifies Doflamingo missing an eye. This is just one of the many unproven theories, something a series as vast as One Piece would be cursed with. Unless Oda clarifies, the answer stays no.
The character is seen with a couple different pairs of shades but never without them, and One Piece creator Eiichiro Oda finally gave fans an inside look at what the pirate had underneath his glasses.
It could be he has some messed up eyes like Jango did, or it could be Oda just really likes drawing his glasses. Then I thought to myself, what if Doflamingo is blind? I mean the guy has been wearing these glasses since he was a child. Of course there are a few holes and even less evidence for this.
He generally dresses in flamboyant clothes. In reference to his animal theme, the flamingo, his clothes are brightly colored, with his light pink feather coat most distinctly of all. Doflamingo sports a pair of curved, thin white sunglasses, which appear to serve as his eyesight with red or purple lenses.
Flamingo chicks have gray eyes for approximately the first year of life. Adult flamingos have yellow eyes.
- We saw people shooting many arrows and one guy shot an arrow right into the direction of Doffy's left eye and we hear the sound of an arrow landing in the moment Doffy wakes up bathed in sweat. In that time we saw him opening only his right eye. - The left eye on his jolly roger is struck through.
His real name is Don Quixote Doflamingo AKA The Heavenly Demon, or "Joker" in the underworld. He produces artificial Devil Fruits called "SMILEs." He wields the power of the String-String Fruit and strings he uses can manipulate humans, slice through any object, and even loop around clouds to lift him.
According to Oda, Doflamingo and Viola shared a "romantic" relationship. Having said so, due to Viola's identity, it's highly unlikely that it was a consensual one. This is one of the cases in which One Piece showcased its underlying darkness.
In the anime, some Haki users are shown surrounded by different color auras (such as red for Luffy, purple for Doflamingo or pink for Big Mom) even if they are not using Haki at that moment.
In the Post-War arc, one of the Five Elders stated that "D." means danger. After the timeskip, Law mentioned the Will of D. once more when Doflamingo asked him why he had so much faith in Luffy. After visiting Laugh Tale, Kozuki Oden mentioned that he and the Roger Pirates had learned the meaning of the D. name.
And finally, Doflamingo is so beloved because he never really adheres to the politickin' of the Grand Line. During the Marineford War, he dismisses the ideas that either pirates or Marines are fighting for righteousness or true "justice." According to him, whoever wins becomes Justice.
Doflamingo's short temper has often been one of his most glaring weaknesses. Whenever he is dealt moderate injuries - or if his plans are disrupted - his forehead bulges noticeably. Mentions of or thoughts about his past are a particularly effective way to arouse his anger.
Because he's just a big guy. There is no rhyme or reason for it. One Piece is a surreal series where he have humans with goofy features impossible in real life, and in plenty of cases they are also much larger than any human can be in real life.
7 Doflamingo Is 41 Years Old
Despite his spry gait, blond hair, and cocky attitude, Doflamingo is much older than he appears. At 41, he has dominated Dressrosa and been active on a global stage for several decades by the time of his defeat.
At age 17, Doflamingo was present at the execution of the Pirate King, Gol D. Roger. At age 24, he was reunited with his brother, Rosinante, who replaced Vergo as Corazon on Doflamingo's crew. Despite being brothers, Rosinante was secretly undercover as a marine, plotting to take down Doflamingo and his crew.
During the Dressrosa saga, the Heavenly Yaksha (nickname of Donquixote Doflamingo) was almost taken out by Law's Gamma Knife technique. However, his powerful Ito Ito no Mi allowed him to stitch his organs back together. Law didn't have the physical strength or stamina to win this particular battle.
50 at the ln-game shop. White Haki spirit color is the rarest color and cannot be obtained with robux.
The Armament haki (busoshoku) is the ability to project your spirit into armor. An example of how it represents one's spirit is Vergo's purple haki as per debut. Vergo maybe mastered his armament haki. So this purple tint to his haki could've been his spirit's nature, the same to Luffy where he got his own shade.
It is one of few One Piece pairings where there has been a substantial amount of time spent together, as Mihawk and Perona have been by each other's side now for at least two years. Their moments can be seen closely as husband and wife, with how Perona tries to care for Mihawk and how he has shown worry for her safety.
Kaido is just his biggest fear because he knows Kaido won't accept delays in his SMILE deliveries. If that ever happened (ie. Caesar Clown is kidnapped), he'd basically lay waste to Doflamingo and his entire army.
Doflamingo's favorite food is lobster. His least favorite food is barbecue due to the trauma he went through as a child.
Dracule Mihawk (ジュラキュール・ミホーク, Jurakyūru Mihōku), also known as "Hawk-Eye" Mihawk (鷹の目のミホーク, Taka no Me no Mihōku) by those in the seas, is a fictional character and deuteragonist from the One Piece series.
Meanwhile, Kyros, now remembered by his friends and family, finishes what he started 10 years ago by cutting off Doflamingo's head.