Side effects are uncommon, but may occur in some cases. In clinical trials, vomiting and diarrhea were the most frequently reported adverse reactions.
Simparica may cause neurologic signs such as tremors, unsteadiness and/or seizures in dogs with or without a history of neurologic disorders. Simparica has not been evaluated in pregnant, breeding or lactating dogs. The most common adverse reactions in clinical trials were vomiting and diarrhea.
How long does Simparica protection last? Simparica is a monthly chewable that starts protecting in hours* and lasts for 35 days. That gives you a little wiggle room at the end of the month, in case you're late with the next month's dose.
Additionally, the chemicals in some flea treatments can be irritating to dogs, leading to discomfort and restlessness. Finally, some dogs may experience an allergic reaction to the ingredients in flea medicine, which can also lead to restlessness.
The police dog in question who was given Simparica Trio eventually recovered. It is important to help the animal detox, giving a twice-daily dose of 250-500 mg milk thistle for three to four weeks, plus a few drops of fish oil and a teaspoon of coconut oil daily.
Side effects with Simparica are not common. However, the following side effects are seen in less than 1 dog in 10,000: mild and short-lived vomiting and diarrhoea as well as tremor (shaking), ataxia (inability to coordinate body movements) or convulsions. These signs usually resolve without treatment.
Use with caution in dogs with a history of seizures or neurologic disorders. Prior to administration of SIMPARICA TRIO, dogs should be tested for existing heartworm infections. Infected dogs should be treated with an adulticide to remove adult heartworms.
Both products are safe for dogs when following directions and have been approved by the FDA to treat and prevent flea and tick infestations. While Simparica was trialed and not approved, Nexgard has not yet been evaluated for use in breeding, pregnant, or lactating dogs.
Side Effects & Warnings
Simparica is for use only in dogs, 6 months of age and older. Simparica may cause abnormal neurologic signs such as tremors, unsteadiness, and/or seizures.
Simparica Trio contains sarolaner, a member of the isoxazoline class, which has been associated with neurologic adverse reactions including tremors, ataxia, and seizures in dogs with or without a history of neurologic disorders.
But that being said, Simparica does kill an additional tick specie and is relatively faster in eliminating fleas and ticks. Hence, Simparica would be the bigger bet, but Nexgard is just as effective. So before you opt for any oral treatment, consult your vet first.
Bravecto Chew is also effective in killing adult fleas, so it can help reduce the risk of your dog getting flea bite dermatitis. If you're looking for a safe and effective flea and tick treatment for your dog, Bravecto Chew is the way to go.
It offers long-lasting protection and is generally safe for most dogs. If you are considering Simparica Trio as a solution for your pet, be sure to consult with your veterinarian to ensure that it is the right choice for your dog's age, weight, and health status.
Simparica for dogs is a drug from the isoxazoline class. This class has been linked to neurological signs such as tremors, unsteadiness, and seizures in dogs. However, the FDA considers drugs in the isoxazoline class to be safe and effective for dogs.
The cumulative deaths reported to April 2021 ranged from a high of 2,627 (24%) for fluralaner (Bravecto®) to 726 (2.8%) for afoxolaner (NexGard®) and 412 (12.7%) for sarolaner (Simparica®).
Simparica may cause neurologic signs such as tremors, unsteadiness and/or seizures in dogs with or without a history of neurologic disorders.
I have read that Simparica may cause side effects including muscle tremors, diarrhea, lethargy, anorexia, otitis externa, hyperactivity, neurological side effects, seizures, convulsions, anxiety and skin irritation.
Both products are safe for dogs when following directions and have been approved by the FDA to treat and prevent flea and tick infestations. However, unlike Bravecto, Simparica has yet to be approved for use in breeding, pregnant, or lactating dogs.
If you have a breeding dog, a pregnant dog, or a puppy between 6 and 8 weeks old, Heartgard Plus is the safest option. If you're hoping to find a broad-spectrum product that protects against fleas and ticks while it defends against internal parasites, Simparica Trio is the clear winner.
That same information showed 720 reported seizures for Bravecto in four years and 557 for Simparica in three years. For Credelio, six seizures were reported in the first six months after its approval. The manufacturers said the risk of side effects is rare, less than one in 10,000 doses sold.
Cedar oil is a good replacement for flea medications for dogs like Bravecto Chews for Dogs, Frontline Plus for Dogs, Revolution for Dogs, Simparica for Dogs, Advantage Multi for Dogs, and more.
Aside from feeding it to your pup, coconut oil can also benefit your dog's skin and coat when applied topically. Not only can coconut oil make your dog's coat look glossy and polished, but it can also help soothe irritated, itchy skin, Pendergrass says.
As Simparica is an oral treatment, there are no restrictions on swimming, bathing and shampooing before or after administration.