Healthy adults have a small amount of brain atrophy due to natural ageing, but in many people with untreated MS, brain atrophy occurs at a much faster rate. Current MS treatments aim to prevent new central nervous system lesions forming that lead to irreversible damage and brain atrophy.
Contents. You may have to adapt your daily life if you're diagnosed with multiple sclerosis (MS), but with the right care and support many people can lead long, active and healthy lives.
Average life span of 25 to 35 years after the diagnosis of MS is made are often stated. Some of the most common causes of death in MS patients are secondary complications resulting from immobility, chronic urinary tract infections, compromised swallowing and breathing.
Without treatment, approximately half of individuals with RRMS convert to SPMS within 10 years. However, with the introduction of long-term disease-modifying therapies (DMTs), fewer individuals advance to this latter form of the disease.
Benign multiple sclerosis (MS) describes a form of MS that a person may have for several years without experiencing any of the severe symptoms that the condition generally causes.
Only a small percentage of people with MS receive their diagnosis after age 50. In some cases, these people have late-onset MS. But for some, the diagnosis represents a delayed identification of years — or even decades — of unrecognized symptoms.
Outlook. The outlook for benign MS isn't clear. Some people who are diagnosed with it never go on to have a more serious disease progression, while others do. Remember, just because you have mild symptoms when you're first diagnosed with MS doesn't mean that they'll stay that way.
Multiple sclerosis (MS) is a potentially disabling disease of the brain and spinal cord (central nervous system). In MS , the immune system attacks the protective sheath (myelin) that covers nerve fibers and causes communication problems between your brain and the rest of your body.
Lifestyle Factors and MS Progression
We know lifestyle factors such as eating a healthy diet, maintaining a healthy gut microbiome, exercising regularly, and taking vitamin D are helpful for our overall health. Some, like exercise, can help with MS symptoms, prevent complications, and possibly be neuroprotective.
Four disease courses have been identified in multiple sclerosis: clinically isolated syndrome (CIS), relapsing-remitting MS (RRMS), primary progressive MS (PPMS) and secondary progressive MS (SPMS).
As you get older, MS becomes more of a progressive disease. You might notice your MS symptoms start to get worse just as you reach menopause.
Over time, this leads to a decrease in brain volume, known as brain atrophy. Healthy adults have a small amount of brain atrophy due to natural ageing, but in many people with untreated MS, brain atrophy occurs at a much faster rate.
Factors that may trigger MS include: Exposure to certain viruses or bacteria: Some research suggests that being exposed to certain infections (such as Epstein-Barr virus) can trigger MS later in life. Where you live: Your environment may play a role in your risk for developing MS.
In many patients, over a span of 5 to 15 years, the attacks begin more indolently, persist more chronically and remit less completely, gradually transforming into a pattern of steady deterioration rather than episodic flares. This pattern is referred to as secondary progressive MS.
MS can appear at any age but most commonly manifests between the ages of 20 and 40. It affects women two to three times as often as men. Almost one million people in the United States have MS, making it one of the most common causes of neurological disability among young adults in North America.
The early signs and symptoms of MS can be the same for women and men. One of the more obvious first signs of MS is a problem with vision, known as optic neuritis. This is often because it's a more concrete symptom as opposed to vaguer neurological symptoms like numbness and tingling.
What are the early signs of multiple sclerosis, a disease that affects your central nervous system? Symptoms like blurred vision, numbness, weakness and dizziness that persist for more than a day might be warnings that you need to see your doctor.
How long can MS go undiagnosed? MS is usually diagnosed between the ages of 20 and 50, but it can go undetected for years.
Muscle spasms and stiffness: Formally called spasticity, this symptom can range from mild feelings of muscle tightness to severe and painful spasms, according to the National MS Society, and it most commonly affects the legs.
There is no cure for multiple sclerosis. Treatment typically focuses on speeding recovery from attacks, reducing new radiographic and clinical relapses, slowing the progression of the disease, and managing MS symptoms. Some people have such mild symptoms that no treatment is necessary.
Some of the factors that have been suggested as possible causes of MS include: your genes – MS isn't directly inherited, but people who are related to someone with the condition are more likely to develop it; the chance of a sibling or child of someone with MS also developing it is estimated to be around 2 to 3 in 100.