Conclusions. In patients with T2DM and CHD, the 12-week intake of magnesium plus zinc had beneficial effects on FPG, HDL-cholesterol, CRP, insulin, total nitrite, TAC levels, and BDI and BAI score. This suggests that magnesium and zinc co-supplementation may be beneficial for patients with T2DM and CHD.
Some studies have shown that zinc improves glucose levels (glycaemic control) in people with diabetes. As a consequence of diabetes long‐term complications may develop, such as kidney, nerve and eye disease. Also, the risk of cardiovascular complications like heart attacks and strokes is raised.
Background: Magnesium (Mg) supplementation may help control glycemic response among type 2 diabetes (T2D) patients.
However, if you have type 2 diabetes, it's important to notify your healthcare provider before taking magnesium. This is because magnesium may increase the risk of hypoglycemia, or low blood sugar, as it may have an additive effect when combined with medication.
We demonstrated that zinc supplementation improved symptoms of diabetes such as polydipsia and increased serum level of high-density lipoprotein cholesterol, indicating that zinc supplementation has a potential beneficial effect on diabetic conditions.
Results. Magnesium and zinc significantly decreased fasting plasma glucose (FPG) (β − 9.44 mg/dL, 95% CI, − 18.30, − 0.57; P = 0.03) and insulin levels (β − 1.37 μIU/mL, 95% CI, − 2.57, − 0.18; P = 0.02).
Two recent meta-analyses have shown that Zinc supplementation reduces Fasting Blood Glucose, 2 h Post Prandial Blood Glucose and HbA1c in patients with diabetes, as well as reducing total cholesterol, LDL cholesterol and triglycerides in both patients with and without diabetes [15, 129].
Magnesium taurate may be the best form of the mineral for managing high blood sugar, according to Healthline.
Oral Mg supplements have been shown to improve fasting and postprandial glucose levels and insulin sensitivity in hypomagnesemic DM2 patients[57], to improve insulin sensitivity in non-diabetic subjects with insulin resistance[8], and to decrease C-reactive protein levels in hypomagnesemic patients with prediabetes[69] ...
Research shows that people who regularly consume good levels of magnesium through their diet and/or through supplementation are more likely to maintain healthy blood glucose balance. On the other hand, people who do not consume enough magnesium are more likely to develop problems with their blood glucose control.
High magnesium intake has been shown to improve glucose metabolism in diabetic patients and stabilize insulin levels (22).
You can also reduce the burden of prescription medications like metformin by combining it with magnesium.
Oral Magnesium Supplementation Improves Insulin Sensitivity and Metabolic Control in Type 2 Diabetic Subjects: A randomized double-blind controlled trial.
Taking a Zinc Supplement
The daily recommended dose of zinc is 12 mg for women and 15 mg for men. In some cases, your doctor may recommend for you to take more than this daily. Speak with your doctor about adding a zinc supplement to your diabetes care plan.
Low-dose zinc supplementation (<25 mg/d) significantly benefited fasting blood glucose, insulin resistance, triglycerides, total cholesterol, and LDL cholesterol. High-dose zinc supplementation (≥25 mg/d) benefited glycated hemoglobin and insulin resistance.
Among them, the minerals zinc, potassium, calcium, and magnesium are considered essential for the homeostasis of glucose metabolism [5,7,8].
Magnesium helps regulate hundreds of body systems, including blood pressure, blood sugar, and muscle and nerve function. We need magnesium to help blood vessels relax, and for energy production, and bone development.
Interactions between your drugs
No interactions were found between metformin and Zinc.
The reported zinc deficiency in diabetic patients in different studies was explained by multiple theories. Zinc plays an important role in glucose and lipid metabolism. It decreases glucose absorption and synthesis, while promotes glucose metabolism and storage.
They can work together, boosting and enhancing absorption, or sometimes work against each other, competing for absorption. Zinc and magnesium are synergistic minerals that work together when taken at the right dosages.
Can Magnesium And Zinc Be Taken Together? Absolutely! In fact, they should be taken together. Minerals and vitamins are all competing for your body's ability to absorb them, so they need certain conditions for the best effect.
Can I take magnesium and zinc together? Yes! All minerals and vitamins are in competition, in that they need the right conditions for your body to absorb them properly. Some minerals have mutual benefits, while some only counteract each other's level of absorption (known as bioavailability).
Magnesium supplements should be taken with meals. Taking magnesium supplements on an empty stomach may cause diarrhea.