Caught early, the disease has a nearly 100 percent cure rate. But melanoma can come back. Risk of recurrence depends on thickness of the tumor that was removed; whether the layer of skin over the tumor was broken; whether surrounding lymph nodes are involved; and the speed of cancer cell growth.
Melanoma is the most invasive skin cancer with the highest risk of death. While it's a serious skin cancer, it's highly curable if caught early. Prevention and early treatment are critical, especially if you have fair skin, blonde or red hair and blue eyes.
Because stage IV melanoma is often hard to cure with current treatments, patients may want to think about taking part in a clinical trial. Many studies are now looking at new targeted drugs, immunotherapies, chemotherapy drugs, and combinations of different types of treatments.
If a tumor penetrates deeper, into the dermis, it is considered invasive (stages I and II). On average, the estimated five-year survival rate for melanomas detected while still localized is very high: about 99 percent in the U.S.
Survival for all stages of melanoma
around 90 out of every 100 people (around 90%) will survive their melanoma for 5 years or more after diagnosis. more than 85 out of every 100 people (more than 85%) will survive their melanoma for 10 years or more after they are diagnosed.
At 15 years and 20 years after diagnosis, respective melanoma-specific survival rates were 96.7% and 96.0%, with no significant (P = . 23) variation according to period of diagnosis (Table 1). Females had a better survival than males overall (P < .
The 5-year survival rate is around 92%. The 10-year survival rate is around 86%.
How fast does melanoma spread and grow to local lymph nodes and other organs? “Melanoma can grow extremely quickly and can become life-threatening in as little as six weeks,” noted Dr. Duncanson. “If left untreated, melanoma begins to spread, advancing its stage and worsening the prognosis.”
Melanoma is most likely to return within the first 5 years of treatment. If you remain melanoma free for 10 years, it's less likely that the melanoma will return. But it's not impossible. Studies show that melanoma can return 10, 15, and even 25 years after the first treatment.
After you finish treatment, your dermatologist (or oncologist) will still want to see you regularly. Melanoma can return or spread after treatment. If this happens, it's most likely to occur within the first 5 years. During the first 5 years, you'll need thorough check-ups.
Doctors have known for decades that melanoma and many other cancer types tend to spread first into nearby lymph nodes before entering the blood and traveling to distant parts of the body.
Melanoma is an aggressive cancer that can spread quickly. Immunotherapy is cancer treatment that enhances your immune system's ability to destroy melanoma cells and prevent their spread. These therapies are key in treating advanced melanoma to help prevent its spread — and even provide a cure, in some cases.
Melanoma can go away on its own. Melanoma on the skin can spontaneously regress, or begin to, without any treatment. That's because the body's immune system is able launch an assault on the disease that's strong enough to spur its retreat.
Level 1: Melanoma is confined to the epidermis (the outer layer of the skin). Level 2: Melanoma has invaded the papillary dermis (the outermost layer of the dermis, the next layer of skin). Level 3: Melanoma has invaded throughout the papillary dermis and is touching on the next, deeper layer of the dermis.
For some people, the melanoma may never go away completely. These people may get regular treatment with immunotherapy, targeted therapy, chemotherapy, or other treatments to try to help keep the cancer under control for as long as possible.
How common is melanoma? The American Cancer Society's estimates for melanoma in the United States for 2023 are: About 97,610 new melanomas will be diagnosed (about 58,120 in men and 39,490 in women). About 7,990 people are expected to die of melanoma (about 5,420 men and 2,570 women).
Among all people with melanoma of the skin in the United States, from the time of initial diagnosis, the 5-year relative survival rate is 94%. The survival rates for melanoma vary based on several factors. These include a person's age and general health, and how well the treatment plan works.
Melanoma is often considered a disease of older people, since about half of melanomas occur in people over the age of 50, with the median age at diagnosis being 59. While older adults are at higher risk of developing melanoma, the incidence of melanoma is rapidly rising in young adults.
Melanoma is much less common than some other types of skin cancer. But melanoma is more dangerous because it's much more likely to spread to other parts of the body if not caught and treated early.
In fact, the youngest recorded death from melanoma was at 2 years of age, and there have been cases where Melanoma has been passed to an unborn child from maternal Melanoma deposits in the placenta. This is extremely rare but can result in a child actually being born with Melanoma.
Population-based studies indicate that only about 8%–18% of patients are diagnosed with a second primary melanoma.
Prognosis: Stage 0 melanoma, or melanoma in situ, is highly curable. There is very little risk for recurrence or metastasis. The 5-year survival rate as of 2018 for local melanoma, including Stage 0, is 98.4%.
Melanoma is usually curable when detected and treated early. Once it has spread deeper into the skin or other parts of the body, it becomes more difficult to treat and can be deadly. The estimated five-year survival rate for U.S. patients whose melanoma is detected early is about 99 percent.