As you can see, both Nexgard and Simparica are extremely good and effective flea and tick treatment and they do not have a major difference between them. But that being said, Simparica does kill an additional tick specie and is relatively faster in eliminating fleas and ticks.
The main differences between the two are the strength and speed at which the products work, with Simparica killing fleas in little as 3 hours and ticks within 8. Nexgard offers a 4 hour time frame for killing fleas while killing ticks in 24 hours.
Bravecto kills many types of ticks including the lone star tick for 8 weeks. Simparica's active ingredient, Sarolaner, begins to kill fleas within 3 hours and ticks within 8 hours. When considering time to efficiency between these two, we'll consider it a tie.
Different products are helpful against different types of pests. Some kill fleas, mites, heartworms, and mosquitoes. However, if your goal is to target fleas and ticks, Nexgard is recommended by most veterinarians!
Simparica is an excellent choice for flea and tick protection. The monthly chew also comes with an option for heartworm protection, too, as Simparica Trio. But while Simparica is usually safe flea and tick treatment for dogs, it shouldn't be prescribed to dogs with a history of seizures.
Simparica Trio is considered safe for dogs as young as eight weeks old who weigh at least 2.8 pounds. However, the product has not been evaluated in breeding, pregnant, or lactating dogs.
The only downside to NexGard is that the parasites have to bite the dog to be affected by the medication, which can sometimes take several hours to take place. We'll contact your Vet to verify.
A Pesticide That Targets the Central Nervous System
Isoxazolines are neurotoxic to more than just insects; they also affect mammals. There is a reason why so many dogs experience seizures, ataxia, and tremors after taking NexGard — the pesticide compromises the dog's central nervous system.
Nexgard Spectra is a multicoverage product that protects against all common parasites (it is not the same as Nexgard Flea and Tick!). Nexgard Spectra does not protect against tapeworm.
Cedar oil is a good replacement for flea medications for dogs like Bravecto Chews for Dogs, Frontline Plus for Dogs, Revolution for Dogs, Simparica for Dogs, Advantage Multi for Dogs, and more.
How does Simparica Trio work? Simparica contains three active substances: sarolaner, moxidectin and pyrantel. Sarolaner acts as an 'ectoparasiticide'. This means that it kills parasites present on the skin or in the fur of animals, such as fleas and ticks.
Simparica is safe and effective in the treatment and prevention of flea infestations.
There are three drugs in the category of chewable flea and tick preventives: Nexgard, Bravecto and Simparica. Nexgard (active ingredient afoxolaner) and Bravecto (fluralaner) were approved in the US in late 2013 and early 2014. Simparica (sarolaner) came out in March 2016.
Simparica flea and tick medicine are proven to be 96.9 percent effective at killing fleas and ticks in dogs, and it starts working in three to eight hours after the first tablet. If your dog has a flea infestation, the medication will kill the existing fleas and prevent new infestations on your pet.
Yes, Nexgard is an incredibly safe and effective prevention for fleas, ticks, and mites. However, because Nexgard is ingested and absorbed into the bloodstream, rather than applied to and spread by the oils of the skin, the few reactions that do occur can seem more dramatic.
Protecting your puppy against worms is also crucial. Nexgard Spectra is an excellent all-around wormer using the active ingredient Milbemycin Oxime that protects against gut worms, lungworm disease, eye worms, hookworms, whipworms, roundworms and perhaps the most important, heartworms.
Causes of NexGard reactions in dogs are primarily due to a reaction to the active ingredient, afoxolaner. Specific causes include: The hypersensitivity towards the main ingredient.
NexGard SPECTRA contains an additional active ingredient, milbemycin oxime, which provides protection against heartworm and intestinal worms. With two active ingredients, NexGard SPECTRA provides the most complete protection against fleas, ticks, mites, heartworm disease and intestinal worms, all in one tasty chew.
NexGard® Recalls & Controversies
Although there have not been any FDA recalls for NexGuard®, the FDA has put out an alert for pet owners and veterinarians. This is because there is potential for neurological adverse events in dogs and cats when they are treated with drugs that fall into the isoxazoline class.
NexGard kills fleas within 8 hours and ticks within 48 hours. After being given, its actions last for at least 5 weeks against fleas and up to one month against ticks.
If you miss that monthly dose, your pet is at a potential risk of getting flea or tick bites, which can transmit some serious diseases. Heartworm preventive medicine is especially important to keep on schedule for your pet.
Best Overall: Frontline Plus Topical Treatment
The most frequently recommended is a topical treatment. Frontline Plus is a well-established product: “For more than 20 years, veterinarians and pet owners have been using Frontline Plus for Dogs to effectively prevent, treat, and control fleas,” writes DogProductPicker.
Among the best flea treatments for dogs, Frontline Plus is our top nonprescription recommendation because it kills ticks and fleas, controls flea infestations, and kills chewing lice, all with one easy application. When used primarily for flea control, each dose of Frontline Plus lasts up to three months.
NexGard is a safe and effective treatment for infestations of fleas and ticks, killing them before they have chance to lay their eggs. The treatment can be used in puppies from the age of eight weeks and in dogs weighing over 4 lbs.