These popular drugs were already linked to short-term kidney problems, but newer studies on Nexium, Prilosec and Prevacid show a link between PPIs and chronic, long-term kidney disease. More frequent use of PPIs can increase the risk of serious kidney injury.
Increased chance of chronic kidney disease: It has not been proven that PPI use causes chronic kidney disease, but some studies suggest there is an increased risk of chronic kidney disease in individuals who have normal kidney function before using a PPI.
Patients taking PPIs 28.4 times more likely to develop chronic kidney disease. People taking protein pump inhibitors (PPIs) such as omeprazole (Prilosec), esomeprazole (Nexium) and lansoprazole (Prevacid) have a higher risk of developing kidney disease, a new study says.
PPIs may trigger acute interstitial nephritis, a potentially severe adverse event commonly associated with acute kidney injury. Studies have found that prolonged use of PPIs may increase the risk of chronic kidney disease (CKD).
NSAIDs, diuretics, and ACE inhibitors are potential drugs that cause kidney damage. Certain medications administered in hospital settings, like aminoglycoside antibiotics and vancomycin, can also damage the kidneys.
Magnesium salts (applies to Gaviscon Extra Strength) renal dysfunction. Major Potential Hazard, High plausibility. Magnesium is eliminated by the kidney. The serum concentration of magnesium is increased in patients with renal impairment.
Tolerance and safety were good and comparable in both groups. Conclusion Gaviscon® was non-inferior to omeprazole in achieving a 24-h heartburn-free period in moderate episodic heartburn, and is a relevant effective alternative treatment in moderate GERD in primary care.
Best choices
Calcium carbonate (Tums® Antacid) › You may also need this for phosphate binding.
Recent global studies on anti-acidity pills — popped for treating “gas” and heartburn — have pointed out that there can be serious adverse events due to their prolonged use like long-term kidney damage, acute renal disease and chronic kidney disease, and in certain cases, even gastric cancer.
Sometimes, if Gaviscon does not work or agree with you, your doctor or pharmacist may suggest another reflux suppressant. Like Gaviscon, you can buy Peptac or Acidex from pharmacies and supermarkets. Are there other indigestion medicines?
Nexium, Prilosec, Pepcid and Tums are all considered well tolerated medications. Most people do not experience side effects from taking them, but it is possible to experience constipation or diarrhea, nausea, vomiting, headaches, rash or dizziness in some cases.
If you have allergies to any medications or medication ingredients, especially if they're in esomeprazole or other PPIs. If you take blood thinners, methotrexate, HIV medications, antifungal drugs or any other medications that may interact with Nexium. If you take vitamins or supplements, including St. John's Wort.
Proton pump inhibitors (such as esomeprazole) may increase your risk for bone fractures, especially with longer use, higher doses, and in older adults. Talk with your doctor or pharmacist about ways to prevent bone loss/fracture, such as by taking calcium (such as calcium citrate) and vitamin D supplements.
The concerns around their extended use are that they may lead to increased risk of bone fractures, vitamin B and magnesium deficiencies, and infection with Clostridium difficile bacteria, which can cause serious bowel damage and in some vulnerable people, lead to an increased risk of premature death.
The lowdown
While plain water is the best drink for your kidneys, other fluids are perfectly acceptable, including coffee, green tea, low-potassium juices, and infused water. Avoid sweetened, carbonated beverages and coconut water.
Water: Water is simply the best drink you can have! Water is a zero-calorie, perfectly hydrating, cheap drink. If you are in the earlier stages of kidney disease, choosing water most of the time to quench your thirst will keep your body and kidneys functioning well.
Lemon Juice
Lemon juice is naturally acidic and increases citrate levels in urine, hence discouraging the formation of kidney stones. Lemon juice also filters blood and flushes out wastes and other toxins.