The most common side effects of Ozempic, according to the drug's website, are nausea, stomach pain, constipation, diarrhea and vomiting. Novo Nordisk, the maker of Ozempic and Wegovy, told CBS News that the drugs "are a well-established class of medicines, which have demonstrated long-term safety in clinical trials.
This drug has a boxed warning about possible risk of thyroid cancer. This is the most serious warning from the Food and Drug Administration (FDA). A boxed warning alerts doctors and patients about drug effects that may be dangerous. In animals, Ozempic can increase the risk of thyroid tumors.
A person can stay on Ozempic® so long as they are tolerating the medication and it is deemed appropriate by their treating provider. There is no specific time frame when someone should stop taking Ozempic as it is a medication that is intended for chronic (long-term) use.
The most common side effect with Ozempic is nausea and occurs in about 15% to 20% of people. Others include vomiting (5% to 9%), diarrhea (8%), stomach-area pain (6% to 7%), and constipation (3% to 7%).
Ozempic® lowers fasting and postprandial blood glucose by stimulating insulin secretion in a glucose-dependent manner.
The most common side effects of Ozempic, according to the drug's website, are nausea, stomach pain, constipation, diarrhea and vomiting. Novo Nordisk, the maker of Ozempic and Wegovy, told CBS News that the drugs "are a well-established class of medicines, which have demonstrated long-term safety in clinical trials.
You start feeling those usual hunger pangs again, and consequently, you may start eating more to satisfy that hunger. An increase in your consumption can lead to the regaining of weight that was lost. A 2022 study found that most individuals gain weight back a year after stopping the medication.
Semaglutide (Ozempic, Wegovy, Rybelsus) can cause side effects that some people are unable to tolerate. Following dosing guidelines can help manage these side effects. Nausea, vomiting, and diarrhea are the most common semaglutide side effects. But they usually subside after a few weeks of using the medication.
If you stop taking Ozempic, the weight you lost will likely return, fast. People who ceased use of semaglutide gained back, on average, a full two-thirds of the weight they had lost on the drug within one year, according to an August 2022 study, the Wall Street Journal reports.
“There's a warning here: You take this drug and you lose a lot of weight. But you need to stay on it for the rest of your life.
Ozempic and its sister medication, Wegovy — approved for weight loss for people who are obese or overweight with weight-related medical conditions — are considered long-term or lifelong treatments.
Patients speak out over side effect claim that Ozempic poses risk of "stomach paralysis", and investigations into the prescription drug are showing possible signs of suicidal thoughts in users.
Thanks to a number of scientific studies, we know that Ozempic is an effective medication for medical weight loss. And, for those who have struggled with their weight for years, Ozempic can help people achieve impressive weight loss outcomes and improve their health in the long term.
The most common side effects when using Ozempic® are diarrhoea and nausea. These side effects are usually mild and normally decrease with continued use. Speak to your doctor if you have any of these less serious side effects and they worry you.
In combination with lifestyle changes like diet and exercise, Ozempic may also be prescribed off-label for weight management in people with obesity and overweight. Gastrointestinal side effects from Ozempic are common, but manageable. They include nausea, vomiting, diarrhea, abdominal pain, and constipation.
For people with type 2 diabetes who take Ozempic to manage their blood sugar, halting treatment may cause blood sugar to rebound to around pre-medication levels, says Beverly Tchang, MD, an endocrinologist and an assistant professor at Weill Cornell Medicine in New York City.
In rare cases, the use of Ozempic may cause anxiety and mood swings, irritability, shakiness, and confusion. However, when you take other medications along with Ozempic, it may escalate anxiety or mood change.
Stopping Ozempic
Meanwhile, these are “not medications that our body becomes addicted to, there are no significant withdrawals and no significant major rebound effects,” emphasized Dr. Warriner. In her patients with diabetes, Warriner has also observed a return of increased appetite over time.
Studies have similarly shown weight rebound in people who stop taking Ozempic. She said it's tied to how the drugs work. They mimic a hormone produced in the gut called GLP-1, which signals to the brain when a person is full.
In short, there is nothing inherently dangerous about taking Ozempic if you do not have diabetes (it does not work like insulin, which can be deadly if someone without diabetes takes it), but there is no final say on whether it is safe or not.