Epidemiological studies show that exposure to early stress in the form of abuse and neglect in childhood increases the risk to later develop schizophrenia (Bonoldi et al., 2013).
Research suggests that schizophrenia occurs due to a combination of genetic and environmental factors, which can cause abnormal development in the brain. In people with these risk factors, severely stressful life events, trauma, abuse, or neglect may trigger the condition.
Contrary to the beliefs of professionals prior to the 1970s and to the impression still promoted by the popular media, there is no evidence, even after decades of research, that family or parenting problems cause schizophrenia.
Earlier this year, psychiatrists at Harvard University found that being sexually or emotionally abused as a child correlated with reduced volumes of three important areas of the hippocampus, which is involved in the control of memory and regulation of emotions.
Past studies have reported that offspring of affected mothers have a higher risk of schizophrenia than the offspring of affected fathers; however, other studies found no such maternal effect [Gottesman and Shields, 1976].
Stressful life events
Highly stressful or life-changing events may sometimes trigger schizophrenia. These can include: being abused or harassed. losing someone close to you.
There are studies that show the experience of trauma in childhood, whether or not it develops into PTSD, is a risk factor for schizophrenia and psychosis later in life. An extensive review of 27,000 studies has definitively confirmed that trauma puts people at risk for psychotic conditions and symptoms.
It's not known what causes schizophrenia, but researchers believe that a combination of genetics, brain chemistry and environment contributes to development of the disorder.
Previous research suggests that exposure to childhood abuse in particular may be an important risk factor for the development of psychotic disorder.
It is widely accepted that early life experience, trauma, abuse and deprivation greatly increase the risk of developing psychosis.
Schizophrenia usually involves delusions (false beliefs), hallucinations (seeing or hearing things that don't exist), unusual physical behavior, and disorganized thinking and speech. It is common for people with schizophrenia to have paranoid thoughts or hear voices.
Unfortunately, most people with schizophrenia are unaware that their symptoms are warning signs of a mental disorder. Their lives may be unraveling, yet they may believe that their experiences are normal. Or they may feel that they're blessed or cursed with special insights that others can't see.
In some people, schizophrenia appears suddenly and without warning. But for most, it comes on slowly, with subtle warning signs and a gradual decline in functioning, long before the first severe episode. Often, friends or family members will know early on that something is wrong, without knowing exactly what.
Schizophrenia has been described as the “worst disease” to afflict mankind. It causes psychosis, which is an abnormal state of mind marked by hyperarousal, overactivation of brain circuits, and emotional distress. An untreated episode of psychosis can result in structural brain damage due to neurotoxicity.
Most people with schizophrenia make a recovery, although many will experience the occasional return of symptoms (relapses). Support and treatment can help you to manage your condition and the impact it has on your life.
Although some people with schizophrenia suffer anxiety, it is impossible for people with anxiety disorders to develop schizophrenia as a result of their anxiety disorder. Anxiety sufferers should be reassured that they cannot develop schizophrenia as part of their anxiety state, no matter how bad the anxiety becomes.
Anxiety and affective symptoms are prominent features of schizophrenia which are often present in the prodromal phase of the illness and preceding psychotic relapses. A number of studies suggest that genetic risk for the disorder may be associated with increased anxiety long before the onset of psychotic symptoms.
In most people with schizophrenia, symptoms generally start in the mid- to late 20s, though it can start later, up to the mid-30s. Schizophrenia is considered early onset when it starts before the age of 18. Onset of schizophrenia in children younger than age 13 is extremely rare.
The risk for schizophrenia has been found to be somewhat higher in men than in women, with the incidence risk ratio being 1.3–1.4. Schizophrenia tends to develop later in women, but there do not appear to be any differences between men and women in the earliest symptoms and signs during the prodromal phase.
Results: In patients with schizophrenia, MR imaging shows a smaller total brain volume and enlarged ventricles. Specific subcortical regions are affected, with reduced hippocampal and thalamic volumes, and an increase in the volume of the globus pallidus.
Newman adds that with support, parents with schizophrenia can provide for their children by working, as well as teaching and loving them just like parents without mental health conditions.
Borderline schizophrenia is held to be a valid entity that should be included in the DSM-III. It is a chronic illness that may be associated with many other symptoms but is best characterized by perceptual-cognitive abnormalities. It has a familial distribution and a genetic relationship with schizophrenia.