The active component of turmeric is curcumin, a polyphenolic phytochemical, with anti-inflammatory, antiamyloid, antiseptic, antitumor, and antioxidative properties. Curcumin was reported to have antiallergic properties with inhibitory effect on histamine release from mast cells.
Summary. Natural antihistamines may help you control your seasonal allergies. Common ones are stinging nettle, vitamin C, quercetin, butterbur, bromelain, and probiotics. Some alternative practices—such as acupuncture, nasal irrigation, and exercise—may also help you manage symptoms.
Turmeric is a common, yellow-orange spice that's derived from the turmeric plant. It's often used in Asian dishes and can do wonders for your allergies. Due to curcumin, its primary ingredient, turmeric can reduce the swelling and irritation of allergic rhinitis.
Nettles. Nettle leaf is a natural antihistamine that naturally blocks histamine production. It can be made in to a tincture or tea, but for allergy relief, capsules made from dried nettle leaves are the most effective option.
With regard to second-generation H1-antihistamines, there are many efficacious and safe drugs on the market for the treatment of allergic disease. Of the 3 drugs highlighted in this review, levocetirizine and fexofenadine are the most potent in humans in vivo.
OTC antihistamines include: Brompheniramine (Dimetane) Cetirizine (Zyrtec) Chlorpheniramine (Chlor-Trimeton)
Turmeric is likely suitable for a low histamine diet. Turmeric is likely low in histamine and other amines and does not trigger release of the body's natural histamine. Every person has unique dietary triggers.
No interactions were found between Benadryl and turmeric. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Effective doses
Studies typically use doses of 500–2,000 mg of turmeric per day, often in the form of an extract with a curcumin concentration that is much higher than the amounts naturally occurring in foods.
Vitamin C is a natural antihistamine, which means it can lower histamine levels and mitigate allergic reactions and symptoms. Consume plenty of Vitamin C rich foods, like tropical fruits, citrus fruits, broccoli and cauliflower, and berries.
Allergists recommend long-acting, non-sedating antihistamines — ones that won't make you sleepy — for everyday use. Though you may know them by their brand names, the generic versions tackle the same problems: Cetirizine (Zyrtec®, Aller-Tec®, Wall-Zyr®). Fexofenadine (Allegra®, Aller-ease®, Aller-Fex®, Wal-Fex®).
The best way to clear histamine from the body is to start an elimination diet that involves only eating and drinking substances that contain low amounts of histamine.
Cetirizine has the fastest onset of action among the newer antihistamines. Fexofenadine does not impair psychomotor or cognitive skills and shows no dose-related increase in sedation but has a slower onset of action than diphenhydramine and cetirizine.
Citrus Fruits – Vitamin C (ascorbic acid) is an antioxidant that prevents oxidative stress in the body and is also a natural antihistamine. Consuming adequate amounts of Vitamin C from citrus fruits such grapefruits, oranges, lemons and kiwis can also help fight infections.
High doses of turmeric could have a blood-thinning effect; if taken on top of prescribed anticoagulants, this could increase the risk of dangerous bleeding. People with liver or bile duct problems should not take turmeric supplements, as they can increase bile production.
Don't take turmeric supplements if:
You're taking aspirin, ibuprofen (Advil , Motrin ), or Acetaminophen (Tylenol ). Turmeric may lessen the effects of these medications.
Turmeric should be taken with meals to help with absorption. It's also a good idea to divide it into two doses taken 8 to 12 hours apart. This will help increase absorption and keep levels steady in the body. Dividing the dose may also help reduce possible side effects.
Several groups have reported that curcumin shows anti-allergic activity through the inhibition of histamine release, TNF-α and IL-4 from activated mast cells and in vivo type I hypersensitivity animal model (Yano et al., 2000; Ram et al., 2003; Lee et al., 2008).
Phenbenzamine (Antergan) was the first clinically useful antihistamine and was introduced for medical use in 1942.
Chlorpheniramine is the main active ingredient in Chlor-Trimeton. It helps relieve runny nose, sneezing, itchy or watery eyes, and nose and throat itching from hay fever. It also helps relieve other respiratory allergies.
Pros: Zyrtec is a renowned antihistamine that's known for performing faster (“starts working at hour 1”) than some of its competitors. This makes it exceptionally useful if you're desperate for quick relief from common symptoms of allergic rhinitis (also known as hay fever), like a runny nose and watery eyes.