The condition probably results from a combination of genetic and environmental factors, many of which have not been identified. Studies suggest that psychological stress, exposure to ultraviolet radiation, or contact with certain chemicals or skin-whitening products may trigger vitiligo in predisposed individuals.
The inherited origin of vitiligo and its frequent association with autoimmune diseases suggest an association between HLA systems to vitiligo predisposition. The HLA loci are strongly linked to other loci in the major histocompatibility complex (MHC) region of chromosome 6p.
The fact that vitiligo is more common in family members of people with vitiligo means that genetics play a role in the disease. That's not too surprising, since genetics plays a role in most diseases, as well as normal traits (like hair color, height, etc). Dr.
What is known is that the risk of developing vitiligo increases in kids with a family or personal history of thyroid disease, diabetes, and certain conditions like alopecia (an autoimmune disease that causes hair loss). Vitiligo is never contagious — kids can't "catch" it from someone else.
Anyone can get vitiligo, and it can develop at any age. However, for many people with vitiligo, the white patches begin to appear before age 20, and can start in early childhood.
Triggers. It's possible that vitiligo may be triggered by particular events, such as: stressful events, such as childbirth. skin damage, such as severe sunburn or cuts (this is known as the Koebner response) hormonal changes to the body, such as puberty.
Generally speaking, there's no way to prevent the onset of vitiligo. While there is no cure, the goal of treatment is to minimize the spread of the condition. However, certain lifestyle changes can help you reduce your condition from worsening.
Children of probands are found to be afflicted about 1.7 times more commonly than other first-degree relatives. The relative risk (RR) for vitiligo is about 7 for parents, about 12 for siblings, and about 36 for children. For second-degree relatives, the RR varies between 1 and 16.
Inheritance. Vitiligo sometimes runs in families, but the inheritance pattern is complex because multiple causative factors are involved. About one-fifth of people with this condition have at least one close relative who is also affected.
However, it is not a rule that children of vitiligo parents will always have vitiligo. Relatively, the chance of the offspring having vitiligo may be somewhat higher if one or more of the parents have vitiligo. Vitiligo does not spread by touch or contact. It does not affect marriage life or physical relationship.
Vitiligo doesn't discriminate, and it is found relatively equally in all ethnicities and sexes. This article discusses important facts and statistics about vitiligo.
Who gets vitiligo? People of all races and skin colors can get vitiligo, and the disease occurs about equally in people of all races. About half the people who develop vitiligo get it before they turn 20 years of age. For many of these people, vitiligo begins when they're a child.
Researchers have identified several genes associated with vitiligo. In the sample report below, we've attempted to analyze some important genes that increase the risk of vitiligo. You can identify your genetic risk of vitiligo by using your 23andMe DNA data and placing an order for the Gene Health Report.
Conclusion: some hormonal indicators have a role in pathogenesis of vitiligo where their disturbance leads to melanocyte destruction and/or depigmentation. Vitiligo is an idiopathic disorder of skin and hair characterized by melanin loss.
The opposite of Vitiligo, Melasma is a hyperpigmentary disease.
Approximately 25 percent to 50 percent of those with vitiligo also have a relative with vitiligo, while 6 percent may have a sibling who has it as well. Some MyVitiligoTeam members have family members with the skin condition.
Effect of vitiligo on pregnancy outcomes
Psoriasis is also associated with definitive increased risks of recurrent miscarriages, chronic hypertension, and higher caesarean deliveries [1]. A recent retrospective cohort study from Taiwan indicated that women with vitiligo had a higher risk of miscarriages.
Vitiligo (pronounced: vittle-EYE-go) is a skin disorder that causes depigmentation (loss of skin color) in irregular patchy patterns. The disorder itself is rare, affecting only about 0.5% to 1% of the world's population.
Females tend to present with vitiligo at an earlier age, with a peak prevalence during the first decade of life, whereas male peak prevalence is in the fifth decade of life.
Usually, it starts in childhood or young adult: it has been estimated that about 50% of patients develop vitiligo before the age of 20 years and about 25% of them develop the disease before the age of 8, with a mean age of 4 - 5 years [2].
According to the American Academy of Dermatology Association, up to half of people who develop vitiligo do so before the age of 20. But despite its high incidence in childhood and early adulthood, vitiligo can happen at any age, says the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS).
Studies suggest that vitamin D3 increases tyrosinase activity and melanogenesis in vitro [12], which may lead to repigmentation in vitiligo skin lesions. Calcipotriol and tacalcitol, which are vitamin D analogs, are also known to induce repigmentation in patients with vitiligo [13,14].
It is thought that sunlight can be both good and bad for people with vitiligo, for several different reasons. For example, on the disadvantage side, some medical experts believe it's possible that sunburn could be a trigger for developing the skin condition.