Four disease courses have been identified in multiple sclerosis: clinically isolated syndrome (CIS), relapsing-remitting MS (RRMS), primary progressive MS (PPMS) and secondary progressive MS (SPMS).
Contents. You may have to adapt your daily life if you're diagnosed with multiple sclerosis (MS), but with the right care and support many people can lead long, active and healthy lives.
Disease Course of MS Is Unpredictable
A person with benign MS will have few symptoms or loss of ability after having MS for about 15 years, while most people with MS would be expected to have some degree of disability after that amount of time, particularly if their MS went untreated.
Mood changes
These feelings will likely ebb and flow over the course of the disease. Worry, fear, moodiness, irritability and anxiety: normal reactions in the face of unpredictability; anyone can become irritable and anxious when faced with difficult challenges. Depression: one of the most common symptoms of MS.
Outlook. The outlook for benign MS isn't clear. Some people who are diagnosed with it never go on to have a more serious disease progression, while others do. Remember, just because you have mild symptoms when you're first diagnosed with MS doesn't mean that they'll stay that way.
The early stages of MS - and finding out if, indeed, you do have MS - can be a worrying time. The process of diagnosis can take months, in some cases years, and is often referred to as 'limboland'.
CIS is often referred to as the first stage of MS, even though it doesn't meet the MS criterion for dissemination in time (MS damage that occurs on different dates). CIS is considered a monofocal episode when only one neurological symptom is present—for example, an attack of optic neuritis.
Here's where MS (typically) starts
You may experience eye pain, blurred vision and headache. It often occurs on one side and can eventually lead to partial or total vision loss. Spinal cord inflammation, or what's called partial transverse myelitis, is the second most common symptom Shoemaker typically sees.
Over time, more than two-thirds of people remain able to walk, although they may need an ambulation aid such as a cane or walker to do so. Some may choose to use a motorized scooter or wheelchair for long distances, in order to conserve energy and remain more active; others may need to use a wheelchair all the time.
Factors that may trigger MS include: Exposure to certain viruses or bacteria: Some research suggests that being exposed to certain infections (such as Epstein-Barr virus) can trigger MS later in life. Where you live: Your environment may play a role in your risk for developing MS.
Alcohol can exacerbate some symptoms of MS, such as those related to urinary frequency, depression, thinking, and balance. Alcohol can also interact with medications, affecting how they work or increasing the risk of adverse effects, such as liver damage.
It can cause symptoms like problems with vision, arm or leg movement, sensation or balance. It's a lifelong condition that can sometimes cause serious disability. In many cases, it's possible to treat symptoms. Average life expectancy is slightly reduced for people with MS.
Fatigue. Feeling fatigued is one of the most common and troublesome symptoms of MS. It's often described as an overwhelming sense of exhaustion that means it can be a struggle to carry out even the simplest activities.
These include fibromyalgia and vitamin B12 deficiency, muscular dystrophy (MD), amyotrophic lateral sclerosis (ALS or Lou Gehrig's disease), migraine, hypo-thyroidism, hypertension, Beçhets, Arnold-Chiari deformity, and mitochondrial disorders, although your neurologist can usually rule them out quite easily.
While there are no definitive blood tests for diagnosing MS, they can rule out other conditions that may mimic MS symptoms, including Lyme disease, collagen-vascular diseases, rare hereditary disorders, and acquired immune deficiency syndrome (AIDS).
The early signs and symptoms of MS can be the same for women and men. One of the more obvious first signs of MS is a problem with vision, known as optic neuritis. This is often because it's a more concrete symptom as opposed to vaguer neurological symptoms like numbness and tingling.
MS is a Silent Disease
For example, chronic pain, blurred vision, and sensory problems are only experienced by the individual with MS, and cannot be easily noticed by others.
Muscle spasms and stiffness: Formally called spasticity, this symptom can range from mild feelings of muscle tightness to severe and painful spasms, according to the National MS Society, and it most commonly affects the legs.
Constant fatigue is common for people with MS. This tiredness can impact all aspects of life, including effective brain use and the ability to go out and partake in activities. The symptoms of MS can cause constant discomfort and disability that limit a person's ability to go about daily activities.
Possible triggers include infections and stress, but there may also be no noticeable trigger. Anyone who notices a worsening of symptoms or that new symptoms appear should contact a doctor in case they need additional treatment or monitoring.
In relationships
People with MS and their partners tell us living with the condition can create both physical and emotional barriers, which can put a strain on relationships. For some couples, worries about MS and uncertainty about the future can cause a breakdown in communication and intimacy.