Since the release of NexGard, adverse events that have been reported for dogs are listed here in decreasing order of reporting frequency: Vomiting, pruritus, lethargy, diarrhea (with and without blood), anorexia, seizure, hyperactivity/ restlessness, panting, erythema, ataxia, dermatitis (including rash, papules), ...
Thank you for your question. I would not expect the lethargy or diarrhea to last more than 12-24 hours.
NexGard SPECTRA is safe for all breeds of dog when used as directed and can be given to puppies from 8 weeks of age, providing they weigh at least 2 kg.
NexGard® and NexGard SPECTRA® kill fleas by over-stimulating their nervous system, which results in uncontrolled activity of their nervous system and death. This occurs within 6-8 hours of product administration.
These products are safe to use in the majority of pets, but there are some pets that cannot tolerate the medication (specific liver disorders, pre-existing seizure disorders).
It is advised to be used with caution in dogs with a history of seizures, and the safe use of NexGard in pregnant, breeding, or lactating dogs hasn't been evaluated. NexGard was approved by the U.S. Food and Drug Administration (FDA) in 2013, meaning the FDA decided that the benefits of it outweigh the potential risks.
As with any oral medication, vomiting, diarrhea, allergic or neurological reactions can occur. While we take all adverse reactions very seriously, our doctors have actually seen less reactions with oral Nexgard than with other topical flea and tick prevention options.
NEXGARD® is recommended for use in dogs and puppies 8 weeks of age and older. FOR ANIMAL USE ONLY. NEXGARD® contains afoxolaner, an insecticide-acaricide for oral treatment and prevention of flea and tick infestations of dogs for one month following a single administration.
Isoxazolines are neurotoxic to more than just insects; they also affect mammals. There is a reason why so many dogs experience seizures, ataxia, and tremors after taking NexGard — the pesticide compromises the dog's central nervous system. Once this happens, there is often no way back.
NexGard is given as a tablet of the appropriate strength for the dog's bodyweight. NexGard kills fleas within 8 hours and ticks within 48 hours. After being given, its actions last for at least 5 weeks against fleas and up to one month against ticks.
Causes of NexGard reactions in dogs are primarily due to a reaction to the active ingredient, afoxolaner. Specific causes include: The hypersensitivity towards the main ingredient. An over-reactive immune system.
“NexGard (afoxolaner) is one of the isoxazoline class of parasiticides. Please do NOT use any of them again. There are now two isoxazoline-related class-action lawsuits in North America — one in Quebec and the other in New Jersey. The FDA finally has required warnings on the labels and product inserts.
Is Bravecto, NexGard, Simparica, Seresto and K9 Advantix II Safe for Australian Shepherds? Ultimately this is a question only you and your veterinarian can answer. According to the available FDA adverse reaction data, most pets do fine on these medications.
Bravecto Chew is also effective in killing adult fleas, so it can help reduce the risk of your dog getting flea bite dermatitis. If you're looking for a safe and effective flea and tick treatment for your dog, Bravecto Chew is the way to go.
According to the FDA, some animals receiving drugs in the isoxazoline class, including Bravecto, Nexgard and Simparica have experienced adverse events such as muscle tremors, ataxia, and seizures.
Nexgard can kill 99% of all infections in a single treatment. The product kills eggs, larvae, and full-grown parasites making it highly effective in protecting your dog's health.
Although there have not been any FDA recalls for NexGuard®, the FDA has put out an alert for pet owners and veterinarians.
In the US field study, one dog with a history of seizures experienced a seizure on the same day after receiving the first dose and on the same day after receiving the second dose of NexGard. This dog experienced a third seizure one week after receiving the third dose.
Both products are safe for dogs when following directions and have been approved by the FDA to treat and prevent flea and tick infestations. While Simparica was trialed and not approved, Nexgard has not yet been evaluated for use in breeding, pregnant, or lactating dogs.
Many flea and tick medications are manufactured in a once-monthly topical application or pill. If you miss that monthly dose, your pet is at risk of getting flea or tick bites.
Since the release of NexGard, adverse events that have been reported for dogs are listed here in decreasing order of reporting frequency: Vomiting, pruritus, lethargy, diarrhea (with and without blood), anorexia, seizure, hyperactivity/ restlessness, panting, erythema, ataxia, dermatitis (including rash, papules), ...
NexGard SPECTRA provides the most complete protection from fleas, ticks, mites, heartworm and intestinal worms, all in one tasty chew. How often should NexGard SPECTRA be given? You should dose your dog once a month, ideally on the same day of each month.
Isoxazoline products have been associated with neurologic adverse reactions, including muscle tremors, ataxia, and seizures in some dogs and cats. Although most dogs and cats haven't had neurologic adverse reactions, seizures may occur in animals without a prior history.
The small percentage of ticks that do land on your dog's fur are immediately affected by the medication and are unable to walk or attach to the skin. Within minutes, the ticks fall off your dog and die, rendering them unable to affect your family or other pets.
Dog flea collars, topical treatments, and oral medications are commonly recommended. Examples include the Seresto collar for long-lasting protection and Frontline Plus for flea and tick prevention. Oral medications like Simparica and Bravecto offer convenience and effectiveness.