Avoid first-generation antihistamines.
The side effects—possible anxiety, confusion, drowsiness, urine retention, dry mouth and eyes, and dizziness—make these drugs inappropriate for seniors.
The drowsiness and fatigue which may occur in a small percentage of patients may be more of a problem for the elderly because of the increased risk of bone fracture if they fall. Other medical problems common in elderly patients may contribute to sedation.
The most commonly reported side effects include somnolence, dizziness, and headache. Use these dosage charts for infants and children under 12 years old: Zyrtec Dosage Charts (Infants & Children)
So what can older adults safely take for allergy relief? Wozniak: Newer antihistamines such as Claritin® (loratadine) and Allegra® (fexofenadine) tend to be safer and better tolerated.
You should not use Zyrtec-D if you have narrow-angle glaucoma, severe high blood pressure (hypertension), severe coronary artery disease, if you are unable to urinate, or if you are allergic to hydroxyzine (Atarax, Vistaril). Do not use this medicine if you have taken an MAO inhibitor in the past 14 days.
Second-generation antihistamines are effective in elderly patients with allergic rhinitis in drops and oral forms.
Is it safe to take Zyrtec every day? Yep. "When taken in the recommended doses, antihistamines can be taken daily. This is especially true with Zyrtec, since it doesn't show decreasing effectiveness if used daily," says Sima Patel, MD, an allergist at New York Allergy & Sinus Centers.
Rarely, they can cause acute self-limited liver injury. One study has reported a more serious long-term effect, a 3.5-fold increase in the risk of gliomas, a common type of brain tumor in patients with long-term antihistamine use for allergic conditions.
What's the best time of day to take ZYRTEC®? Any time of day works. And ZYRTEC® will continue to work for 24 hours.
ZYRTEC-D® Allergy Relief Tablets with Decongestant and Cetirizine HCl. Adults under 65 and children 12 years and older One 10 mg capsule once daily; do not take more than one 10 mg capsule in 24 hours. Adults 65 years and over Ask a doctor. Adults with liver or kidney disease Ask a doctor.
Antihistamines like diphenhydramine (Benadryl) and cetirizine (Zyrtec) aren't known to raise blood pressure when used alone. Antihistamines are part of many combination over-the-counter (OTC) cough and cold products. They may be combined with a medication that can raise your blood pressure.
For allergies, don't use under 2 years of age. Reason: not FDA approved. For age 2 - 6 years, talk with your child's doctor before using. For colds, not advised at any age.
See your doctor if your mild allergy symptoms have not improved after three days of treatment with Zyrtec, or if your hives persist for more than six weeks despite taking Zyrtec. Discontinue Zyrtec once your allergy symptoms have resolved.
Do not use with any other antihistamines applied to the skin (such as diphenhydramine cream, ointment, spray) because increased side effects may occur. Cetirizine is very similar to hydroxyzine and levocetirizine. Do not use these medications while using cetirizine.
Zyrtec may interact with other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety).
Yes, you can take cetirizine (Zyrtec) only when you need it if you have allergy symptoms once in a while. But if you have allergy symptoms on a daily basis, taking it regularly according to the manufacturer's directions might give you the most relief from your allergies.
Common side effects of H-2 antihistamines include:
Joint or muscle pain. Headache.
These common side effects include sedation, impaired motor function, dizziness, dry mouth and throat, blurred vision, urinary retention and constipation. Antihistamines can worsen urinary retention and narrow angle glaucoma. The antihistamines rarely cause liver injury.
The main withdrawal symptom is called pruritus— itching and burning sensations of the skin ranging from moderate to severe. Other antihistamine withdrawal symptoms include interruptions in sleep patterns.
Allergists recommend long-acting, non-sedating antihistamines — ones that won't make you sleepy — for everyday use. Though you may know them by their brand names, the generic versions tackle the same problems: Cetirizine (Zyrtec®, Aller-Tec®, Wall-Zyr®). Fexofenadine (Allegra®, Aller-ease®, Aller-Fex®, Wal-Fex®).
Appropriate studies performed to date have not demonstrated geriatrics-specific problems that would limit the usefulness of fexofenadine in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require an adjustment in the dose for patients receiving fexofenadine .