A new study from 2019 in the journal Science Advances showed that P. gingivalis, the bacterium that's a major cause of gum disease, is also linked to Alzheimer's. The DNA of P. gingivalis is present in the brain tissue and spinal fluid of patients with Alzheimer's.
gingivalis, the bacteria associated with periodontal disease (commonly known as gum disease) and Alzheimer's. Researchers analyzed brain tissue, spinal fluid, and saliva from Alzheimer's patients—both living and deceased—and found evidence ofP. gingivalis.
A species of bacteria called Porphyromonas gingivalis can travel from infections in the mouth through the bloodstream to the brain. Once in the brain, the bacteria release enzymes called gingipains that can destroy nerve cells, which in turn can lead to memory loss and eventually Alzheimer's.
nucleatum-related periodontal disease leads directly to Alzheimer's disease, the new study suggests that periodontal disease caused by F. nucleatum and left untreated or poorly treated could exacerbate symptoms of Alzheimer's disease, Chen believes.
Most people believe that dementia is the cause for improper oral hygiene in older adults. However, given the strong evidence, it's possible that gum disease from improper oral hygiene increases chances of developing Alzheimer's disease and/or dementia.
Age. Increasing age is the greatest known risk factor for Alzheimer's disease. Alzheimer's is not a part of normal aging, but as you grow older the likelihood of developing Alzheimer's disease increases.
Alzheimer's disease is thought to be caused by the abnormal build-up of proteins in and around brain cells. One of the proteins involved is called amyloid, deposits of which form plaques around brain cells. The other protein is called tau, deposits of which form tangles within brain cells.
Treatment procedures of P. gingivalis–mediated diseases such as periodontitis and peri-implantitis focus on the eradication of oral pathogens at the site of infection, usually by surface debridement procedures followed by adjunctive therapies, including the use of antiseptics or/and antibiotics [61–66].
Researchers have found a possible link between oral health and Alzheimer's disease. With this new knowledge, it's more important than ever to maintain good oral hygiene, especially flossing. This may help you prevent Alzheimer's disease, along with other health issues like diabetes and heart disease.
Toxic causes of dementia include exposure to heavy metals such as lead, mercury and aluminum as well as to carbon monoxide and solvents.
How Oral Bacteria Leads to Dementia. A recent study by NIA scientists showed that the bacteria that cause gum disease is associated with the development of dementia, including Alzheimer's disease. There are multiple types of dementia, with Alzheimer's accounting for 60–70% of all dementia cases.
Alzheimer's Amyloid Plaque Removal May Be Aided By Vitamin D And Omega 3. In a small pilot study, a team of US researchers has discovered how vitamin D3, a form of vitamin D, and omega 3 fatty acids may help the immune system clear the brain of amyloid plaques, one of the physical hallmarks of Alzheimer's disease.
A 2013 study from UC Santa Barbara implicated that cinnamon might be able to prevent the build up of tau protein tangles in the brains of people with Alzheimer's. Researchers extracted two chemicals from cinnamon — cinnamaldehyde and epicatechin — and used them to treat lab-created cells as part of the experiment.
The causes of most cases of Alzheimer's are currently unknown, but there is growing evidence to suggest microbial organisms are involved, in particular, herpes simplex virus type 1 (HSV-1), the so-called cold sore virus.
According to a U.S. study done in 2012 by the University of California, people who keep their teeth and gums healthy with regular brushing may have a lower risk of developing dementia at a later age.
Family history is not necessary for an individual to develop Alzheimer's. However, research shows that those who have a parent or sibling with Alzheimer's are more likely to develop the disease than those who do not have a first-degree relative with Alzheimer's.
Physical activity. Doing regular physical activity is one of the best ways to reduce your risk of dementia. It's good for your heart, circulation, weight and mental wellbeing. You might find it difficult to start being more physically active, or worry it means doing an activity you don't enjoy.
There is a reliable test that can be done in any dental office to test for PG. It's called the Oral DNA test. It tests for the 11 different bacteria that cause periodontal disease, including PG.
gingivalis is a pathogen, then it would be expected to be detected in most subjects with disease and rarely detected in subjects who are periodontally healthy. However, in most previous studies, P. gingivalis has not been detected in the majority of subjects with disease.
Porphyromonas gingivalis, a prominent component of oral microorganism communities, is the main pathogen that causes periodontitis.
The risk of developing Alzheimer's or vascular dementia appears to be increased by many conditions that damage the heart and blood vessels. These include heart disease, diabetes, stroke, high blood pressure and high cholesterol.
A 2019 study published in Journal of Alzheimer's Disease, showed among 165 participants (45 with diagnosed neurodegenerative disease, 120 controls) a supine sleep position (on back, head at body level) for more than 2 hours per night increased the risk of dementia by almost four times (3.7 times greater).
Studies show that dementia risk is lowest in people who have several healthy behaviours in mid-life (aged 40–65). These behaviours include: ∎regular mental, physical and social activity ∎not smoking ∎drinking alcohol only in moderation ∎keeping a healthy diet.