It may also be recommended to avoid citrus fruits and juices (e.g., orange, grapefruit, lemon), milk and dairy products, and antacids during treatment with Hiprex, as these products may decrease the effectiveness of the medicine.
Hiprex may interact with carbonic anhydrase inhibitors, sulfa drugs, diuretics (water pills), or products containing aluminum, calcium, magnesium, sodium bicarbonate, potassium or sodium citrate, or citric acid (such as antacids, vitamin or mineral pills, urinary alkalinizers, and other medications).
Drugs and Foods to Avoid
This medicine works best in acidic urine. Drinking cranberry juice will help keep urine acidic. Avoid foods that lower the acid in your urine, such as nuts or milk and other dairy products.
Adults take 1 tablet twice daily. Children over 6 years take half to 1 tablet twice daily. You can take Hiprex with or without food, but should avoid using the following medications as they may make Hiprex less effective.
Bladder irritation and frequent urination
Large doses of methenamine hippurate (Hiprex) (higher than recommended) can cause bladder irritation, frequent and painful urination, protein in your urine, and blood in your urine.
Nausea, vomiting, diarrhea, abdominal cramps, and loss of appetite may occur. If any of these effects last or get worse, tell your doctor or pharmacist promptly. Painful or difficult urination may occur with methenamine, although less often.
Methenamine hippurate tablets are most effective in an acidic environment. Ural Effervescent Powder is a urinary alkaliniser and will make your urine less acidic, thus compromising the effectiveness of the methenamine hippurate tablets.
Hiprex is an antibacterial medicine that can be taken on a long-term basis to treat and prevent urinary tract infections (UTIs), for example, if you frequently get UTIs or if you have a catheter. Hiprex can be bought over-the-counter from pharmacies.
Hiprex may cause serious side effects including: painful urination, increased urination, blood in the urine, and.
Hiprex is a urinary antibacterial agent with a wide antibacterial spectrum covering both gram-positive and gram-negative organisms. Urinary antibacterial activity can be shown within 30 minutes of administration.
Notes for Professionals: Methenamine should theoretically not be administered concurrently with food or beverages that may alter urinary pH, such as milk products and most fruits.
Some products that may interact with this drug include: sulfonamide drugs (including sulfa antibiotics such as sulfamethizole), products that decrease the amount of acid in the urine (urinary alkalinizers such as antacids, sodium bicarbonate, potassium or sodium citrate, carbonic anhydrase inhibitors such as ...
Additionally, a number of common foods and drinks — artificial sweeteners, spicy foods, alcohol, coffee, acidic fruits, citrus, or caffeinated drinks — can irritate your bladder, and may worsen UTI symptoms — so you should steer clear of them if you have signs of a bladder infection.
Hiprex is used to prevent ongoing or recurrent urinary tract infections (UTIs). It works by causing your pee (urine) to be acidic and in this way discourages the growth of bugs. It is not effective for the treatment of UTIs but may be considered for preventing UTIs.
Hiprex should be started after you have finished treatment of your current UTI. It is important to let your health professional know if you are taking any other treatments or over-the-counter medicines for your UTI as some medicines may lessen the effectiveness of Hiprex if taken at the same time.
The recommended dose is one tablet twice a day. If you have a catheter your doctor may increase your dose to one tablet three times a day. Not for children aged under 6. Children aged 6 – 12 years the recommended dose is half a tablet (500mg) twice a day.
Recurrent UTIs (RUTI) are mainly caused by reinfection by the same pathogen. Having frequent sexual intercourse is one of the greatest risk factors for RUTIs. In a subgroup of individuals with coexisting morbid conditions, complicated RUTIs can lead to upper tract infections or urosepsis.
Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking hyoscyamine. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness.
Unnecessary use of Hiprex can lead to its decreased effectiveness and the development of antibiotic-resistant bacteria. You should not take Hiprex if you have kidney failure, severe liver insufficiency, or you are severely dehydrated.
The new antibiotic, called gepotidacin, is the first developed in more than 20 years to treat UTIs. It works by blocking enzymes the bacteria need to start multiplying in the body. UTIs happen to people of all ages, but are common and especially dangerous for frail, elderly people.
Plenty of fluid should be consumed while taking Hiprex. Your doctor may recommend drinking additional water and/or certain fruit juices (e.g., cranberry, plum, prune) and increased protein in the diet while taking Hiprex to ensure adequate hydration and acidity of the urine.
Ciprofloxacin (Cipro) or levofloxacin (Levaquin)
Healthcare providers usually save these antibiotics for more complicated or severe types of UTIs.
The dose of Hiprex is 1 tablet 2 times a day – every 12 hours is best. If you have a catheter your doctor may increase your dose to 1 tablet 3 times a day.
Unnecessary use of Hiprex can lead to its decreased effectiveness and the development of antibiotic-resistant bacteria.