Antibiotics: Taking magnesium supplements may reduce the absorption of quinolone antibiotics, tetracycline antibiotics, and nitrofurantoin (Macrodandin). Magnesium should be taken 1 hour before or 2 hours after taking these medications. Quinolone and tetracycline antibiotics include: Ciprofloxacin (Cipro)
In addition, the magnesium in supplements can interact with some types of antibiotics and other medicines. Check with your doctor or pharmacist if you're considering magnesium supplements, especially if you routinely use magnesium-containing antacids or laxatives.
High-fat foods in general may reduce the absorption of magnesium. The quality of fats in your diet appears to make a difference in how much magnesium you retain from the foods you eat, and how much is depleted.
Magnesium also reacts exothermically with most acids such as hydrochloric acid (HCl), producing the metal chloride and hydrogen gas, similar to the HCl reaction with aluminium, zinc, and many other metals.
Phytates in the diet bind to magnesium and impair its absorption. However the quantities present in normal diet do not affect magnesium absorption. Other dietary factors that are thought to affect magnesium absorption are oxalate, phosphate, proteins, potassium and zinc.
People with diabetes, intestinal disease, heart disease or kidney disease should not take magnesium before speaking with their health care provider. Overdose. Signs of a magnesium overdose can include nausea, diarrhea, low blood pressure, muscle weakness, and fatigue. At very high doses, magnesium can be fatal.
The time of day doesn't matter so much—it's the consistency of taking magnesium daily that matters most. While some recommend taking magnesium supplements right before bed (to calm your mind and nervous system, setting the stage for sleep), do what works best for you to ensure that it becomes a daily healthy habit.
Can you take vitamin D and magnesium together? Yes. In fact, it's probably best to take both together. Because so many people have low magnesium levels, vitamin D supplements on their own aren't very helpful for a large portion of the population.
If you are taking magnesium for its restful sleep benefits, taking it with dinner or the last meal of the day may be your best bet.
So, get enough vitamin D—just take it in the morning or afternoon. At night, take supplements that support sleep quality and muscle relaxation, like magnesium and melatonin (which you'll find in soothing, sippable Bulletproof Sleep Collagen Protein).
Combining multiple supplements or taking higher-than-recommended doses can increase the risk that they can cause harm, said Kitchin. "You really can't get toxic doses of nutrients through food, but you can absolutely get toxic doses through supplements," Kitchin said.
Furthermore, taking Zinc and Magnesium together may offer additional benefits. You can choose to take Zinc and Magnesium separately or a Calcium, Magnesium, and Zinc combination that helps support strong bones with Calcium, helps support a healthy heart with Magnesium, and supports a healthy immune system with Zinc.
Using cholecalciferol together with magnesium citrate can lead to elevated magnesium blood levels, particularly in individuals with reduced kidney function.
But if you do take magnesium, Erin Stokes, ND, recommends not taking it at the same time as your multivitamin, as it may interfere with the absorption of smaller minerals found in the multivitamin, like iron and zinc.
Thus, vitamin D at physiological doses may enhance magnesium absorption in non previously vitamin D-depleted pigs fed diets with abundant magnesium. This nutritional situation may help explain the predominant bone-resorbing effect of vitamin D supplementation.
Very low magnesium levels may cause:
Headaches. Nighttime leg cramps. Numbness or tingling in the legs or hands. General body weakness.
Magnesium deficiency can cause a wide variety of features including hypocalcaemia, hypokalaemia and cardiac and neurological manifestations. Chronic low magnesium state has been associated with a number of chronic diseases including diabetes, hypertension, coronary heart disease, and osteoporosis.
Stool softener: Magnesium draws water into the intestines, working as an osmotic laxative. This increase in water stimulates bowel motion, or motility. It also softens and increases the size of the stool. This prompts a bowel movement and helps to make stools easier to pass.
But three nutrients are especially useful for several reasons, which we intend to outline in this article. Namely, vitamin D, vitamin B12 and magnesium. And getting enough of them, in combination, couldn't be more timely.
Magnesium and calcium should not be taken at the same time, as both minerals together can impair absorption in the intestines. An optimal recommendation is to take calcium in the morning and magnesium in the evening. The reason for this is that both have a similar chemical structure.