It is believed that OCD likely is the result of a combination of neurobiological, genetic, behavioral, cognitive, and environmental factors that trigger the disorder in a specific individual at a particular point in time.
What causes OCD? Experts aren't sure of the exact cause of OCD. Genetics, brain abnormalities, and the environment are thought to play a role. It often starts in the teens or early adulthood.
Imaging, surgical, and lesion studies suggest that the prefrontal cortex (orbitofrontal and anterior cingulate cortexes), basal ganglia, and thalamus are involved in the pathogenesis of obsessive-compulsive disorder (OCD).
Many investigators have contributed to the hypothesis that OCD involves dysfunction in a neuronal loop running from the orbital frontal cortex to the cingulate gyrus, striatum (cuadate nucleus and putamen), globus pallidus, thalamus and back to the frontal cortex.
The bottom line for patients
"We know that OCD is a brain-based disorder, and we are gaining a better understanding of the potential brain mechanisms that underlie symptoms, and that cause patients to struggle to control their compulsive behaviors," says Norman.
Obsessive compulsive disorder, or OCD, is an anxiety disorder which, like many anxiety disorders, is marked by low levels of serotonin. Serotonin, a type of neurotransmitter, has a variety of functions that make a deficiency a serious and anxiety producing issue.
Brain scans may be helpful in showing the differences in the structure and function of brain regions in individuals with OCD. Such studies can provide new targets for the treatment of OCD.
The inheritance pattern of OCD is unclear. Overall, the risk of developing this condition is greater for first-degree relatives of affected individuals (such as siblings or children) as compared to the general public.
These infections may include: strep, influenza, mycoplasma pneumonia, Lyme disease, herpes virus, mononucleosis and Coxsackie virus. This autoimmune response targeting the basal ganglia can cause brain inflammation and the onset of neuropsychiatric symptoms, including OCD-like behaviors.
The onset of OCD is not limited to the original meaning of trauma; rather, traumatic experiences such as unexpected exposure to contaminants or various stressful life events often cause the onset of OCD.
Can OCD lead to brain damage? OCD fundamentally changes the brain, showing a significant reduction in grey matter density in some regions. In severe cases, this can permanently change how the brain works for patients with OCD. However, most people can lead normal and happy lives with therapy and medication.
What happens if OCD is left untreated? Left untreated, the recurring thoughts and urges of OCD can interfere with your thinking and decrease concentration and short-term memory. Intense compulsions can drain your physical and mental energy and consume valuable time.
Older patterns take more time to undo. It can be done though it feels overwhelming.” Essentially, OCD symptoms can worsen over the years when obsessive compulsions and obsessions are left unchecked. Ultimately, thoughts and behaviors worsen as they form a loop that repeats and repeats.
The bottom line
OCD can manifest in four main ways: contamination/washing, doubt/checking, ordering/arranging, and unacceptable/taboo thoughts. Obsessions and compulsions that revolve about contamination and germs are the most common type of OCD, but OCD can cover a wide range of topics.
Ongoing anxiety or stress, or being part of a stressful event like a car accident or starting a new job, could trigger OCD or make it worse. Pregnancy or giving birth can sometimes trigger perinatal OCD.
People with OCD experience recurrent and persistent thoughts, images or impulses that are intrusive and unwanted (obsessions). They also perform repetitive and ritualistic actions that are excessive, time-consuming and distressing (compulsions).
People struggling with Obsessive Compulsive Disorder (OCD) are often misdiagnosed as having other psychological conditions. One of the most common misdiagnoses for this population is Generalized Anxiety Disorder (GAD). This diagnostic problem arises for two reasons.
Although both OCD and ASD have similar symptoms, they are different conditions. OCD is a mental health disorder, whereas ASD is a developmental condition. ASD is a condition that a person is born with. OCD can develop during a person's lifetime.
Risk Factors
OCD is a common disorder that affects adults, adolescents, and children all over the world. Most people are diagnosed by about age 19, typically with an earlier age of onset in boys than in girls, but onset after age 35 does happen.
OCD is most commonly triggered in older teens or young adults. Studies indicate that late adolescence is a period of increased vulnerability for the development of OCD. Boys are more likely to experience the onset of OCD prior to puberty and those who have a family member with OCD or Tourette Syndrome are most at risk.
OCD obsessions are repeated, persistent and unwanted thoughts, urges or images that are intrusive and cause distress or anxiety. You might try to ignore them or get rid of them by performing a compulsive behavior or ritual. These obsessions typically intrude when you're trying to think of or do other things.
There is growing evidence that the major basis of OCD is in the brain and nervous system.
Unfortunately, OCD doesn't just go away. There is no “cure” for the condition. Thoughts are intrusive by nature, and it's not possible to eliminate them entirely. However, people with OCD can learn to acknowledge their obsessions and find relief without acting on their compulsions.