Advanced pyoderma gangrenosum Pyoderma gangrenosum can cause painful, open sores (ulcers) that have bluish, overhanging borders. Pyoderma gangrenosum (pie-o-DUR-muh gang-ruh-NO-sum) is a rare condition that causes large, painful sores (ulcers) to develop on your skin, most often on your legs.
Skin lesions are common and may be the result of an injury or damage to your skin, like sunburn. They're sometimes a sign of underlying conditions, like infections or autoimmune diseases. The majority of skin lesions are noncancerous and harmless (benign), but they can be a sign of something more serious.
Skin lesions are very common and often appear as a result of a localized damage to the skin, like sunburns or contact dermatitis. Others, however, can be manifestations of underlying disorders, such as infections, diabetes, and autoimmune or genetic disorders.
Dermatitis is inflammation of the upper layers of the skin, causing itching, blisters, redness, swelling, and often oozing, scabbing, and scaling. Known causes include dry skin, contact with a particular substance, certain drugs or medications, and varicose veins.
Symptoms of Impetigo
Starts as small red bumps. These change quickly to cloudy blisters or pimples. Then, they become open sores which drain fluid or pus. Any sore or wound that grows and doesn't heal is usually impetigo.
Slow-healing wounds, including leg and foot ulcers, are a known complication of several autoimmune inflammatory diseases, including rheumatoid arthritis (RA), lupus and scleroderma. For many people, these wounds can take months or even years to heal.
Conditions such as chronic venous insufficiency, arterial insufficiency, and pressure over time, can lead to the reduced reparation capacity of skin injuries, which can lead to non-healing ulcers. A non-healing ulcer, however, should not be regarded as a disease, but rather as a symptom of an underlying state.
Epidermolysis bullosa is a group of rare diseases that cause the skin to be fragile and to blister easily. Tears, sores, and blisters in the skin happen when something rubs or bumps the skin. They can appear anywhere on the body.
Main symptom of ecthyma is a small blister with a red border that may be filled with pus. The blister is similar to that seen with impetigo, but the infection spreads much deeper into the skin. After the blister goes away, a crusty ulcer appears.
Kaposi sarcoma – A type of cancer that develops in the cells that line lymphatic and blood vessels, Kaposi sarcoma can cause deep red, purple, or brown lesions to form on the skin's surface.
[3] Such lesions may pose a diagnostic challenge, as the clinical presentation and the possible causative microorganisms are extensive. [4] DNA viruses, including members of the Herpesviridae, Papillomaviridae, and Poxviridae families, are known to cause oral lesions.
The most common bacterial skin pathogens are Staphylococcus aureus and group A β-hemolytic streptococci. Herpes simplex is the most common viral skin disease. Of the dermatophytic fungi, Trichophyton rubrum is the most prevalent cause of skin and nail infections.
Autoimmune blistering skin diseases include: Pemphigus: A group of intraepidermal blistering disorders that cause erosions and/or sores on the skin, mouth, throat, nose, eyes, scalp, or genitals (includes pemphigus vulgaris and pemphigus foliaceous)
Stress rashes often appear as raised red bumps called hives. They can affect any part of the body, but often a stress rash is on the face, neck, chest or arms. Hives may range from tiny dots to large welts and may form in clusters. They may be itchy or cause a burning or tingling sensation.
Many fibro warriors experience skin issues such as rashes, redness, or easy bruising, though they may not always realize these symptoms are related to fibromyalgia until they talk to others who have experienced the same thing.
Shingles can occur anywhere on your body. It typically looks like a single stripe of blisters that wraps around the left side or the right side of your torso. Shingles is caused by the varicella-zoster virus — the same virus that causes chickenpox.
Leukemia-related skin rashes come from broken capillaries that leak blood into layers of the skin. Leukemia disrupts the production of platelets, a type of cell that plays a role in blood clotting. This means that when small vessels burst, blood leaks out and accumulates on different layers of the skin.
Staphylococcal scalded skin syndrome (SSSS) is a serious skin infection. The infection causes peeling skin over large parts of the body. It looks like the skin has been scalded or burned by hot liquid.
Melanoma – Nearly 80% of skin cancer-related deaths are caused by melanoma. People who develop melanoma often notice sores that don't heal, areas of darker pigmentation spreading out from a mole, or quickly growing or changing spots.
There can be many reasons a wound doesn't heal. Lifestyle factors, including a poor diet, not getting enough movement to offload the wound, smoking, and taking certain medications, can all contribute. Many times, a wound doesn't heal because of an infection or bacterial invasion.
Pemphigus is a rare group of autoimmune diseases that causes blisters on the skin and mucous membranes throughout the body. It can affect the mouth, nose, throat, eyes, and genitals.
Duke dermatologists diagnose autoimmune skin diseases like pemphigus, pemphigoid, scleroderma, morphea, dermatomyositis, dermatitis herpetiformis, vasculitis, lupus, and Sjögren's syndrome -- all of which occur when the body's immune system attacks healthy skin or tissue.
Some common autoimmune diseases, including Type 1 diabetes mellitus, are relatively easy to diagnose, while others, such as vasculitis, Addison's disease, lupus, and other rheumatic diseases, are more difficult.
Signs of sepsis are: • Pale, blotchy or blue skin, lips or tongue. Blotchy skin is when parts of your skin are a different colour than normal. Sometimes it is hard to know if you or somebody you look after has sepsis, or if it is something else, like flu or a chest infection.