Aspartame Withdrawal Symptoms: How Long Can You Expect Them to Last? It can take 14-30 days to get through the often debilitating symptoms of aspartame withdrawal.
Aspartame is digested in the small intestine and the hydrolyzed components are absorbed and metabolized following their normal metabolic pathways. Steviol glycoside is fermented by the gut microbiota to form steviol, which is absorbed into the liver and excreted in the urine.
Sugar is better for you than artificial sweeteners. Or even better yet — no added sugar. That's your absolute best bet. “Really, both sugar and artificial sweeteners are a problem for your health,” says functional medicine specialist Melissa Young, MD.
Artificial Sweeteners. The absolute worst sweeteners are artificial sweeteners, such as sucralose, saccharin, and aspartame. These are the worst sugar substitutes because these sweeteners are manufactured in a lab, meaning they're not found in nature.
The study demonstrated that two types of gut bacteria which are present in all gut microbiotas – E. coli and E. faecalis – had an increased ability to be pathogenic when exposed to sweeteners. These pathogenic bacteria were found to attach to, invade and kill gut epithelial cells that line the wall of the intestine.
Though widely available throughout the world, in 1991 stevia was banned in the U.S. due to early studies that suggested the sweetener may cause cancer.
The side effects of artificial sweeteners may include: digestive issues, increased blood sugar levels, a higher risk of cancer, increased blood pressure and adverse effects on those with pre-existing mood disorders. Artificial sweeteners may also have an effect on some people's immune systems.
While both Coca-Cola Zero and Diet Coke contain the same sweeteners (a blend of aspartame and acesulfame-potassium or Ace-K) and contain zero calories, Coca-Cola Zero uses a different flavour base and delivers the great taste of Coca-Cola with zero sugar.
Several studies in recent years have reported that low-calorie sweeteners in foods and beverages disrupt the human metabolism, promoting the development of diabetes and obesity. But other studies have found that consuming low-calorie drinks and food has little impact on metabolism and might actually aid in weight loss.
In 2022, the NutriNet-Santé cohort study reported that adults who consumed higher amounts of aspartame were slightly more likely to develop cancer overall (1.15 times the risk), breast cancer (1.22 times the risk), and obesity-related cancers (1.15 times the risk) than those who did not consume aspartame (4).
Some research on long-term, daily use of artificial sweeteners suggests a link to a higher risk of stroke, heart disease and death overall.
The side effects of artificial sweeteners include: headache, depression, increased risk of cancer, and weight gain due to increased appetite, as well as the two issues below (impact on gut health and increased diabetes risk).
Large-scale population studies have found that the consumption of artificial sweeteners, particularly in diet sodas, is associated with increased weight gain and abdominal fat over time.
Stevia is also widely sold in other East Asian countries and India. Stevia is approved for sale in the United States and Canada despite some resistance among nutritionists and medical researchers, but the European Union has for decades banned it owing to health concerns.
Stay on the safe side and avoid use. Allergy to ragweed and related plants: Stevia is in the Asteraceae/Compositae plant family. This family includes ragweed, chrysanthemums, marigolds, daisies, and many other plants. In theory, people who are sensitive to ragweed and related plants may also be sensitive to stevia.
The consumption of commonly used non-nutritive artificial sweeteners has driven the development of glucose intolerance by inducing changes in the composition and function of the intestinal microbiota. Intestinal microbial communities are unknown to play a significant and central role in human disease and health.
Research has shown that consuming artificial sugar may actually be harmful. Side effects of artificial sweeteners may include things like weight gain, poor blood sugar control, and an unhealthy gut. It is best to limit your use of artificial sweeteners when possible, just as with sugar.
Aspartame Aspartame (also known as Equal) is one of the most popular artificial sweeteners, adding sweetness to diet sodas, desserts, cereals, and many other foods and beverages.
Stevia — "safe"
Steviol glycosides, also known as stevia and its brand-name derivatives such as Stevia in the Raw and Sweetleaf, are natural low-calorie sweeteners.
Because coconut sugar is a plant-based, natural sweetener, some people feel it is more nutritious than regular table sugar. In reality, coconut sugar is almost identical to regular cane sugar in terms of nutrients and calories.