One clinical study found that people who took daily CoQ10 supplements within 3 days of a heart attack were less likely to have subsequent heart attacks and chest pain. They were also less likely to die of heart disease than those who did not take the supplements.
CoQ10 supplements appear to be safe and to produce few side effects when taken as directed. Mild side effects might include digestive problems such as: Upper abdominal pain. Loss of appetite.
While it's generally considered to be safe for healthy adults, CoQ10 can be potentially harmful to people with certain conditions or those taking certain medications. The typical dose ranges from 100 mg of CoQ10 or 25 mg of ubiquinol daily for generally healthy people not taking any medications.
While most people tolerate coenzyme Q10 well, it can cause some mild side effects including stomach upset, loss of appetite, nausea, vomiting, and diarrhea. It can cause allergic skin rashes in some people. It also might lower blood pressure, so check your blood pressure carefully if you have very low blood pressure.
Research indicates that up to 50% of overweight people have low serum CoQ10 levels, which can slow their metabolism. For our patients, daily supplementation of CoQ10 can lead to doubling their weight loss over several months with the same calorie intake.
Due to it's antioxidative effects, research has found that CoQ10 reduces inflammation in the body. This is significant because so many diseases are caused by inflammation. We are realizing that inflammation is often due to our poor health habits, insufficient sleep, and… you guessed it – lack of nutrients!
If you are taking CoQ10 vitamins every day, research shows that the body will show the effects as early as two weeks into daily supplementation. Some benefits may take longer than others, but plasma levels show an increase in CoQ10 levels early on, meaning CoQ10 is benefiting the body at a cellular level very quickly.
There are no apparent interactions between vitamin D and CoQ10, showing they're safe to supplement together. Some studies show that CoQ10 and vitamin D are beneficial for supporting heart health and exert protective effects on cardiovascular and renal health.
If you have been taking CoQ10 supplements while trying to conceive or through fertility treatments, we recommend stopping as soon as you are pregnant UNTIL you discuss it with your doctor. Up next: Ubiquinone vs. Ubiquinol: Which Type of CoQ10 is Better?
CoQ10 supplements can be taken without a duration limit. Clinical studies of high doses have lasted several years without issue. At the very least, you should take CoQ10 for a few weeks. It's not an acute kind of supplement that you take on an as-needed basis.
In addition to reducing the risk of cardiovascular problems in patients with liver disease, CoQ10 supplementation may also benefit the disease process within the liver by reducing inflammation and oxidative stress.
Preclinical and clinical studies have shown that CoQ10 has anti-inflammatory and antioxidant effects, and effects on mitochondrial dysfunction, which have been linked to the inflammatory response.
Answer: Yes. Although CoQ10 is generally well-tolerated, it can cause gastrointestinal symptoms such as nausea and diarrhea in a small percentage of people.
To oversimplify, CoQ10 improves the blood flow and prevents plaque build-up in the arteries.
CoQ10 is essential for heart health, but it also may have anti-aging benefits, boost immune function, and support normal brain function. Omega-3s are vital for cardiovascular health and proper brain function.
The data on CoQ10 and blood pressure is mixed, and most data suggests CoQ10 does not have an impact on heart rate [1,15]. Fish oil, however, has shown promising results in many research studies for lowering blood pressure and was shown to decrease heart rate in a few trials [10,16].
Answer: Yes, it is possible that CoQ10 is making it harder for you to fall asleep. Fortunately, there are ways to minimize this effect. Learn more in the Concerns and Cautions section of the CoQ10 and Ubiquinol Supplements Review.
- Q10 helps to reduce the emergence of fine lines & wrinkles
With all the energy coenzyme Q10 provides the skin and with it helping to support the production of collagen, it is a highly effective ingredient in creams that help to fight the signs of ageing skin - such as fine lines and wrinkles.
The human digestive system can only absorb so much CoQ10 at a time. One study found that 100 mg twice a day at separate times produced a better increase in serum levels than a single 200 mg dosing. But if you're likely to forget to take that second dose, you can take 200 mg at once.
Many cardiologists place their patients on CoQ10 to help cardiac function as well as to reduce the bad side effects of statin cholesterol drugs. The supplement also may help decrease the pain of rheumatoid arthritis by decreasing the bad inflammatory chemicals that lead to cartilage breakdown.
These results show that oral administration of coenzyme Q10 increases both brain and brain mitochondrial concentrations. They provide further evidence that coenzyme Q10 can exert neuroprotective effects that might be useful in the treatment of neurodegenerative diseases.
Speeding up metabolism with CoQ10 is a safe way to help weight loss. CoQ10 is also a good antioxidant and some evidence shows it may be helpful for those with macular degeneration and diabetes.