Lymphomas are caused by cancerous lymphocytes. Hodgkin lymphoma and NHL are two main types of lymphoma. While both cancers develop in your immune system, the primary difference in the lymphomas is the presence of a specific abnormal cell found in the biopsy.
The lesions, or tissue anomalies, of this disorder cause the lymph nodes to become enlarged (lymphadenopathy), inflamed and painful. The exact cause of Kikuchi's disease is not known. Perhaps the primary threat is a misdiagnosis of a malignant lymphoma.
Non-Hodgkin lymphoma is more common than Hodgkin lymphoma, and both types are slightly more common in men. Although both diseases can be diagnosed at any age, Hodgkin lymphoma is most common in young adults ages 15 to 40 and older adults over age 55. Non-Hodgkin lymphoma is typically diagnosed in adults over age 60.
Hodgkin's lymphoma is a type of cancer that affects the lymphatic system, which is part of the body's germ-fighting immune system. In Hodgkin's lymphoma, white blood cells called lymphocytes grow out of control, causing swollen lymph nodes and growths throughout the body.
Signs and Symptoms
The most common symptom of Hodgkin lymphoma is one or more enlarged (swollen) lymph nodes. The enlarged lymph node may be in the neck, upper chest, armpit, abdomen or groin. The swollen lymph node is usually painless.
Burkitt lymphoma: Considered the most aggressive form of lymphoma, this disease is one of the fastest growing of all cancers. Burkitt lymphoma, named for the surgeon who first identified the cancer in the 1950s, accounts for about 2 percent of all lymphoma diagnoses.
Survival data regarding Hodgkin vs. non-Hodgkin lymphoma depends on each patient's specific situation, but in general, the five-year relative survival rate for Hodgkin lymphoma is higher than that of non-Hodgkin lymphoma. One reason may be that non-Hodgkin lymphoma is often diagnosed when the cancer is more advanced.
Increased risk of NHL associated with personal histories of several ADs [such as rheumatoid arthritis (RA), Sjögren syndrome, hemolytic anemia, psoriasis, discoid/systemic lupus erythematosus (DLE/SLE), systemic sclerosis, polyarteritis nodosa, sarcoidosis, Crohn disease, Hashimoto/hypothyroidism, and celiac disease] ...
Benign etiologies of lymphadenopathy can include infections, autoimmune disorders, drug hypersensitivity reactions, sarcoidosis, and amyloidosis.
Kikuchi-Fujimoto disease (KFD), or histiocytic necrotizing lymphadenitis, is an extremely rare entity belonging to the large group of diseases that may cause lymph node enlargement.
Urgent referral to a specialist
night sweats. unexplained weight loss. itchy skin. shortness of breath or cough.
To diagnose non-Hodgkin lymphoma, NYU Langone doctors perform a biopsy, in which they take a tissue sample from a swollen lymph node found during the physical exam or with imaging tests, such as CT, PET, or MRI, which doctors often use when diagnosing cancer, and evaluate it under a microscope.
However, biopsies can lead to misdiagnosis, as acute EBV in lymphoid tissue can mimic both Hodgkin's and non-Hodgkin's lymphoma (NHL) resulting in inappropriate diagnosis and treatment [2,5]. EBV causes tumor formation by modifying B-cell growth transcription factors [6,7].
Around 80 out of 100 people (around 80%) will survive their Hodgkin lymphoma for 5 years or more after diagnosis.
Follicular lymphoma is usually not considered to be curable, instead categorized as more of a chronic disease. Patients can live for many years with this form of lymphoma.
The 5-year relative survival rate of people with localized Hodgkin lymphoma is 93%. If the cancer spreads regionally, the 5-year relative survival rate is 95%. If the cancer has spread to different parts of the body, the 5-year relative survival rate is 83%.
Blastic NK cell lymphoma
This very rare type of T cell lymphoma only affects a few people each year. It usually affects adults. Blastic NK cell lymphoma tends to grow very quickly and can be difficult to treat. It can start almost anywhere in the body.
Follicular lymphoma
almost 90 in 100 people (almost 90%) survive their cancer for 5 years or more after diagnosis.
Hodgkin lymphoma is one of the most curable forms of cancer. After treatment is complete, your care team will develop a survivorship plan that minimizes long-term side effects of treatment. Those risks include infertility, secondary cancers or toxicities to vital organs such as the heart and lungs.
Hodgkin lymphoma is caused by a change (mutation) in the DNA of a type of white blood cell called B lymphocytes, although the exact reason why this happens isn't known. The DNA gives the cells a basic set of instructions, such as when to grow and reproduce.
Some people have Hodgkin lymphoma in their bone marrow when they're diagnosed. If you have this, it can cause the following symptoms: shortness of breath and tiredness because of anaemia from a low red blood cell count. increased risk of infections because of a low white cell count.
These are your lymph nodes. You'll find them not only on your neck, but in your armpits and groin too. They're a part of your body's normal defense system, which protects you against invading viruses and bacteria. Hodgkin's lymphoma is a type of cancer that starts inside the lymph nodes.