Adult-onset Still disease is a rare inflammatory arthritis with fevers, rash, and joint pain. Sometimes people may have just one episode while in others the symptoms persist. It can affect any joint, but the most commonly involved are knees, wrists, and ankles.
The cause of AOSD is unknown (idiopathic). Researchers believe that the disorder might be caused by a combination of genetic factors and an abnormal or exaggerated response to infections or other environmental exposures. AOSD is not a hereditary disease and usually does not run in families.
Adult Still disease (ASD) is a rare illness that causes high fevers, rash, and joint pain. It may lead to long-term (chronic) arthritis. Adult Still disease is a severe version of juvenile idiopathic arthritis (JIA), which occurs in children. Adults can have the same condition, although it is much less common.
Adult-onset Still's disease typically affects adults under age 35. Fewer than 1 in 100,000 people get it each year. There is no cure, but you can control your symptoms with treatment.
The mean duration of adult Still's disease was 10 years. Approximately half of patients continued to require medication even 10 years after diagnosis. Patients had significantly higher levels of pain, physical disability, and psychological disability when compared with the controls.
Adult-onset Still's disease is an autoimmune condition. This means that the condition is caused by your body's immune system. The immune system protects us from infection and other threats to the body, but in AOSD it attacks your own body by mistake.
Steroids. Many people who have adult Still disease require treatment with steroids, such as prednisone. These powerful drugs reduce inflammation. They may lower the body's resistance to infections and increase the risk of developing osteoporosis and diabetes.
Adult onset Still disease, also known as systemic onset juvenile idiopathic arthritis, is a rare systemic inflammatory disorder characterized by inflammatory polyarthritis, daily fever, and a transient salmon-pink maculopapular rash.
Adult-onset Still's disease is also called adult Still's disease and Wissler-Fanconi syndrome. This form of arthritis has no known cause. Some 76% of people are diagnosed with this disease before the age of 35. It seems to affect men and women equally.
Systemic lupus erythematosus and Still's disease are chronic autoimmune disorders of unknown etiology. Symptomatology of these diseases may be similar causing diagnostic difficulties. Long-term observation and immunological studies are essential to identify the definite disorder.
Central nervous system is rarely affected by inflammatory process in Still's disease. Nevertheless in case of neurological deficits appearance and brain MRI abnormalities in patient with Still's disease underlying autoimmunological process should be considered.
Treatment. Doctors use several drugs to treat adult Still's disease. Over-the-counter or prescription nonsteroidal anti-inflammatory drugs (NSAIDs) help to reduce mild pain and inflammation. Corticosteroids, such as prednisone, are needed if the disease is severe or doesn't respond to prescription NSAIDs.
Major criteria:
Fever of at least 39°C lasting at least one week. Arthralgias or arthritis lasting two weeks or longer. A nonpruritic macular or maculopapular skin rash that is salmon-colored in appearance and usually found over the trunk or extremities during febrile episodes.
Stress is the main trigger for AOSD flares.
Red meat and processed meats, including bacon, hot dogs, lunch meats and cured meats. Refined grains, including white bread, white rice, pasta and breakfast cereals. Snack foods, including chips, cookies, crackers and pastries.
Grapefruit juice can, however, interact with some medicines that doctors use to treat arthritis. People who are undergoing treatment should check with a doctor before incorporating it into their diet.
In general, avoid soda since it can be full of sugar, aspartame and phosphoric acid. The latter can negatively affect your body's ability to absorb calcium. Water can get a bit boring, but there are other ways to stay healthy and hydrated.
Still's disease is a rare, systemic, autoinflammatory disorder, which is often difficult to diagnose. It can start in childhood or adulthood, and has a range of symptoms. Low awareness of Still's disease may lead to diagnosis of other conditions first and therefore a treatment not targeting the actual disease.
Some people believe that apple cider vinegar contains anti-inflammatory properties that would aid in the symptoms of arthritis, however, this has not been proven in humans. There is not enough evidence to show that apple cider vinegar is an effective treatment for any symptoms relating to arthritis.
Central nervous system is rarely affected by inflammatory process in Still's disease. Nevertheless in case of neurological deficits appearance and brain MRI abnormalities in patient with Still's disease underlying autoimmunological process should be considered.
Adult-onset Still's disease (AOSD) is a rare splenic disorder with an unknown cause. It is not uncommon for AOSD to involve other organs, such as the liver; the kidney; the bone marrow; and, less often, the lungs.