Buspirone, also known by the brand name BuSpar, is a newer anti-anxiety drug that acts as a mild tranquilizer. Buspirone relieves anxiety by increasing serotonin in the brain—as the SSRIs do—and decreasing dopamine. Compared to benzodiazepines, buspirone is slow acting—taking about two weeks to start working.
Sertraline (Zoloft) and venlafaxine (Effexor) are equally useful for treating panic disorder with or without agoraphobia. They are also overall the most well-tolerated medications for the treatment of panic disorder.
Antidepressants are the first-line medications in the treatment of anxiety disorders.
Antihistamines (such as hydroxyzine) and beta-blockers (such as propranolol) can help mild cases of anxiety as well as performance anxiety, a type of social anxiety disorder.
Buspirone. This anti-anxiety medication may treat short- or long-term anxiety symptoms. Buspirone (BuSpar) works much more slowly than benzodiazepines and may not treat all types of anxiety disorder, but it causes fewer side effects and has a lower risk of dependency.
The first-line alternatives to SSRIs in GAD are SNRIs, buspirone, hydroxyzine, pregabalin, and bupropion. Benzodiazepines are not recommended first-line agents for GAD due to their prominent side effect profile.
These antidepressants generally cause fewer bothersome side effects and are less likely to cause problems at higher therapeutic doses than other types of antidepressants. SSRIs include fluoxetine (Prozac), paroxetine (Paxil, Pexeva), sertraline (Zoloft), citalopram (Celexa) and escitalopram (Lexapro).
If you experience anxiety
If you have a form of anxiety or phobia, an antidepressant could help you feel calmer and more able to deal with other problems. It could also help you feel more able to benefit from other anxiety treatments, such as cognitive behavioural therapy (CBT).
SSRIs are usually the first choice medicine for depression because they generally have fewer side effects than most other types of antidepressant. As well as depression, SSRIs can be used to treat a number of other mental health conditions, including: generalised anxiety disorder (GAD)
Selective serotonin reuptake inhibitors (SSRIs) and serotonin norepinephrine reuptake inhibitors (SNRIs) SSRIs and SNRIs are often the first-line treatment for anxiety. Common SSRI brands are Celexa, Lexapro, Luvox, Paxil, and Zoloft.
MM-120. The FDA has approved a phase 2b study of an optimized form of LSD for the treatment of anxiety. The drug, called MM-120, is being developed by MindMed and is intended to treat generalized anxiety disorders and other mental conditions. MindMed is expected to begin clinical trials in 2022.
Psychotherapy is a great way to reprogram the brain so that you can live your life without your stress and anxiety taking over. One of the most successful forms of psychotherapy is cognitive-behavioral therapy or CBT.
SSRI's are anti-depressants and are currently the most popular anti-depression / anti-anxiety drugs as they have fewer side effects than MAOI's. SSRI's include drugs such as Prozac, Luvox and Aropax. SSRI's must be taken on a daily basis for at least a few weeks before they are effective.
All anxiety medications come with a long list of potential side effects. The side effects of anxiety medications, also called anxiolytics, include sleepiness, fatigue, and a slowing of mental functioning. Depending on their class, these medications may also be habit-forming or even addictive.
A second therapeutic candidate, LYT-310 (oral cannabidiol), is expected to enter the clinic in Q4 of 2023.
Hydroxyzine is used to help control anxiety and tension caused by nervous and emotional conditions. It can also be used to help control anxiety and produce sleep before surgery. This medicine is also used to relieve symptoms of allergic conditions (eg, chronic urticaria and atopic and contact dermatoses).
SSRIs, SNRIs, buspirone, beta-blockers, pregabalin, gabapentin, hydroxyzine, PanX and diphenhydramine are all options for anxiety that are alternatives to addictive benzodiazepines. Non-pharmacological, non-narcotic treatments for anxiety are always best to use, when possible.
First-line drugs are the selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors. Benzodiazepines are not recommended for routine use. Other treatment options include pregabalin, tricyclic antidepressants, buspirone, moclobemide, and others.
Anxiety that interferes with day-to-day functioning or affects work, school, or social life, may be a symptom of an anxiety disorder. This interruption in daily routine is often the point at which treatment interventions are needed.
1. Celexa. Overall, Celexa seems to be one of the best-tolerated SSRIs for many people. It tends to cause less weight gain and may have a lower risk of causing insomnia than some SSRIs.