Dupuytren's contracture (also called Dupuytren's disease, Morbus Dupuytren, Viking disease, palmar fibromatosis and Celtic hand) is a condition in which one or more fingers become permanently bent in a flexed position.
It is unknown exactly what causes Dupuytren's contracture, but there are certain factors that increase the risk, such as being male, being over 50 years of age, and being of Northern European descent.
Tradition has it that the disease originated with the Vikings, who spread it throughout Northern Europe and beyond as they traveled and intermarried. After being present for hundreds of years, DD was named in the 19th century after a famous French surgeon, who was not the first to describe it.
The cause of Dupuytren's contracture is unknown, but risk factors include advancing age, Scandinavian and Celtic ancestry, and certain conditions such as epilepsy, alcoholism and diabetes. Treatment options include injections of corticosteroids into the palm and surgery.
Your hand will be numbed (using local anaesthetic) or you may be put to sleep (using general anaesthetic). Cuts will be made along your palm and finger and the thick tissue causing the contracture will be removed. This is the most common surgery for Dupuytren's contracture.
Dupuytren contracture occurs most commonly after the age of 50. Sex. Men are much more likely to develop Dupuytren than are women. In men, symptoms may be worse and progress more quickly.
Vitamin D deficiency may stimulate fibroblasts in Dupuytren's disease via mitochondrial increased reactive oxygen species through upregulating transforming growth factor-β1.
Dupuytren's contracture: This form of arthritis causes the tissue beneath the hand to develop nodules in the fingers and palms. These lumps can cause the fingers to stick in place.
Dupuytren contracture is usually passed down through generations in families and is the most common inherited disorder of connective tissue. The inheritance pattern is often unclear. Some people who inherit gene changes associated with Dupuytren contracture never develop the condition.
However, Dupuytren's can be associated with conditions that cause contractures in other areas of the body, including the: Knuckle pads (Garrod knuckle pads) Soles of the feet (Ledderhose disease) Penis (Peyronie's disease)
An estimated ten million Americans (thirty million worldwide) have signs of Dupuytren disease. Dupuytren celebrities include politicians Ronald Reagan, Margaret Thatcher, Mitt Romney, actor Paul Newman, singer Frank Sinatra, comedians Bill Murray, Chelsea Handler, and many, many others – in all walks of life.
Massage therapy may delay the progression of contractures and decrease recurrence in post-operative patients. Massage therapy treatment for Dupuytren's disease should not be vigorous and stretching should be a gentle exploration of range of motion.
Dupuytren's disease (also known as Dupuytren's contracture) is a benign condition of the skin characterized by the overgrowth of myofibroblasts.
It sometimes was erroneously called "Viking disease," since it was often recorded among those of Nordic descent. In Norway, about 30% of men over 60 years old have the condition, while in the United States about 5% of people are affected at some point in time.
Dupuytren nodules have been discovered to contain dense T-cell infiltrates, suggesting it is a T cell-mediated autoimmune disorder.
Are Dupuytren contracture and trigger finger the same thing? The answer to that question is no. Upon first glance, these two things might seem very similar, but they are actually very different medical conditions. In fact, the only similarity is that they both affect finger flexion.
Inflammatory infiltration of palmar tissue from Dupuytren's contracture has been reported by several authors, who concluded that Dupuytren's contracture may be a chronic inflammatory disease.
Over time it can cause 1 or more fingers to curl (contract) or pull in toward the palm. You may not be able to use your hand for certain things. In many cases, both hands are affected. There is no cure, but treatment can improve symptoms.
Dupuytren's contracture does not develop unless you have one of the genes known to cause it. Conditions that can promote the disease in people with one of the genes include diabetes, smoking, use of some anti-epileptic medications, high alcohol intake, high cholesterol, and injury.
Abstract. Dupuytren's disease (DD) is a fibroproliferative disorder affecting the palmar fascia of the hand. Risk factors include diabetes mellitus (DM), whereas a high body mass index (BMI) is associated with a lower prevalence of DD.
Dupuytren's contracture is hereditary and typically develops in men over the age of 60 (5). However, rock climbers may develop Dupuytren's contracture in their early 20's due to repetitive stress to the palmar fascia (1).
There are no proven ways to prevent Dupuytren's disease or limit its progress. Hand therapy and rehabilitation using thermoplastic night splints and regular physiotherapy exercises may aid in the postoperative recovery period.
A Dupuytren's contracture typically progresses (gets worse) very slowly, over a period of years. Signs and symptoms of the condition may include: Nodules. You may develop one or more small lumps, or nodules, in the palm of your hand.