Schizophrenia causes psychosis and is associated with considerable disability and may affect all areas of life including personal, family, social, educational, and occupational functioning. Stigma, discrimination, and violation of human rights of people with schizophrenia are common.
Schizophrenia patients also have high rates of co-occurring disorders, like substance abuse and depression. These additional disorders can make the underlying schizophrenia more difficult to treat and it is possible schizophrenia may even be misdiagnosed due to the existence of the other disorders.
Though schizophrenia isn't as common as other major mental illnesses, it can be the most chronic and disabling. People with schizophrenia often have problems doing well in society, at work, at school, and in relationships. They might feel frightened and withdrawn, and could appear to have lost touch with reality.
The exact causes of schizophrenia are unknown. Research suggests a combination of physical, genetic, psychological and environmental factors can make a person more likely to develop the condition. Some people may be prone to schizophrenia, and a stressful or emotional life event might trigger a psychotic episode.
Schizophrenia treatment includes medication, therapy, social and family support, and the use of social services. Treatment must be ongoing, as this is a chronic illness without a cure. When schizophrenia is treated and managed over the long-term, most people can live normal, productive, and fulfilling lives.
The majority of people with schizophrenia get better over time, not worse. For every five people who develop schizophrenia: One will get better within five years of experiencing their first symptoms. Three will get better, but will still have times when their symptoms get worse.
Some people do recover “fully” from schizophrenia. Ten years after diagnosis: 50% of people with schizophrenia recover or improve to the point they can work and live on their own. 25% are better but need help from a strong support network to get by.
Schizophrenia has been described as the “worst disease” to afflict mankind. It causes psychosis, which is an abnormal state of mind marked by hyperarousal, overactivation of brain circuits, and emotional distress. An untreated episode of psychosis can result in structural brain damage due to neurotoxicity.
Schizophrenia is typically diagnosed in the late teens years to early thirties, and tends to emerge earlier in males (late adolescence – early twenties) than females (early twenties – early thirties). More subtle changes in cognition and social relationships may precede the actual diagnosis, often by years.
While any mental health disorder can pose significant health challenges, eating disorders are currently the most deadly category of mental health conditions. Any mental health disorder can present risk factors across the duration of a person's life.
Schizoaffective disorder and schizophrenia share some symptoms and treatments. The main difference is that schizoaffective disorder has a mood compenent, which can involve mania or depression. Some researchers believe schizoaffective disorder is a more severe variant of schizophrenia.
Individuals with Borderline Personality Disorder (BPDs) become overwhelmed and incapacitated by the intensity of their emotions, whether it is joy and elation or depression, anxiety, and rage. They are unable to manage these intense emotions.
Schizophrenia is a severe mental health condition that can involve delusions and paranoia. A person with paranoia may fear that other people are pursuing and intending to harm them. This can have a severe impact on their safety and overall well-being.
They may believe other people are reading their minds, controlling their thoughts, or plotting to harm them. They may sit for hours without moving or talking. These symptoms make holding a job, forming relationships, and other day-to-day functions especially difficult for people with schizophrenia.
Schizophrenia is a condition that affects all areas of life, and that appears to include intelligence. Overall, people who live with schizophrenia have lower IQ scores than those who don't experience the condition.
Managing schizophrenia is a lifelong process. It can't be cured. But symptoms can often be managed with medicine and therapy.
Studies show that certain brain chemicals that control thinking, behavior, and emotions are either too active or not active enough in people with schizophrenia. Doctors also believe the brain loses tissue over time.
Inflammation and oxidative stress. Neuroinflammation early in life followed by chronic overactivation has been hypothesized to contribute to the etiology of schizophrenia; it is possible that high levels of inflammation play a role in treatment resistance as well.
In the past, it was accepted that schizophrenia can worsen as people age. However, research in recent years suggests that although some symptoms may get worse with age, others will remain stable, and some symptoms may actually improve with age.
Psychotic symptoms, difficulty expressing emotions and making social connections, a tendency to be isolated, and other issues get in the way of meeting friends and establishing relationships. Finding love while living with schizophrenia, however, is far from impossible.
People with schizophrenia experience difficulties in remembering their past and envisioning their future. However, while alterations of event representation are well documented, little is known about how personal events are located and ordered in time.
Most people with schizophrenia make a recovery, although many will experience the occasional return of symptoms (relapses). Support and treatment can help you to manage your condition and the impact it has on your life.
But a new drug is bringing hope to the field. Xanomeline-trospium, or KarXT, has a novel way of diminishing dopamine transmission that's showing promise at reducing symptoms while also limiting side effects.