Dupuytren's disease is common in Norway and northern Europe but rare in individuals who are not of European descent. The aboriginal Sami of the northernmost parts of Scandinavia are ethnically distinct from most NorwegiansNorwegians (Norwegian: nordmenn) are a North Germanic ethnic group and nation native to Norway, where they form the vast majority of the population. They share a common culture and speak the Norwegian language.https://en.wikipedia.org › wiki › Norwegians
Dupuytren contracture occurs most commonly after the age of 50. Sex. Men are much more likely to develop Dupuytren than are women. In men, symptoms may be worse and progress more quickly.
In all analyses, no evidence was found for an excess of Norse ancestry in Dupuytren's disease. We conclude that there is no genetic evidence for a 'Viking origin of Dupuytren's disease'.
Dupuytren's contracture is believed to run in families (be hereditary). The exact cause is not known. It may be linked to cigarette smoking, alcoholism, diabetes, nutritional deficiencies, or medicines used to treat seizures.
Dupuytren disease is a genetic disorder that often is inherited in an autosomal dominant fashion, but is most frequently seen with a multifactorial etiology. It is associated with diabetes, seizure disorders, smoking, alcoholism, HIV, and vascular disease.
DD is relatively rare, occurring in 1% to 2% of the population. The disease is more common in men; the incidence in women is approximately 15% of those requiring surgical care but becomes higher in those who require nonsurgical treatment. There is a progressive rise in incidence with age.
Causes. Dupuytren's contracture tends to run in families, so it could be genetic. It is more common in people of Scandinavian or Northern European decent. This association may be why it is sometimes called Viking disease.
Through DNA testing, it is possible to effectively trace your potential inner Viking and discover whether it forms part of your genetic makeup or not. However, it's not 100% definitive. There's no exact Nordic or Viking gene that is passed down through the generations.
Surnames ending in -son or -sen are an obvious sign of Scandinavian ancestry – but other names such as 'Linklater', 'Flett', 'Scarth', 'Heddle', 'McIvor', 'MacAulay' and 'McLeod', 'Roger/s' and 'Rogerson' and 'Rendall' could also be a sign.
It has been claimed that striking success can be gained in the treatment of Dupu'tren's contracture of the palmar fascia by simple oral administration of vitamin E in high dosage. It has been said that, after such treatment, thickening of the fascia disappears anti contracture of the fingers is relieved.
Both alcohol and smoking are frequently mentioned as risk factors for Dupuytren's contracture. “The evidence for smoking is stronger than for drinking, and it makes sense because smoking, like diabetes, decreases blood supply to the hand,” Evans says.
Steroid injections may help slow progression of the condition but won't help straighten your finger if you already have a contracture. If your finger is already bent, your doctor may recommend Xiaflex, a mixture of enzymes that is injected into the affected area to break up the tough tissue.
Dupuytren's contracture: This form of arthritis causes the tissue beneath the hand to develop nodules in the fingers and palms. These lumps can cause the fingers to stick in place.
In terms of the immunological features of DD, evidence has persistently suggested the involvement of both T and B lymphocytes in DD etiology [7, 38]. As such, the disease has frequently been termed a “T-cell-mediated autoimmune disorder” [6].
Dupuytren's contracture mainly affects the ring and little fingers. You can have it in both hands at the same time. It tends to get slowly worse over many months or years.
There is general agreement that Dupuytren's contracture is a genetic disorder that occurs predominantly in white men of Northern European ancestry. It appears rarely in the purely black population.
Frequency. Dupuytren contracture occurs in about 5 percent of people in the United States. The condition is 3 to 10 times more common in people of European descent than in those of non-European descent.
XIAFLEX is a prescription medicine used to treat adults with Dupuytren's contracture when a “cord” can be felt.
Dupuytren often runs in families but can skip several generations. One-fourth of Dupuytren patients don't know anyone in their family with it.
Dupuytren's contracture (also called Dupuytren's disease, Morbus Dupuytren, Viking disease, palmar fibromatosis and Celtic hand) is a condition in which one or more fingers become progressively bent in a flexed position.
The genetic legacy of the Viking Age lives on today with six per cent of people of the UK population predicted to have Viking DNA in their genes compared to 10 per cent in Sweden. Professor Willeslev concluded: "The results change the perception of who a Viking actually was. The history books will need to be updated."
Dupuytren's contracture can be considered a complication of diabetes and of the local neurovascular changes since both are often associated. The contracture is usually not severe in diabetes, is nodular in form, and usually crushes the palmar surface of the long and ring fingers.
This condition usually progresses slowly over years or even decades. However, there's not enough research to determine the average span for the progression of Dupuytren's contracture. Most who develop it are men over age 50.
Soft-tissue manipulation and massage can be especially beneficial during the early stages of Dupuytren's contracture. Due to the fact that this is often a progressive condition, there's simply no reason to wait to see if “it gets better” before booking an appointment with a chiropractor to try to manage symptoms.