So if someone has a packet of 400 mg ibuprofen tablets, for instance, they should not take more than three tablets per day (24 hours). Different NSAIDs shouldn't be combined with each other. But an NSAID can be combined with acetaminophen if one medication alone isn't effective enough.
So that your child's pain is well controlled, it is OK to alternate giving paracetamol and ibuprofen, or even to give both at the same time. If you do this, it can be easy to accidentally give too much of either medicine.
Giving paracetamol with other painkillers
Ibuprofen is the only safe painkiller to give children alongside paracetamol. However, do not give paracetamol and ibuprofen at the same time. You need to give these medicines 1 at a time (unless your child's doctor or nurse gives you different instructions).
It's safe to take ibuprofen with paracetamol or codeine. But do not take ibuprofen with similar painkillers like aspirin or naproxen without talking to a pharmacist or doctor.
Paracetamol. You can only take 2 paracetamol (500mg) every 4 to 6 hours, and no more than 8 in 24 hours. You shouldn't take any more than this amount. Always follow the instructions on the packet.
It's safe to take paracetamol with other types of painkiller that do not contain paracetamol, such as ibuprofen, aspirin or codeine. Do not take paracetamol alongside other medicines that contain paracetamol. If you take 2 different medicines that contain paracetamol, there's a risk of overdose.
The most powerful pain relievers are opioids. They are very effective, but they can sometimes have serious side effects. There is also a risk of addiction. Because of the risks, you must use them only under a doctor's supervision.
Taking ibuprofen and codeine with other painkillers
It's safe to take combined ibuprofen and codeine with paracetamol. Do not take combined ibuprofen and codeine with ibuprofen, aspirin or naproxen.
If you take too much
Taking 1 or 2 extra tablets is unlikely to harm you. Do not take more than 8 tablets in 24 hours. Taking too much paracetamol can be dangerous and you may need treatment. Too much paracetamol can cause liver damage.
Opioids do provide relief by blocking pain. But as a result, your body reacts by increasing the number of receptors to try to get the pain signal through again. So when the drug wears off, you will experience more pain for about three days.
Acetaminophen is generally considered safer than other pain relievers. It doesn't cause side effects such as stomach pain and bleeding.
During an overdose, the drug overwhelms the parts of your brain that control your respiratory and circulatory functions. Neurological signals are suppressed, leading to slowed breathing and heart rate. Sometimes, people who overdose may experience abnormal heart rhythms; sometimes they will enter full cardiac arrest.
Intravenous acetylcysteine is the antidote to treat paracetamol overdose and is virtually 100% effective in preventing liver damage when given within 8 hours of the overdose.
Taking 1 or 2 extra tablets is unlikely to harm you. Do not take more than 8 tablets in 24 hours. Taking too much paracetamol can be dangerous and you may need treatment. Too much paracetamol can cause liver damage.
What is the strongest anti-inflammatory medication? Research shows diclofenac is the strongest and most effective non-steroidal anti-inflammatory medicine available.10 Diclofenec is sold under the prescription brand names Cambia, Cataflam, Zipsor, and Zorvolex.
What is the safest painkiller to use? Paracetamol tends to have fewer side-effects than other over-the-counter painkillers. Ibuprofen and aspirin can cause stomach problems. Paracetamol is often better for people with conditions that cause bleeding.
Acetaminophen (Tylenol and other brands) is usually effective for mild pain and is easy on the stomach.
Your prescribing doctor will decide on your usual dosage, but it is usually up to 1 tablet every 6 hours. Take Endone at about the same time every day.
5. Can I take painkillers on an empty stomach? Ibuprofen, aspirin and other NSAIDs (non-steroidal anti-inflammatory drugs) can irritate the stomach lining, so it is best to take them with food, or a glass of milk. Paracetamol doesn't irritate the stomach lining so it won't matter if you haven't eaten.
If you take more than the recommended amount (an overdose), it can harm the liver, and occasionally the kidneys. The medical team will assess you. Based on the information that you give them and the results of your blood tests, they will decide if you need treatment to reduce the chance of damage to your liver.