BPD has been linked to the amygdala and limbic systems of the brain, the centres that control emotion and, particularly, rage, fear and impulsive automatic reactions.
It's thought that many people with BPD have something wrong with the neurotransmitters in their brain, particularly serotonin. Neurotransmitters are "messenger chemicals" used by your brain to transmit signals between brain cells.
Using real-time brain imaging, a team of researchers have discovered that patients with Borderline Personality Disorder (BPD) are physically unable to regulate emotion. The findings, by Harold W.
Hippocampus and, to some degree, amygdala atrophy have been found consistently in patients with BPD. Studies revealed hippocampus volume reductions between 13% and 20% as well as amygdala volume reductions between 8% and 24%.
Objective: Borderline personality disorder is a disabling and dramatic psychiatric condition. To date, its pathophysiology remains unclear. Scientific evidence seems to have found underlying, nonfocal, central nervous system dysfunction in borderline personality disorder.
That's not true! Although it is not caused by a chemical imbalance in the brain, such as what happens during a depressive episode, BPD does have biological foundations. BPD develops partly from having a highly sensitive nervous system.
In particular, there is evidence that BPD is commonly misdiagnosed as Bipolar Disorder, Type 2. One study showed that 40% of people who met criteria for BPD but not for bipolar disorder were nevertheless misdiagnosed with Bipolar Type 2.
MRI studies have demonstrated that people with BPD have reduced volume in the frontal lobe, bilateral hippocampus, bilateral amygdala (a reduced volume that has not always been replicated in MRI studies), left orbitofrontal cortex, right anterior cingulate cortex, and right parietal cortex and increased putamen volume.
Borderline personality disorder is mainly treated using psychotherapy, but medication may be added. Your doctor also may recommend hospitalization if your safety is at risk. Treatment can help you learn skills to manage and cope with your condition.
Results. BPD patients displayed enhanced retrograde and anterograde amnesia in response to presentation of negative stimuli, while positive stimuli elicited no episodic memory-modulating effects.
Stressful or traumatic life events
Often having felt afraid, upset, unsupported or invalidated. Family difficulties or instability, such as living with a parent or carer who experienced an addiction. Sexual, physical or emotional abuse or neglect. Losing a parent.
The condition seems to be worse in young adulthood and may gradually get better with age. If you have borderline personality disorder, don't get discouraged. Many people with this disorder get better over time with treatment and can learn to live satisfying lives.
The results shown that patients with BPD have lower responses to serotonergic stimulation in areas of prefrontal cortex, a region associated with regulation of impulsive behaviour.
Borderline personality disorder is a mental illness that severely impacts a person's ability to regulate their emotions. This loss of emotional control can increase impulsivity, affect how a person feels about themselves, and negatively impact their relationships with others.
Many people with BPD feel emotions deeply and find working in a caring role fulfilling. If you are an empathetic person, consider jobs such as teaching, childcare, nursing and animal care.
Results: People with Borderline Personality Disorder have a reduced life expectancy of some 20 years, attributable largely to physical health maladies, notably cardiovascular. Risk factors include obesity, sedentary lifestyle, poor diet and smoking.
Antipsychotics are widely used in BPD, as they are believed to be effective in improving impulsivity, aggression, anxiety and psychotic symptoms [Nose et al. 2006; American Psychiatric Association, 2001].
While 2014 research indicates that people with borderline personality disorder often experience co-occurring psychiatric conditions, the exact rate of schizophrenia and BPD comorbidity specifically isn't clear just yet. A 2010 study found that 17.6% of people diagnosed with schizophrenia also met the criteria for BPD.
Research has shown that the prognosis for BPD is actually not as bad at once thought. Almost half of people who are diagnosed with BPD will not meet the criteria for a diagnosis just two years later. Ten years later, 88% of people who were once diagnosed with BPD no longer meet the criteria for a diagnosis.
Borderline personality disorder (BPD) is one of the most damaging mental illnesses. By itself, this severe mental illness accounts for up to 10 percent of patients in psychiatric care and 20 percent of those who have to be hospitalized.
Personality disorders are some of the most difficult disorders to treat in psychiatry. This is mainly because people with personality disorders don't think their behavior is problematic, so they don't often seek treatment.
As a symptom
Some people with borderline personality disorder (sometimes referred to as BPD) can be markedly impulsive, seductive, and extremely sexual. Sexual promiscuity, sexual obsessions, and hypersexuality are very common symptoms for both men and women with BPD.