A Swedish study, using a lupus cohort (N=5,175) assembled from hospital discharge data, established a relative risk of cancer in SLE, compared to the general population, of 1.25 (95% confidence interval [CI] 1.14, 1.37)(3).
The 16 cancer types linked to lupus include non-Hodgkin's lymphoma, Hodgkin's lymphoma, leukemia, multiple myeloma, cervix, vagina/vulva, renal, bladder, esophagus, gastric, hepatobiliary, lung, oropharynx, larynx, non-melanoma skin, and thyroid cancers.
With age, symptom activity with lupus often declines, but symptoms you already have may grow more severe. The accumulation of damage over years may result in the need for joint replacements or other treatments.
The percentage of remission in different studies varies between 63 and 74.8% of LLDAS according to Tani et al.
With close follow-up and treatment, 80-90% of people with lupus can expect to live a normal life span. It is true that medical science has not yet developed a method for curing lupus, and some people do die from the disease. However, for the majority of people living with the disease today, it will not be fatal.
For people with lupus, some treatments can increase the risk of developing potentially fatal infections. However, the majority of people with lupus can expect a normal or near-normal life expectancy. Research has shown that many people with a lupus diagnosis have been living with the disease for up to 40 years.
Kidneys About one half of people with lupus experience kidney involvement, and the kidney has become the most extensively studied organ affected by lupus.
Although lupus is not preventable, people with lupus can take steps to manage their disease and prevent or minimize lupus flares: It's important for people with lupus to take their medications as directed by their health care providers.
People with lupus are at increased risk of developing infections. The most common infections for people with lupus include those of the respiratory tract, skin and urinary system.> Medical treatment for infection may be longer for a person with lupus than for the general population.
Sunlight, stress, smoking, certain medicines, and viruses may trigger symptoms in people who are most likely to get lupus due to their genes. Hormones such as estrogen. Lupus is more common in women during their childbearing years when estrogen levels are highest. Problems with the immune system.
Currently, there is no cure for lupus. To manage the disease, people rely on medications and lifestyle changes, such as getting enough rest, avoiding the sun, and exercising. In the last two years, three new medications were approved to treat lupus, two for kidney lupus and one for non-kidney lupus.
Doctors may use chemotherapy drugs to treat lupus. These medications suppress overactive immune reactions, helping ease inflammation, limit organ damage, and improve quality of life.
The chemotherapy drug cyclophosphamide is an U.S. Food and Drug Administration approved treatment for patients with severe lupus nephritis.
Although chemotherapy drugs can be used to treat lupus and cancer, lupus is not cancer. For some patients whose kidneys or central nervous systems are affected by lupus, a type of drug called an immunosuppressive may be used.
Gender: Even though anyone can get lupus, it most often affects women. They're nine to ten times more likely than men to develop it. Age: Lupus can occur at any age, but most are diagnosed in their 20s and 30s. Race: Lupus is two to three times more common in African-American women than in Caucasian women.
Anyone can get lupus; however, women get the disease about nine times more often than men. Most often it happens in people between ages 15 and 45 years, but lupus can occur in childhood or later in life as well.
Lupus is a chronic disease with no cure.
This means that you can manage it with treatment, but it will not go away. Treatment can help improve your symptoms, prevent flares, and prevent other health problems often caused by lupus. Your treatment will depend on your symptoms and needs.
People with lupus should avoid certain supplements, including echinacea, spirulina, and vitamin E. These supplements may increase the immune system response and trigger lupus symptoms. It is also helpful to avoid excess sun exposure, salt, and alfalfa sprouts, which may also make symptoms worse.
In some people, lupus will flare, become inactive (quiescent), and go into remission—this course of the disease may or may not occur regularly throughout their life. In other people, lupus will remain in a chronic (long-lasting) state of activity. Some people will have fairly frequent flares of illness.
Lupus is not a hereditary condition.
Lupus can slow the digestive process, and this can cause a wide variety of GI issues. Digestive problems may be the direct result of an attack by the immune system or from medications to treat lupus. These digestive difficulties include nausea, vomiting, diarrhea, or constipation.
Lupus is an autoimmune disease link—a disorder in which the body's immune system attacks the body's own cells and organs. Kidney disease caused by lupus may get worse over time and lead to kidney failure. If your kidneys fail, you will need dialysis or a kidney transplant to maintain your health.