The Ordinary Argireline Solution 10% This under-$10 serum is the product that started the “Botox in a bottle” trend on TikTok. Packed full of peptides, with continual use it dramatically reduces fine lines, wrinkles, and crepey skin.
“The phrase 'Botox in a bottle' is a term popularized on TikTok for topical products with antiaging properties that aim to reduce the appearance of fine lines and wrinkles on the face,” Libby explains. Essentially, these promote wrinkle-reducing, plumping, and firming benefits to reveal smooth, radiant skin.
These studies have found that argireline-containing products can indeed reduce the appearance of fine lines and can also prevent the development of dynamic wrinkles. Botox in a bottle products that contain argireline have been found to be very safe as well and there are no significant side effects.
Botox-in-a-Bottle works by applying a few drops of Argireline Solution 10% to the skin twice daily, then layering it with Matrixyl 10% + HA High Strength Peptide Formulation. When used daily, the effects resemble the results of Botox treatment, hence the term “Topical Botox.”
Allergan recommends that unopened Botox vials be refrigerated between 2oC and 8oC for up to 36 months (if it's the 100U vial) and up to 24 months (if it's the 200U vial). However, the company also announced that the drug remains stable even after five days at room temperature.
BOTOX Cosmetic is supplied in single-dose 50 Units and 100 Units per vial. Prior to intramuscular injection, reconstitute each vacuum-dried vial of BOTOX Cosmetic with sterile, preservative-free 0.9% Sodium Chloride Injection USP (see Table 1).
Argireline (Arg0), a mimetic of Botox, has been found to be safer than Botox and effective in reducing wrinkles, with efficacies up to 48% upon 4 weeks of twice daily treatment. However, the skin permeation of Arg0 is poor, due to its large molecular weight and hydrophilicity.
Are there side effects? While not everyone has side effects with Argireline, if you have sensitive skin, you may experience stinging upon application as well as redness and dry, flaky skin at contact points. The manufacturers also advise against applying products that contain a peptide to sunburned or irritated skin.
Which is better, argireline or retinol? It depends on your skin concern and age. While retinol can improve pore function and fade discoloration from sun damage, argireline is a quick-absorbing compound that is gentler on the skin and works effectively on fine lines and wrinkles.
There is no evidence, according to science, that argireline causes skin to sag.
Can I use Argireline Solution over the whole face and neck? Yes, you may.
Argireline is the most sought-after wrinkle reducer on the market today. It helps reduce the appearance of lines and wrinkles around the eyes, mouth and forehead. Its powerful effects are made possible by a peptide called argireline that has been proven to lessen facial tension, relaxing and smoothing out skin.
"Hyaluronic acid as a sole ingredient is the best option for topical application to mimic the effects of botox or fillers.
Great for my fine lines! I've noticed a difference my skin texture and lines in about 2-3 weeks! It works! I noticed it working after a short time!
Argireline is a peptide that works by inhibiting the release of neurotransmitters in the neuromuscular junction, producing a botox-like effect. Therefore, it is used as a safe needle-free alternative to botox treatment.
Main Benefits: Prevents the muscle movement that leads to wrinkle formation. Argireline also promotes collagen production and optimizes the function of collagen, which both fight fine lines and improve moisture levels in the skin, says Shah.
Apply a few drops to the forehead and around the eyes in the morning and evening.
The main difference between the DAXI and Botox (Dysport, and Xeomin) is how long it lasts. “Instead of having your treatment last about three to four months, we've seen that DAXI lasts a lot longer at about six to eight months,” Dr. Katz says.
Daxxify is different from Botox in that it works faster and for longer—most people will notice a major decrease in movement in two days with Daxxify, versus the usual 5-7 days with Botox, and Daxxify wears off after six months (on average), in comparison to Botox's three to four months.
Treating forehead lines, crow's feet, and frown lines are officially the most common and popular uses for cosmetic Botox.
Botox is measured in “units.” There are 100 units in one syringe of Botox. One area of the face can require as little as five units while other areas may need around 40 or more units.