Background: Adenosine receptor activation is essential for mediating the IS-limiting effects of statins. Caffeine is a nonspecific adenosine receptor blocker, and thus drinking CC may block the myocardial protective effects of statins.
A magnesium- and aluminum-containing antacid was reported to interfere with atorvastatin absorption. People can avoid this interaction by taking atorvastatin two hours before or after any aluminum/magnesium-containing antacids. Some magnesium supplements such as magnesium hydroxide are also antacids.
Although taking the two together has no direct risks, both statins and alcohol can impair liver function and cause tissue damage. Mixing alcohol and statins can, therefore, increase the burden on the liver, potentially raising the risk of liver damage or disease.
It's possible, although unlikely, that one particular statin may cause side effects for you while another statin won't. It's thought that simvastatin (Zocor) may be more likely to cause muscle pain as a side effect than other statins when it's taken at high doses.
If you've made lifestyle changes through diet and exercise that have lowered your cholesterol levels, you may not need to continue taking a statin. These changes can help reduce your risk of heart attack, stroke, or blocked arteries while allowing you to take one less medication.
Statin use is associated with increased calorie intake and consequent weight gain. It is speculated that statin‐dependent improvements in lipid profile may undermine the perceived need to follow lipid‐lowering and other dietary recommendations leading consequently to increased calorie intake.
Red wine can be the alcohol of choice as it possesses antioxidant properties. Studies reveal that moderate consumption of red wines can not only lower cholesterol levels but help prevent certain heart diseases.
Fear of side effects and perceived side effects are the most common reasons for declining or discontinuing statin therapy. Willingness to take a statin is high, among both patients who have declined statin therapy and those who have never been offered one.
Vitamin D supplement may have moderate or no effect on the dosage requirement or side effects of pravastatin, rosuvastatin and pitavastatin. Since vitamin D has mild HMG-CoA reductase activity, it will work synergistically with all statins.
Simvastatin, pravastatin & fluvastatin are statin's that work better if taken in the evening. Studies show that when simvastatin is taken at night, there is a greater reduction in LDL cholesterol than when the statin is taken in the morning.
CoQ10 Supplements
Coenzyme Q10 (CoQ10), a nutrient produced by the body and used for cellular energy, is often touted as being vital if you're taking statin drugs to lower cholesterol.
Accumulating databases from the US Food and Drug Administration Adverse Event Reporting System (FAERS) suggest that statin use is associated with an increased risk of sleep disturbances including insomnia [8]. In other studies hallucinations and nightmares during statin therapy were also observed [6, 7].
Cautions and interactions. Statins shouldn't be taken if you have severe liver disease or blood tests suggest that your liver may not be working properly. This is because statins can affect your liver, and this is more likely to cause serious problems if you already have a severely damaged liver.
The fiber and potassium in bananas can reduce the level of cholesterol and blood pressure. Banana is especially known as a good source of soluble fibre which will gives one a healthy body and good immune system.
The bad cholesterol is called LDL and the good cholesterol is called HDL. When people have high cholesterol their LDL (bad) is high and their HDL (good) is low. Eating healthy, regular exercise and drinking plenty of water will help to bring down cholesterol levels within 2-3 weeks.
Chicken eggs are an affordable source of protein and other nutrients. They're also naturally high in cholesterol. But the cholesterol in eggs doesn't seem to raise cholesterol levels the way some other foods, such as those high in trans fats and saturated fats, do.
The side effects of statins include diarrhoea and constipation, although no pathophysiological explanation is provided by the manufacturer. There are various mechanisms that have been postulated by which statins are thought to induce myotoxicity.
Joseph A. Hill, M.D., Ph. D. The controversy in the United Kingdom started in 2013 when the British Medical Journal (BMJ) claimed statins were being overprescribed to people with low risk of heart disease, and that the drugs' side effects were worse than previously thought.
Getting the right amount of sleep, about 7 1/2 hours, seems to prevent this. Plus getting the right amount of sleep will always give you more energy. Cat naps are good for you too. A recent study linked artery health to when you sleep.
The American College of Cardiology and American Heart Association developed some prescription guidelines. Typically, if a person's LDL cholesterol (bad cholesterol) is 190 or higher, they're often advised to start a statin.
If you forget to take your dose, take it as soon as you remember. If you do not remember until the next day, skip the missed dose and take the next one at the usual time. If you often forget doses, it may help to set an alarm to remind you.
Overall, statins are safe as a class of drugs. Serious adverse events are very rare. Among the individual medications, studies have shown that simvastatin (Zocor®) and pravastatin (Pravachol®) seem to be safer and better tolerated than the other statins.