Vitamin B6, also known as pyridoxine, has special importance as a precursor of serotonin and tryptophan and can also play a role in behavior and mood.
Serotonin does not occur in the foods we eat, however it is synthesized from tryptophan, an amino acid. Tryptophan is mostly found in high protein foods, like meat, fish and poultry.
B12 acts as a cofactor in synthesis of neurotransmitters such as serotonin and dopamine, thus B12 deficiency affects mood, emotions and sleeping and can lead to psychiatric disorders.
Research suggests that supplementing with magnesium may help to increase serotonin levels. In fact, low serotonin levels have been observed in patients with a magnesium deficiency. The study that discussed raising serotonin with magnesium reported success.
Increasing serotonin levels can be done naturally. The best ways to do this are eating well, getting out in the sun or supplementing with vitamin D, exercising, taking adaptogens, and managing stress. Serotonin can also be increased synthetically with antidepressants.
Vitamin B-3 and Vitamin B-9 can help people with depression because B vitamins help the brain manage moods. Vitamin D, melatonin and St. John's Wort are recommended for seasonal depression. Omega-3 fatty acids, magnesium and vitamin C may also help with depression.
5-HTP dietary supplements help raise serotonin levels in the brain. Since serotonin helps regulate mood and behavior, 5-HTP may have a positive effect on sleep, mood, anxiety, appetite, and pain sensation. 5-HTP is not found in the foods we eat, although tryptophan is found in foods.
Vitamins C, B6 and biotin help the normal energy production and the functioning of the nervous system. They are essential for creating critical molecules, such as serotonin that gives you positive feelings and is known as a happiness hormone. Serotonin needs vitamin B6 to synthesize.
Prolonged periods of stress can deplete serotonin levels. Our fast-paced, fast food society greatly contributes to these imbalances. Genetic factors, faulty metabolism, and digestive issues can impair the absorption and breakdown of our food which reduces our ability to build serotonin.
Vitamin D helps encourage serotonin production and release. If you're not getting enough vitamin D, taking a supplement may help reduce symptoms related to low serotonin levels, but check with your doctor before beginning supplementation.
Studies show that certain dietary supplements, including omega-3s, vitamin D, rhodiola, B12, and saffron, may be helpful for reducing depressive symptoms in some people.
Serotonin helps regulate the body's internal clock, including the ability to feel sleepy, remain asleep, enter rapid eye movement (REM) sleep, and wake in the morning. People with chronic insomnia, unusual sleep patterns, chronic fatigue, or consistently vivid dreams may have serotonin deficiency.
It's also possible to increase serotonin levels without taking medicine. One natural way to increase serotonin is by working out. When you pedal your bicycle or lift weights, your body releases more tryptophan, the amino acid your brain uses to make serotonin.
It turns out one study shows the supplement can be as effective as SSRIs in treating mild to moderate depression. The FDA hasn't yet rated magnesium as an effective treatment for depression; they need to see more studies before they'll take that step.
Magnesium was found usually effective for treatment of depression in general use.
Beyond its strength as an antioxidant, kiwi is also a fruit high in serotonin. A hormone that also functions as a neurotransmitter, serotonin is involved in a broad range of physiologic processes: it has digestive and cardiovascular functions, assists in learning and memory, and helps to regulate appetite and mood.
Avocado. If you are not a fan of walnuts, avocados are another excellent source of tryptophan, a key ingredient in serotonin synthesis. Avocados also have a myriad of other health benefits.
The highest concentration of serotonin was found in walnut (155 ± 57.0 µg/g). Raw (13.6 ± 2.14 µg/g) and roasted pecan (15.3 ± 1.27 µg/g), which belongs to the Juglandaceae family like walnut, were also found to contain higher serotonin concentrations compared to the other nuts.