There are many subsets of arthritis, but the arthritis seen in lupus closely resembles rheumatoid arthritis in that it is symmetric (affects the same locations on either side of the body) and usually affects the small joints of the hands, wrists, and feet.
During the course of their disease, approximately 95% of lupus patients will have joint symptoms − either arthritis or arthralgias. Arthritis in lupus is due to inflammation of the lining of the joint (called synovitis) that leads to swelling, tenderness, and stiffness. Arthralgia refers to joint pain without swelling.
Joint pain is common in lupus, especially in the small joints of the hands and feet. The pain often moves from joint to joint. Joint pain, swelling and stiffness can be the main symptoms for some people with lupus. In most cases, lupus is unlikely to cause permanent damage or change the shape of joints.
Lupus can also cause inflammation in the joints, which doctors call “inflammatory arthritis.” It can make your joints hurt and feel stiff, tender, warm, and swollen. Lupus arthritis most often affects joints that are farther from the middle of your body, like your fingers, wrists, elbows, knees, ankles, and toes.
You may experience pain and stiffness, with or without swelling. This affects most people with lupus. Common areas for muscle pain and swelling include the neck, thighs, shoulders, and upper arms.
Kidneys About one half of people with lupus experience kidney involvement, and the kidney has become the most extensively studied organ affected by lupus. Lungs About 50% of people with SLE will experience lung involvement during the course of their disease.
The ESR test can gauge how much inflammation is in your body by measuring how quickly red blood cells (erythrocytes) separate from other cells in the blood and collect as sediment (sed) in the bottom of a test. A high sed rate could indicate lupus or another inflammatory disease. C-Reactive Protein (CRP).
So, is RA Worse Than Lupus? Neither RA nor lupus is "worse" than the other. They are different conditions and require treatment accordingly. Lupus and RA patients can have a mild or severe form of either disease.
Lupus is not a form of arthritis, but it does include arthritis as one of the most common symptoms, so it is easy to see why some people think about it that way. It is very important not to make this mistake, because lupus is quite different than any other illness that causes arthritis.
Often you may wake up stiff, and that stiffness will gradually ease up as the day passes. But you may also find pain throughout the day in many joints (usually fingers, wrists, elbows, knees, ankles, and toes) on both sides of your body.
X-rays and/or other diagnostic imaging procedures: Osteoarthritis will often show up on an X-ray, while someone with lupus arthritis will commonly have normal X-rays, since lupus doesn't tend to cause bone erosion.
How long does a lupus flare last? Lupus flares can vary in length. Some may last several days; others may span weeks or more.
Blood and urine tests.
The antinuclear antibody (ANA) test can show if your immune system is more likely to make the autoantibodies of lupus.
About 95% of lupus patients will experience arthritis or arthralgias (joint pains) at some point during the course of their disease.
Lupus often causes skin rashes, arthritis, mouth sores, sun sensitivity, hair loss, or kidney problems, but these symptoms don't show up in MS. Even when lupus affects your nervous system, its most common symptoms are migraine, personality changes, seizures, or stroke, but these aren't typical for MS.
Antibody blood tests
The test you will hear about most is called the antinuclear antibodies test (the ANA test). 97% of people with lupus will test positive for ANA. ANA connect or bind to the nucleus or command center of the cell.
An examination of a sample of your urine may show an increased protein level or red blood cells in the urine, which may occur if lupus has affected your kidneys. Antinuclear antibody (ANA) test. A positive test for the presence of these antibodies — produced by your immune system — indicates a stimulated immune system.
Many people with lupus take NSAIDs to manage joint pain and swelling. Some NSAIDs (such as aspirin, naproxen and ibuprofen) are available over-the-counter and others require a prescription. Corticosteroids. Corticosteroids are powerful anti-inflammatory drugs.
Common triggers include:
Being out in the sun or having close exposure to fluorescent or halogen light. Infection. Injury. Stopping your lupus medicines.
Lupus and the intestines
Lupus can rarely cause vasculitis (inflammation of the blood vessels) in the intestines, sometimes called lupus enteritis. Symptoms include: Abdominal pain (pain in the belly area) Feeling very full or bloated.