SSRIs are usually the first choice medicine for depression because they generally have fewer side effects than most other types of antidepressant. As well as depression, SSRIs can be used to treat a number of other mental health conditions, including: generalised anxiety disorder (GAD)
Buspirone. This anti-anxiety medication may treat short- or long-term anxiety symptoms. Buspirone (BuSpar) works much more slowly than benzodiazepines and may not treat all types of anxiety disorder, but it causes fewer side effects and has a lower risk of dependency.
Sertraline (Zoloft) and venlafaxine (Effexor) are equally useful for treating panic disorder with or without agoraphobia. They are also overall the most well-tolerated medications for the treatment of panic disorder. Of the two, sertraline would be a safer choice for people with a history of heart problems.
SSRIs and SNRIs are often the first-line treatment for anxiety. Common SSRI brands are Celexa, Lexapro, Luvox, Paxil, and Zoloft. Common SNRI brands are Pristiq, Cymbalta, and Effexor XR. Pros: They are effective for a lot of people and they have a solid safety profile.
SSRIs are the most commonly prescribed class of antidepressants. This is because they're effective and well-tolerated antidepressants with little side effects. With many SSRIs available as generic products, this medication class typically costs less. SNRIs and bupropion are also common choices for similar reasons.
SSRIs are usually the first choice medicine for depression because they generally have fewer side effects than most other types of antidepressant.
Selective serotonin reuptake inhibitors (SSRIs).
Health care providers often start by prescribing an SSRI . These antidepressants generally cause fewer bothersome side effects and are less likely to cause problems at higher therapeutic doses than other types of antidepressants.
Benzodiazepines (also known as tranquilizers) are the most widely prescribed type of medication for anxiety. Drugs such as Xanax (alprazolam), Klonopin (clonazepam), Valium (diazepam), and Ativan (lorazepam) work quickly, typically bringing relief within 30 minutes to an hour.
People with a history of addiction may benefit from taking anxiety medications that don't have addictive properties. SSRIs, SNRIs, buspirone, beta-blockers, pregabalin, gabapentin, hydroxyzine, PanX and diphenhydramine are all options for anxiety that are alternatives to addictive benzodiazepines.
First-line drugs are the selective serotonin reuptake inhibitors and serotonin-norepinephrine reuptake inhibitors. Benzodiazepines are not recommended for routine use. Other treatment options include pregabalin, tricyclic antidepressants, buspirone, moclobemide, and others.
Selective serotonin reuptake inhibitors (SSRIs) are the most commonly prescribed antidepressants. They can ease symptoms of moderate to severe depression, are relatively safe and typically cause fewer side effects than other types of antidepressants do.
Selective serotonin reuptake inhibitors (SSRIs) are the drug that doctors most commonly prescribe to treat depression and anxiety disorders.
Examples of SSRIs that are commonly used to treat chronic anxiety include citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac), paroxetine (Paxil), and sertraline (Zoloft).
While some anxiety drugs can cause some rare but severe side effects, they are generally well tolerated with few mild symptoms.
Buspar® (Buspirone)
This non-addictive anxiety medication is similar to an SSRI in that it increases chemical messengers involving serotonin. Buspar only targets one subtype of the serotonin receptor, so it affects just one specific area of your brain.
Cognitive behavioral therapy (CBT) is the most effective form of psychotherapy for anxiety disorders. Generally a short-term treatment, CBT focuses on teaching you specific skills to improve your symptoms and gradually return to the activities you've avoided because of anxiety.
A second therapeutic candidate, LYT-310 (oral cannabidiol), is expected to enter the clinic in Q4 of 2023. A second therapeutic candidate, LYT-310 (oral cannabidiol), is expected to enter the clinic in Q4 of 2023.
Escitalopram (Lexapro) is a first-choice antidepressant for the treatment of depression and anxiety. Typically, you take it by mouth once daily. Escitalopram (Lexapro) is available as both a tablet and a liquid. Some people notice an improvement in their condition as early as a week after they start treatment.
Overall, citalopram appears to be the best-tolerated SSRI, followed by fluoxetine, sertraline, paroxetine, and fluvoxamine. The latter 2 drugs are associated with the most side effects and the highest discontinuation rates because of side effects in clinical trials.
Escitalopram and sertraline stand out.
Bupropion, citalopram, escitalopram, and sertraline were better tolerated than the other antidepressants. Escitalopram and sertraline were found to have the best combination of efficacy and acceptability.
Specifically, weight gain seems to be a common long-term risk, especially the medications that affect serotonin levels. This could be because serotonin is associated with an increase in appetite. There is also a risk of higher blood sugar levels and diabetes with taking antidepressants long-term.
Antidepressants are the first-line medications in the treatment of anxiety disorders. Anxiolytics may be used for a brief duration, but only if needed while an antidepressant is being initiated and titrated up.