In the MCU, fans have already seen Captain America and Vision lift Mjolnir, and while Jane is the first person to show her worthiness, there have been several in the comics.
Here's why Thor looked so worried when Captain America tried to lift Mjölnir in Avengers: Age of Ultron, as well as how the introduction of Mighty Thor in Thor: Love and Thunder is the MCU Phase 4's perfect callback to this iconic scene.
Red was part of a film crew that was transported to Asgard by Loki. And at Loki's behest, Red took Thor's Belt of Strength and bathed in the Fires of Geirrodur before claiming Thor's Iron Gloves. The gloves were the key, since they allowed Red to lift and wield Mjolnir without being worthy.
Yes, as a shock to many, Superman has briefly lifted the mighty hammer in a phenomenal crossover with Marvel and DC Comics.
Venom (2020)
During this battle, Venom (Eddie Brock) was given the powers of Captain Universe, and was able to wield the hammer. However, Venom took this advantage a step further by merging Mjolnir with the Silver Surfer's surfboard to create an even greater weapon.
Thanos didn't lift Mjolnir, Captain America did
With Mjolnir's worthiness enchantment resulted in Thor being able to lift the hammer only if he is considered to be worthy, but likewise, the enchantment is not discriminatory in nature, and anyone who is deemed worthy is able to lift the hammer.
Captain Marvel, aka Shazam, is one of the most powerful heroes DC has to offer. He's on Superman's level, though Shazam's powers are derived from magic. However, being powerful is not what makes Shazam worthy of Mjolnir. In fact, Shazam is not the one who is worthy of the hammer; Billy Batson is.
Yes, even Spider-Man has been worthy of holding the hammer of Thor. This is not your father's Spider-Man (well, actually, it could be if your dad was a kid in 1993), but instead is the Spider-Man of Marvel's distant future of 2099!
Is Spider-Man worthy enough to lift Mjolnir. The short answer is yes, Spider-Man is able to lift Mjolnir but it's not that simple. While Spider-Man can lift Mjolnir, Peter Parker cannot. That's because it's Miguel O'Hara's Spider-Man 2099 that can lift Mjolnir as he does in 1998's 2099: Manifest Destiny one-shot.
And not only that, their mission is noble enough that it's earned the loyalty of Mjolnir. While it is still Thor's hammer, it won't hurt one of the Panther Kings. It's even revealed that in the past, the first Black Panther actually once wielded the hammer himself, using it in unseen battle to protect the world.
In Marvel vs DC #2, the superheroes of both comic studios clashed against each other, and Wonder Woman proved herself worthy enough to wield Thor's mighty Mjolnir. While the God of Thunder accidentally drops his hammer while fighting Shazam, Wonder Woman picks it up to combine Amazonian and Asgardian strength.
Loki and Thor are both gods and have immense godly powers that make them somewhat impervious to harm, though they can be beaten; they can lose eyes (Thor) and they can die (Loki). If the metric is physical strength, then Thor is easily the winner.
In the comics, the Hulk has been depicted as being strong enough to lift Mjolnir, Thor's hammer, on multiple occasions.
Other than Thor and Odin, certain other individuals have proven worthy of lifting Mjolnir in the primary continuity: Roger "Red" Norvell (a deliberate ruse by Odin) Beta Ray Bill. Buri (also known as Tiwaz, Thor's great-grandfather)
But then, in 1991, Marvel released a "Thor's Hammer" trading card that claims that Mjolnir weighs precisely 42.3 pounds.
Based on the analysis of powers, speed, strength, durability, and combat, we can safely say that Odin is stronger than Thanos and outmatches him in almost every aspect. Thanos might be among the most feared villains in the Marvel Universe, but he comes nowhere near when compared to All-Father Odin.
Amid the chaos, which was worsened by the sudden appearance of the world serpent Jormungand, Natasha retrieved Mjolnir and was deemed worthy, becoming a super-spy thunder goddess hybrid, with a hammer for smashing and her widows bites for stinging.
Armed with the hammer Mjolnir, Thor is one of the strongest beings anywhere and he can fire powerful blasts of lightning. Alive for millennia, Thor has been fighting evil for a very long time and there are few who can match his skill. This is one of those fights where Venom just can't hurt Thor.
Hence, Mjolnir determines worthiness based on Odin's definition of worthiness. However, since Mjolnir also has a conscious being within it, in the form of God Tempest, another likely explanation is that it is God Tempest that determines the worthiness.
Thor was the only one able to lift the Mjolnir for the longest time, but things are different with Stormbreaker because everyone can use it - why? The MCU made a big deal about how Thor (Chris Hemsworth) was the only one worthy of lifting Mjolnir, but things are a bit different with his newer weapon, Stormbreaker.
Both in the comics and the MCU films, many characters other than Thor himself, both heroes and villains, have been able to lift Mjolnir. Only a select few, however, have been able to do so out of worthiness. From Throg to Beta Ray Bill, these heroes have proved that they have a heart as pure as the God of Thunder's.
Eitri reveals a plan to create Stormbreaker, an axe with powers similar to Mjolnir and the ability to summon the Bifröst. After Thor is nearly killed by helping Eitri restart the damaged forge to create the weapon, Groot completes Stormbreaker by using his own arm to bind the pieces together and create a handle.