More Serious Effects B12 injections may contribute to low potassium levels in your body. Though rare, this reaction can cause muscle cramping, extreme fatigue, and an irregular heartbeat.
Older adults and people with digestive tract conditions that affect absorption of nutrients also are susceptible to vitamin B-12 deficiency. Left untreated, a vitamin B-12 deficiency can lead to anemia, fatigue, muscle weakness, intestinal problems, nerve damage and mood disturbances.
Vitamin B12
As a general rule of thumb, take your B vitamins in the morning or with a meal. Vitamin B12, for example, should definitely be taken in the morning. This is because it is important for energy metabolism, which may interrupt your sleep if taken at night.
Vitamin B12 helps increase the body's production of melatonin, making it important for regulating sleep-wake cycles.
If you are low in B12, you will feel weak and tired. Vitamin B12 can give you more energy, boost your metabolism, and help you lose weight.
What is vitamin B12 and what does it do? Vitamin B12 is a nutrient that helps keep your body's blood and nerve cells healthy and helps make DNA, the genetic material in all of your cells. Vitamin B12 also helps prevent megaloblastic anemia, a blood condition that makes people tired and weak.
It may take a few weeks before your vitamin B12 levels and symptoms (such as extreme tiredness or lack of energy) start to improve. If you have hydroxocobalamin injections to boost your vitamin B12 levels at the start of treatment, the cyanocobalamin tablets may start to work within a few days.
Too much nicotinic acid can also cause low blood pressure, fatigue, headaches, rashes, and liver damage. Excess nicotinamide. High doses of nicotinamide, another form of vitamin B3, can cause diarrhea and increased bleeding. This can occur in doses of 500 mg per day.
Vitamin B12 works on the pineal gland, which is responsible for the production of melatonin. The vitamin helps increase the production of melatonin during the nighttime hours, as well as release it earlier, making it easier to fall and stay asleep.
Side Effects and Risks of Vitamin B Complex
It's possible because, in higher amounts, vitamin B3 can get in the way of diabetes medicines. Therefore, anyone with high blood pressure should not take too much vitamin B3. High amounts of nicotinic acid can also lead to headaches, fatigue, low blood pressure, and more.
Fat-soluble and water-soluble vitamins
Some combinations should be avoided, even if they aren't inherently problematic. For example, although it's safe to take vitamin D with vitamin B12, it's not advisable, says Virgilio Sanchez, MD, a board certified family medicine physician at Conviva Care Center in Miami, Florida.
Furthermore, caffeine interferes with the metabolism of certain B vitamins, including thiamine. However, because caffeine increases stomach acid secretion, it actually boosts the absorption of vitamin B12.
Take them with or without food, with one exception: You'll absorb B12 better with a meal. If you also use vitamin C, put 2 hours between them. Vitamin C can keep your body from using B12.
Symptoms of Vitamin B12 Deficiency
A mild deficiency may cause no symptoms. But if untreated, it may lead to symptoms such as: Weakness, tiredness, or lightheadedness. Heart palpitations and shortness of breath.
Vitamin B-12 can cause very rare but serious allergic reactions (anaphylaxis). This includes swelling of the face, tongue, and throat, and difficulty swallowing and breathing. If this occurs after you take vitamin B-12, call 911 or your local emergency services immediately.
There is no risk of an overdose when taking large amounts of vitamin B-12 such as 1000 mcg, because it is a water-soluble vitamin. Meaning the body will use the amount that it needs then the excess will be excreted through urine.
Due to its special role, vitamin B12 aids in the prevention of anemia, which mostly leads to fatigue. Even though the research available about the relationship between vitamin B12 and insomnia remains unclear, some studies² show that elevated levels of vitamin B12 do cause sleeplessness.
B12 also plays a role in the production of melatonin, a hormone that helps regulate our circadian rhythms. It is possible that a deficiency of B12 could lead to disrupted sleep patterns. Vitamin B12 also helps in the production of energy.
As summarized in the table provided, vitamin B12 (cobalamin) absorption and utilization by the body can be compromised with the chronic use of certain medications which include: colchicine, chloramphenicol, ethanol, histamine 2 receptor antagonists (H2RA), metformin, and proton pump inhibitors (PPI).
You may think that bright yellow urine is a sign that you should cut down on your B vitamin intake. However, that is not the case! Because these vitamins are water-soluble, you cannot overdose on these vitamins or experience negative symptoms other than a change in urine color.
Though doses of up to 2,000 mcg of vitamin B12 are considered safe, it's best to speak with a doctor to find out whether taking a supplement is necessary. Most people can fulfill their B12 needs through a nutrient-rich diet.
Diet. Some people can develop a vitamin B12 deficiency as a result of not getting enough vitamin B12 from their diet. A diet that includes meat, fish and dairy products usually provides enough vitamin B12, but people who do not regularly eat these foods can become deficient.
If your vitamin B12 deficiency is not caused by a lack of vitamin B12 in your diet, you'll usually need to have an injection of hydroxocobalamin every 2 to 3 months for the rest of your life.
Bananas also contain fibre and potassium. It helps manage blood pressure, reduce stress, and relieve constipation and ulcer problems. The fruit also helps regulate body temperature. Another fruit that is rich in vitamin B12 is blueberries.