High magnesium levels (
At the same time, magnesium interacts with hormones (cortisol, adrenaline) and neurotransmitters (GABA) to minimize anxiety and stress, which can improve sleep quality. Magnesium also seems to regulate the pineal gland's release of melatonin, a hormone essential to making us feel sleepy at the right times.
Early signs of excessive magnesium intake can include low blood pressure, facial flushing, depression, urine retention, and fatigue. Eventually, if untreated, these symptoms can worsen and include muscle weakness, difficulty breathing, irregular heartbeat, and even, in very rare cases, cardiac arrest.
Although it's important to get adequate amounts of magnesium, be aware that taking excessive amounts of magnesium from supplements or over-the-counter laxatives and antacids can cause elevated blood levels of magnesium, which can lead to low blood pressure, drowsiness, muscle weakness, slowed breathing, and even death.
Very low magnesium levels may cause:
Headaches. Nighttime leg cramps. Numbness or tingling in the legs or hands. General body weakness.
Side effects of magnesium
Taking magnesium supplements can bring a range of side effects, such as drowsiness or fatigue during the day, muscle weakness, nausea, vomiting, skin flushing or diarrhea, Gurubhagavatula said. Some risks are even more serious.
When taken in very large amounts (greater than 350 mg daily), magnesium is POSSIBLY UNSAFE. Large doses might cause too much magnesium to build up in the body, causing serious side effects including an irregular heartbeat, low blood pressure, confusion, slowed breathing, coma, and death.
Too much magnesium from food does not pose a health risk in healthy individuals because the kidneys eliminate excess amounts in the urine [29]. However, high doses of magnesium from dietary supplements or medications often result in diarrhea that can be accompanied by nausea and abdominal cramping [1].
Generally speaking, you will find that magnesium supplements start to work after one week of using them. After one week of regular magnesium supplementation, individuals may experience benefits such as improved energy levels, reduced muscle cramps, better sleep quality, and reduced anxiety.
Antibiotics: Taking magnesium supplements may reduce the absorption of quinolone antibiotics, tetracycline antibiotics, and nitrofurantoin (Macrodandin). Magnesium should be taken 1 hour before or 2 hours after taking these medications. Quinolone and tetracycline antibiotics include: Ciprofloxacin (Cipro)
Magnesium is important for maintaining muscle and nervous system function, cardiac electrical properties, and for supporting immune system as well as regulating glucose and insulin metabolism [2,3].
You're taking too much: You can also feel worse on magnesium if you take too much, too soon. This usually happens if you have fatigue and weakness from magnesium deficiency. Anyone in this category should start very slowly on any new supplement or drug.
“Magnesium is essential for brain function and acts on NMDA receptors in the brain which help brain development, learning and memory. It also helps with fatigue, tension, anxiety, mood, sleep and healthy functioning of the entire nervous system”.
The benefits of magnesium supplementation in healthy individuals aren't clear, but Dr. Nassar says that taking a magnesium supplement every day likely isn't unsafe for most people. Just be sure you're not taking too much magnesium. The maximum dietary allowance for most adults is around 400 mg or less.
Never begin taking, suddenly discontinue, or change the dosage of any medication without your doctor's recommendation. Severe interactions with magnesium supplement include: baloxavir marboxil.
Intravenous calcium, diuretics, or water pills may also be used to help the body get rid of excess magnesium. People with renal dysfunction or those who have had a severe magnesium overdose may require dialysis if they are experiencing kidney failure, or if magnesium levels are still rising after treatment.
People with diabetes, intestinal disease, heart disease or kidney disease should not take magnesium before speaking with their health care provider. Overdose. Signs of a magnesium overdose can include nausea, diarrhea, low blood pressure, muscle weakness, and fatigue. At very high doses, magnesium can be fatal.
Side effects from too much magnesium are unusual, because the body clears excess magnesium naturally. In rare cases, magnesium toxicity can cause dizziness or fainting, flushing, or muscle paralysis.
Every organ in the body, especially the heart, muscles, and kidneys, needs the mineral magnesium. It also contributes to the makeup of teeth and bones. Magnesium is needed for many functions in the body. This includes the physical and chemical processes in the body that convert or use energy (metabolism).
Magnesium sulfate usually takes effect immediately and can stay in your system for at least several hours and up to about 24 hours. After treatment with high doses of magnesium, levels usually return to normal within a few days.
This ongoing process of absorption and utilization is pretty quick, so it's important to make sure you're always giving your body the magnesium it needs. “Most magnesium will stay in the body for anywhere from 12 to 24 hours.