Why is it hard to treat metastasis?

It could possibly be due to the basic biology of metastatic tumors and the lack of treatments that target their biology. For example, the genetic characteristics of metastatic tumors may make them highly resistant to standard treatments. Another thing is that each metastatic tumor may be growing in a different organ.

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Why can't you cure metastatic cancer?

Rarely are the terms “cure” and “metastatic cancer” used together. That's because cancer that has spread from where it originated in the body to other organs is responsible for most deaths from the disease.

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What is the problem with metastasis?

This means that the cancer cells can travel far from the original tumor and form new tumors when they settle and grow in a different part of the body. Metastases can also develop when cancer cells from the main tumor break off and grow in nearby areas, such as in the liver, lungs, or bones.

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Can you survive cancer metastasis?

Some people can live for years with metastatic cancer that is well controlled. Other treatments may improve the quality of life by relieving symptoms. This type of care is called palliative care. It can be given at any point during treatment for cancer.

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How long can a person live with metastasis?

A patient with widespread metastasis or with metastasis to the lymph nodes has a life expectancy of less than six weeks. A patient with metastasis to the brain has a more variable life expectancy (one to 16 months) depending on the number and location of lesions and the specifics of treatment.

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Why is it so hard to cure cancer? - Kyuson Yun

24 related questions found

Can someone with metastasis be cured?

In most cases, metastatic cancer is not curable. However, treatment can slow growth and ease many of the associated symptoms. It's possible to live for several years with some types of cancer, even after it has metastasized. Some types of metastatic cancer are potentially curable, including melanoma and colon cancer.

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How do you treat metastasis?

Typically, metastatic cancer requires systemic therapy, or medications given by mouth or injected into the bloodstream to reach cancer cells throughout the body, such as chemotherapy or hormone therapy. Other treatments may include immunotherapy, radiation therapy, surgery, or a combination of these.

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How do you fix metastasis?

Common treatments for bone metastasis include medications, radiation therapy and surgery.
...
Treatment
  1. Bone-building medications. ...
  2. Intravenous radiation. ...
  3. Chemotherapy. ...
  4. Hormone therapy. ...
  5. Pain medications. ...
  6. Steroids. ...
  7. Targeted therapy.

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Do oncologists lie about prognosis?

Many have fulminated against oncologists who lie to patients about their prognoses, but sometimes cancer doctors lie for or with patients to improve our chances of survival. Here's the back story in this case. The patient, a woman in her early 50s, was given a diagnosis of endometrial cancer.

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Why is metastatic cancer so painful?

The pain is from structural damage to the bones and inflammation caused by cancer cells. Sometimes the pain is related to a bone fracture. Bone metastases can't be cured, but treatments can help prevent further spread of cancer and alleviate symptoms like bone pain.

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Can you go into remission with metastatic cancer?

Metastatic breast cancer may never go away completely. But treatment can control its spread. Cancer may even go into remission at some points. This means you have fewer signs and symptoms of cancer.

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Is there hope for metastatic cancer?

In the past, many people did not live long with metastatic cancer. Even with today's better treatments, recovery is not always possible. But doctors can often treat cancer even if they cannot cure it. A good quality of life is possible for months or even years.

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Why do oncologists stop chemo?

What the experts recommend. Cancer treatment is at its most effective the first time that it's used. If you've undergone three or more chemotherapy treatments for your cancer and the tumors continue to grow or spread, it may be time for you to consider stopping chemotherapy.

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Why do oncologists lie to patients?

When asked, most oncologists say that they don't want to take away their patients' hope of recovery. Others say they are afraid that if they tell them the truth, the patients will stop treatment. Some worry that their patients will leave and seek the advice of another physician.

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When Should I fire my oncologist?

The simple answer is that you have the right to change oncologists any time you want. An even more reasonable answer is that you should consider a change if and when you're uncomfortable with an important aspect of your care, and you can't resolve that concern with your current oncologist.

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What organ is the most common site of metastasis?

The lungs. The lungs are the most common organ for cancers to spread to. This is because the blood from most parts of the body flows back to the heart and then to the lungs. Cancer cells that have entered the bloodstream can get stuck in the small blood vessels (capillaries) of the lungs.

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Does metastasis mean death?

Metastasis is the general term used to describe the spread of cancer cells from the primary tumor to surrounding tissues and to distant organs and is the primary cause of cancer morbidity and mortality. It is estimated that metastasis is responsible for about 90% of cancer deaths.

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What triggers metastasis?

Cancer metastasizes due to several factors, namely attack by the immune system, lack of oxygen and necessary nutrients, large amounts of lactic acid produced by glycolysis and increased cell death. Therefore, the majority of the presently available treatments for cancer also bear the potential to induce metastasis.

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What is the survival rate of metastasized?

The five-year survival rate for people diagnosed with late-stage lung cancer that has spread (metastasized) to other areas of the body is 6 percent. Overall survival rates don't specify whether cancer survivors are still undergoing treatment at five years or if they've become cancer-free (achieved remission).

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What are the 4 steps of metastasis?

  • Step 1: invasion and migration. ...
  • Step 2: angiogenesis and intravasation. ...
  • Step 3: survival in the circulation and attachment to the endothelium. ...
  • Step 4 and 5: extravasation and colonization.

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Is metastatic painful?

Bone metastasis can cause pain and broken bones. With rare exceptions, cancer that has spread to the bones can't be cured. Treatments can help reduce pain and other symptoms of bone metastases.

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Which cancers spread the fastest?

Examples of fast-growing cancers include:
  • acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML)
  • certain breast cancers, such as inflammatory breast cancer (IBC) and triple-negative breast cancer (TNBC)
  • large B-cell lymphoma.
  • lung cancer.
  • rare prostate cancers such as small-cell carcinomas or lymphomas.

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When is it time to give up chemo?

Some reasons why you might consider stopping include: Your cancer is advanced, and further treatment won't make a big difference in how long you live. You've tried multiple treatments that haven't worked. The risks or side effects of treatment outweigh the benefits.

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When is chemo not an option?

Because of chemotherapy's possible risks and side effects, it is not always recommended. Your oncologist may recommend avoiding chemotherapy if your body is not healthy enough to withstand chemotherapy or if there is a more effective treatment available.

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How long does palliative chemo prolong life?

For most cancers where palliative chemotherapy is used, this number ranges from 3-12 months. The longer the response, the longer you can expect to live.

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