Muzan may be strong, but Madara is on a whole other level. Madara has Sharingan, Rinnegan, and wood-style jutsu, while Muzan just has some fancy demon powers. He could easily read Muzan's moves with Sharingan, then use wood-style jutsu to pin him down.
Hashirama Senju
This one is a pretty obvious choice, but it's worth restating. The legendary First Hokage, Hashirama Senju was known as the "God of Shinobi" for a reason. He was the only one capable of defeating Madara Uchiha during the latter's early life.
3) Madara Uchiha
At the height of his power, he was able to slaughter entire groups of ninja, take on the Kage, and slice the tops of mountains off! Alone, Boruto wouldn't stand much of a chance.
But as powerful as Muzan is, his skills can't compete with someone like Goku. His regeneration abilities won't stand up to a full-power Kamehameha, and that's without getting to Goku being far stronger and faster than Muzan can hope to be.
Muzan Kibutsuji was born during the Heian Era of ancient Japan to a noble family. Ever since he was in his mother's womb, Muzan was extremely frail and weak.
Yoriichi combined all his forms into one strike and turned his blade bright red, enabling him to cut through all of Muzan's weaknesses and overpower him.
4) Madara Uchiha
Being an eternal rival of Hashirama Senju and defeating him during the war arc went on to show just how powerful he could become with Rinnegan. Hinata will have no chance of defeating the strongest Uchiha ever to live.
Sasuke was stated to be the strongest Uchiha to ever have been born, including Madara. So, obviously, his powers do exceed Madara's. With his Choku-tomou Rinnegan and Indra's arrow, he is almost invincible. As a result, he is also one of the Naruto characters who can defeat Madara.
Black Zetsu was central to one of the biggest shocks in Naruto during the 4th Great Ninja War. It was he who stabbed Madara Uchiha in the back and struck him down when he was at the pinnacle of his powers. Zetsu was then revealed to be the perpetrator of the plan to bring Kaguya back.
The warrior Muzan feared was a swordsman named Yoriichi Tsugikuni. Yoriichi was the only slayer before Tanjiro who came close to killing Muzan, and the flashback of their fight occurred in Chapter 187.
Kokushibo is one of the strongest demons in the anime, only second to Demon King Muzan. Before turning into a demon, he was a part of the Demon Slayer Corps alongside his brother Yoriichi Tsugikini.
Muzan can detect the locations of his demons and can also read their thoughts. However, Nezuko and Tamayo are the only exceptions in the entirety of Demon Slayer, over whom Muzan has no control.
Considering that Madara was able to summon two gigantic meteors lethal enough to wipe out the Allied Shinobi Forces, he'd be able to destroy Eren's entire head before the wall titans could assist him.
Muzan may be strong, but Madara is on a whole other level. Madara has Sharingan, Rinnegan, and wood-style jutsu, while Muzan just has some fancy demon powers.
The biggest rival of Madara Uchiha, Hashirama was the First Hokage of Konohagakure. Having grown up together, the two shared quite a great bond with each other, however, it worsened over time. They fought several times throughout their lifetime and Hashirama is known to have won most of them.
Sadly enough, Zoro would have trouble fighting Naruto's most powerful Uchiha due to the Sharingan. Madara would avoid Zoro's attacks without even breaking a sweat, ending the fight only with a few hits.
This is simply because of the fact that Madara possesses one thing that Pain would never stand a chance against, and it's not his nearly unparalleled taijutsu abilties, powerful visual genjutsu, extremely powerful ninjutsu, or keen battlefield intellect, though all the factors would make it even easier for Madara.
7 Weakness: Madara Is Vulnerable To Taijutsu
After mastering the Ten-Tails, Madara became incredibly resilient to all forms of ninjutsu and genjutsu, with the exception of Sage Mode. However, he was still vulnerable to the physical force of taijutsu, providing a weakness that Might Guy was more than happy to exploit.
1 CAN'T BEAT: Madara Uchiha
To defeat such a character, one would have to possess the powers of a God itself. Unfortunately for Sakura, she doesn't have any such power. Her strength pales in comparison to Madara's, and so does everything else about her.
Madara Uchiha is among the most powerful shinobi to have ever lived, and his power only increased when he attained the power of the Sage of the Six Paths. He was able to fend off both Naruto Uzumaki and Sasuke Uchiha for a time in this form, and Kakashi Hatake would likely be unable to subdue Madara on his own.
Itachi would have surpassed Madara Uchiha if things were different for him. He learned every powerful Jutsu at a very young age and had a whole life to hone his skills and strength. However, he died too soon and his true potential never saw the light of day.
Yoriichi Tsugikuni was the first Demon Slayer and also the one who invented Breathing Techniques in the first place. Yoriichi was born with the Demon Slayer mark and prowess in swordsmanship. His powers were beyond comparison as he defeated Muzan once and had him on the verge of death until he managed to escape.
In conclusion, Tanjiro will not be able to kill Muzan by himself since the Demon King is far superior in every aspect of combat. The manga has shown fans the singular way that Muzan could be bested and it was only due to the collective efforts of Demon Slayer Corps members.
In the first few arcs of the series, the identity of the demon that killed Tanjiro's family was a mystery. It is later revealed that it was none other than the series' main antagonist, Muzan Kibutsuji.