Can I take magnesium with other minerals and vitamins? Yes. Vitamins and minerals all work in combination and rely on each other to be fully effective. Taking magnesium supplements helps your body to absorb and use types of minerals such as calcium, phosphorus and potassium, and vitamins like vitamin D.
Don't use calcium, zinc, or magnesium supplements at the same time. Also, these three minerals are easier on your tummy when you take them with food, so if your doctor recommends them, have them at different meals or snacks.
No interactions were found between magnesium sulfate and Vitamin B12.
Can you take vitamin D and magnesium together? Yes. In fact, it's probably best to take both together. Because so many people have low magnesium levels, vitamin D supplements on their own aren't very helpful for a large portion of the population.
Vitamin C (ascorbic acid) supplements.
Taking vitamin B-12 with vitamin C might reduce the available amount of vitamin B-12 in your body. To avoid this interaction, take vitamin C two or more hours after taking a vitamin B-12 supplement.
Vitamins D, E and K
“Studies have shown that a person's absorption of Vitamin K may be reduced when other fat-soluble vitamins such as Vitamin E and Vitamin D are taken together,” says Dr. Chris Airey, M.D. “It's advised that you take these vitamins at least 2 hours apart to maximize your absorption.”
"Adequate levels of magnesium in the body are essential for the absorption and metabolism not only of vitamin D but of calcium as well," Dean states. "Magnesium converts vitamin D into its active form so that it can help calcium absorption.
So, get enough vitamin D—just take it in the morning or afternoon. At night, take supplements that support sleep quality and muscle relaxation, like magnesium and melatonin (which you'll find in soothing, sippable Bulletproof Sleep Collagen Protein).
It is a good idea to take magnesium before bed because it can help you sleep. Because calcium and magnesium compete for absorption, they should not be consumed at the same time. Another reason that it is not good to take calcium at night is because vitamin D should be combined with complete meals.
You should take water-soluble vitamins and minerals on an empty stomach as your body will more easily absorb and metabolize them, says Alana Kessler, a registered dietitian and nutrition consultant based in New York City.
A 2019 study also found that taking a supplement of magnesium, melatonin, and vitamin B complex for 3 months improved sleep and helped treat insomnia.
Fat-soluble and water-soluble vitamins
For example, although it's safe to take vitamin D with vitamin B12, it's not advisable, says Virgilio Sanchez, MD, a board certified family medicine physician at Conviva Care Center in Miami, Florida.
When taken together, magnesium and zinc have mutual benefits. Magnesium helps your body regulate its zinc levels, while zinc does the job of allowing it to absorb magnesium more effectively. Taking magnesium alongside zinc is good for supporting your body to: process food and food supplements.
Medications that slow blood clotting (Anticoagulant / Antiplatelet drugs) interacts with MAGNESIUM. Magnesium might slow blood clotting. Taking magnesium along with medications that also slow clotting might increase the chances of bruising and bleeding.
If you are supplementing with vitamin D3, it's imperative you have enough magnesium to activate it. Why is this so important? Vitamin D3 cannot be utilized without sufficient magnesium; it simply remains stored in the body until it has enough magnesium to be activated.
Phytates in the diet bind to magnesium and impair its absorption. However the quantities present in normal diet do not affect magnesium absorption. Other dietary factors that are thought to affect magnesium absorption are oxalate, phosphate, proteins, potassium and zinc.
Consumption of vitamin D supplements without enough magnesium can lead to problems such as vascular calcification. Calcification happens when calcium builds up in body tissue, blood vessels, or organs and vascular calcification refers to build-up in the arteries and veins.
“Take water-soluble vitamins on an empty stomach with a glass of water,” recommends Dr. Perez-Gallardo. And since it can be energizing, Dr. Perez-Gallardo says that the best time to take vitamin B12 is in the morning, so it won't affect your sleep.
Magnesium deficiency is diagnosed via a blood test and sometimes a urine test. Your doctor may order the blood test if you have symptoms such as weakness, irritability, abnormal heart rhythm, nausea and/or diarrhoea, or if you have abnormal calcium or potassium levels.
You can definitely opt for taking vitamin B12 supplements at night if that's what works best for you, although the natural energy-boosting abilities of vitamin B12 might be put to better use as you're starting the day.
Even though the research available about the relationship between vitamin B12 and insomnia remains unclear, some studies² show that elevated levels of vitamin B12 do cause sleeplessness.
Nassar says that taking a magnesium supplement every day likely isn't unsafe for most people. Just be sure you're not taking too much magnesium. The maximum dietary allowance for most adults is around 400 mg or less.
The Perfect Pair: KAL Magnesium Glycinate helps activate the action of Vitamin D, the “sunshine vitamin,” to support calcium absorption, strong bones muscle and immune health and more.
“Vitamin D is fat-soluble, meaning it needs fat to be absorbed,” says Conner. For that reason, she always recommends pairing vitamin D-rich foods with a high-quality fat, like olive oil, flax seeds, avocado, fish, chia seeds, or nuts. Just a couple teaspoons of oil or a handful of nuts will do the trick, she says.