Some individuals may actually gain more weight after stopping an obesity drug than they initially lost, Conde-Knape added. Studies have similarly shown weight rebound in people who stop taking Ozempic.
Describing her experience maintaining her weight loss after stopping semaglutide, Shepherd said, "Absolutely people can get off of it and do it, and I wouldn't be scared to get off of it." Teresa Shepherd, of Florida, said she lost 90 pounds while taking a semaglutide compound for around eight months.
As soon as someone stops taking the drug, their body fat and former appetite tend to return. Experts recommend working with a provider versed in obesity medicine to create a plan for improved lifestyle and long-term adherence to the drug.
Once you begin using Ozempic, some people can find it takes several weeks to see any weight loss, yet others may see some weight loss within a week or 2. While it can be difficult, try to remain patient — change looks different for everyone.
You start feeling those usual hunger pangs again, and consequently, you may start eating more to satisfy that hunger. An increase in your consumption can lead to the regaining of weight that was lost. A 2022 study found that most individuals gain weight back a year after stopping the medication.
Another study, published in August 2022, found that one year after participants stopped taking semaglutide, they regained two-thirds of the weight they had lost. Weight gain can start to happen pretty immediately after you stop injecting Ozempic, or the other similar medications.
Similarly Gabel advises that if you're thinking about stopping Ozempic (and don't have a reason like pregnancy to stop cold turkey), try to taper off slowly to let the body adjust.
Why You Regain Weight After Stopping Semaglutide. The reason you're likely to regain weight after using semaglutide medication is that the drug is not a cure for metabolic factors that cause regain after weight loss.
Activity that uses 1,500 to 2,000 calories per week is recommended for maintaining weight loss. Adults should try to get at least 40 minutes of moderate to vigorous level physical activity at least 3 to 4 times per week. Diet and exercise are vital strategies for losing and maintaining weight.
The FDA recommends that the dosage of semaglutide medication must be increased to its effective level of 2.4 mg during the 16 to 20 weeks of the therapy to include its weight loss benefits and other advantages and to reduce the impact of common side effects like gastrointestinal disorders.
If you take Wegovy or Ozempic to lose weight, will you need to keep taking the drugs indefinitely? Yes. As with many chronic conditions, most people who use the drugs for diabetes or weight loss will need to keep taking them to keep benefiting from them.
“Ozempic face” is a term for common side effects of the type 2 diabetes medication semaglutide (Ozempic). It can cause sagging and aging of facial skin. A doctor may recommend lifestyle modifications or facial fillers to treat these effects.
Semaglutide (Ozempic, Wegovy, Rybelsus) can cause side effects that some people are unable to tolerate. Following dosing guidelines can help manage these side effects. Nausea, vomiting, and diarrhea are the most common semaglutide side effects.
Semaglutide improves postprandial glucose and lipid metabolism, and delays first-hour gastric emptying in subjects with obesity. Diabetes Obes Metab.
However, other studies show that while consuming 1,000 calories a day may result in significant weight loss, most people cannot sustain it and often experience significant weight regain . The reasons include regaining lost muscle mass and increased appetite. Also worth noting is that the human body can adapt.
If you eat too much and exercise too little, you're likely to carry excess weight — including belly fat. Also, your muscle mass might diminish slightly with age, while fat increases.
If you don't have diabetes, taking Ozempic for weight loss is considered an off-label use. Wegovy, a higher-dose version of Ozempic, is approved to help people manage their weight. This includes adults and adolescents ages 12 and older who meet certain body mass index (BMI) criteria.
So, on average, with the recommended starting Ozempic dose of 0.25 mg, a 500 to 1000 calorie reduced diet, and exercise 3 times a week, you can expect to lose 3-5 pounds in the first month of treatment, which works out to about 3% of body weight for most overweight or obese individuals.
Our brains are hardwired to avoid starvation, so when we consume less food and lose weight, our brains and bodies instinctively react to stop us from losing weight and to restore the weight we have lost. The brain is always trying to achieve homeostasis – a balanced state of normalcy.
The Bottom Line
As we've mentioned, eating less than 1000 calories a day will lead to a slowed metabolism, loss of muscle mass, malnutrition, the body to enter into starvation mode and all of this is not healthy for you. There are healthy approaches you can implement to lose weight.