Anxiety symptoms The repeated-measures ANOVA showed a significant effect of time (P<0.00001), indicating that both high-dose and low-dose betahistine could significantly reduce the HARS score.
Betahistine therapy was also accompanied by progressive improvements in mean Hospital Anxiety and Depression anxiety and depression scores (P<0.0001) and significant improvements in both the physical and mental component summary of the SF-36v2 (P<0.0001).
Antihistamines, e.g. betahistine and cinnarizine. These are sedative, and patients should not operate machinery or drink alcohol.
Betahistine is a medicine used to treat the symptoms of Ménière's disease. These symptoms include: feeling dizzy and a spinning sensation (vertigo) ringing in the ears (tinnitus)
Betahistine enters the CNS and improves histaminergic neurotransmission (12). Although several studies have reported subsequent improvements in cognitive function (12–16), they have shown conflicting findings on the effects of betahistine on cognition.
Corresponding improvements occurred in all three DHI scale domains (all p < 0.001 vs baseline). Betahistine therapy was also accompanied by progressive, significant improvements in both HADS-A and HADS-D scores (p < 0.001), and improvements in the distribution profiles of anxiety and depression scores.
More importantly, the powerful antagonistic effects of betahistine at H3 receptors could increase the levels of serotonin, acetylcholine, neurotransmitter histamine, and norepinephrine released from the nerve endings.
It usually takes 1 to 2 weeks before any response to betahistine is noticeable. If you forget to take your dose, take it as soon as you remember that day. But, if it is nearly time for your next dose, just take the next dose at the right time.
Taking too much betahistine can make you feel sick or sleepy, or give you stomach ache.
Your doctor may advise a trial of betahistine for 6-12 months to see if it helps to reduce your symptoms. If it does, it can then be continued. Some people with Ménière's disease claim their symptoms improve with a low-salt diet, regular exercise, stopping smoking, and cutting out caffeine and alcohol.
Do not stop taking this medicine suddenly, or change the dosage, without checking with your doctor. Do not use this medicine to treat any other complaints unless your doctor or pharmacist tells you to. Do not give this medicine to anyone else, even if they have the same condition as you.
Betahistine in a dose of 16 mg three times daily is an effective antivertigo therapy, which improves blood perfusion to ischaemic areas of the brain.
The dizziness that accompanies anxiety is often described as a sense of lightheadedness or wooziness. There may be a feeling of motion or spinning inside rather than in the environment. Sometimes there is a sense of swaying even though you are standing still.
Yes, vertigo causes extreme anxiety in most people. Anxiety, by itself, does not produce vertigo. However, in association with conditions that do produce vertigo, anxiety can make the vertigo much worse. People with certain anxiety disorders such as panic attacks can sometimes also experience vertigo.
Staying active, finding ways to control your breathing, talking out your anxieties, and coming up with ways to de-escalate stressful situations can all provide relief from dizziness caused by anxiety.
Whilst histamine has positive inotropic effects on the heart, betahistine is not known to increase cardiac output and its vasodilator effect may produce a small fall in blood pressure in some patients.
A person on betahistine should be able to take purely "peripheral" acting antihistamines (such as Claratin, Allegra and Zyrtec). Similarly a person on betahistine should not take antidepressants with central antihistamine side effects such as the "tryptylines". This includes Elavil and Pamelor.
It is often promoted as a vestibular stimulant, but scientific evidence suggests that it is a vestibular suppressant.
Betahistine is an antivertigo agent used for the reduction of episodes of vertigo association with Ménière's disease. Ménière's disease is a progressive disease of the inner ear characterized by vertigo, tinnitus, and hearing loss.
Some medicines and betahistine affect each other and can increase your chance of side effects. Tell your pharmacist or doctor if you're taking: medicines called MAO inhibitors, used to treat depression or Parkinson's disease. antihistamines for allergies such as hay fever.
Keep taking your tablets until your doctor tells you to stop. Even when you start feeling better, your doctor may want you to carry on taking the tablets for some time to make sure that the medicine has worked completely.
Therefore, an increase in histamine release or enhancement of histaminergic signal by betahistine by directly stimulating histamine receptors may inhibit the consumption of tasty foods and thus the development of obesity.
Weight-reducing potential of betahistine has been linked to its action on the hypothalamus and liver to induce thermogenesis and reduce food intake. An RCT in 48 healthy females who received cotreatment with olanzapine and betahistine reported a 37% reduction in the mean weight gain in the betahistine group.